Efficient multiplexed integration of synergistic alleles and metabolic pathways in yeasts via CRISPR-Cas AA Horwitz, JM Walter, MG Schubert, SH Kung, K Hawkins, DM Platt, ... Cell systems 1 (1), 88-96, 2015 | 357 | 2015 |
Rewiring cells: synthetic biology as a tool to interrogate the organizational principles of living systems CJ Bashor, AA Horwitz, SG Peisajovich, WA Lim Annual review of biophysics 39 (1), 515-537, 2010 | 228 | 2010 |
BRCA1/BARD1 Ubiquitinate Phosphorylated RNA Polymerase II LM Starita, AA Horwitz, MC Keogh, C Ishioka, JD Parvin, N Chiba Journal of Biological Chemistry 280 (26), 24498-24505, 2005 | 187 | 2005 |
ABCA1 mediates concurrent cholesterol and phospholipid efflux to apolipoprotein AI JD Smith, W Le Goff, M Settle, G Brubaker, C Waelde, A Horwitz, MN Oda Journal of lipid research 45 (4), 635-644, 2004 | 186 | 2004 |
Evaluation of the role of phosphatidylserine translocase activity in ABCA1-mediated lipid efflux JD Smith, C Waelde, A Horwitz, P Zheng Journal of Biological Chemistry 277 (20), 17797-17803, 2002 | 152 | 2002 |
Methods for genomic modification Z Serber, A Horwitz US Patent 8,685,737, 2014 | 99 | 2014 |
BRCA1 DNA-binding activity is stimulated by BARD1 AM Simons, AA Horwitz, LM Starita, K Griffin, RS Williams, JNM Glover, ... Cancer research 66 (4), 2012-2018, 2006 | 85 | 2006 |
Direct DNA binding activity of the Fanconi anemia D2 protein WH Park, S Margossian, AA Horwitz, AM Simons, AD D'Andrea, JD Parvin Journal of Biological Chemistry 280 (25), 23593-23598, 2005 | 84 | 2005 |
Identification of cAMP analogue inducible genes in RAW264 macrophages Y Takahashi, M Miyata, P Zheng, T Imazato, A Horwitz, JD Smith Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1492 (2-3 …, 2000 | 82 | 2000 |
Multiple mechanisms contribute to inhibit transcription in response to DNA damage GF Heine, AA Horwitz, JD Parvin Journal of Biological Chemistry 283 (15), 9555-9561, 2008 | 65 | 2008 |
ATP-induced structural transitions in PAN, the proteasome-regulatory ATPase complex in Archaea AA Horwitz, A Navon, M Groll, DM Smith, C Reis, AL Goldberg Journal of Biological Chemistry 282 (31), 22921-22929, 2007 | 58 | 2007 |
A mechanism for transcriptional repression dependent on the BRCA1 E3 ubiquitin ligase AA Horwitz, EB Affar, GF Heine, Y Shi, JD Parvin Proceedings of the National Academy of Sciences 104 (16), 6614-6619, 2007 | 54 | 2007 |
Genetic sensor for strong methylating compounds F Moser, A Horwitz, J Chen, WA Lim, CA Voigt ACS synthetic biology 2 (10), 614-624, 2013 | 45 | 2013 |
Challenging the workhorse: Comparative analysis of eukaryotic micro‐organisms for expressing monoclonal antibodies H Jiang, AA Horwitz, C Wright, A Tai, EA Znameroski, Y Tsegaye, ... Biotechnology and Bioengineering 116 (6), 1449-1462, 2019 | 34 | 2019 |
BRCA1 represses amphiregulin gene expression EP Lamber, AA Horwitz, JD Parvin Cancer research 70 (3), 996-1005, 2010 | 31 | 2010 |
CRISPR‐Cas‐Assisted Multiplexing (CAM): Simple Same‐Day Multi‐Locus Engineering in Yeast JM Walter, SS Chandran, AA Horwitz Journal of Cellular Physiology 231 (12), 2563-2569, 2016 | 29 | 2016 |
Stably transfected ABCA1 antisense cell line has decreased ABCA1 mRNA and cAMP-induced cholesterol efflux to apolipoprotein AI and HDL P Zheng, A Horwitz, CA Waelde, JD Smith Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2001 | 28 | 2001 |
Methods for genomic integration A Horwitz, KM Hawkins, M Schubert, W Szeto US Patent 9,476,065, 2016 | 25 | 2016 |
Efficient multiplexed integration of synergistic alleles and metabolic pathways in yeasts via CRISPR-Cas. Cell Syst 1: 88–96 AA Horwitz, JM Walter, MG Schubert, SH Kung, K Hawkins, DM Platt, ... | 24 | 2015 |
Methods for genomic modification Z Serber, A Horwitz US Patent 9,701,971, 2017 | 20 | 2017 |