| Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer’s disease C Cruchaga, D Western, J Timsina, L Wang, C Wang, C Yang, M Ali, ... Research square, 2023 | 23 | 2023 |
| Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease M Ali, DB Archer, P Gorijala, D Western, J Timsina, MV Fernández, ... Acta neuropathologica communications 11 (1), 68, 2023 | 18 | 2023 |
| Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease J Rutledge, B Lehallier, P Zarifkar, PM Losada, M Shahid-Besanti, ... Acta Neuropathologica 147 (1), 52, 2024 | 11 | 2024 |
| Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease L Wang, NP Nykänen, D Western, P Gorijala, J Timsina, F Li, Z Wang, ... Molecular neurodegeneration 19 (1), 1, 2024 | 9 | 2024 |
| Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson’s disease B Phillips, D Western, L Wang, J Timsina, Y Sun, P Gorijala, C Yang, A Do, ... npj Parkinson's Disease 9 (1), 107, 2023 | 9 | 2023 |
| Genetic architecture of plasma Alzheimer disease biomarkers J Bradley, P Gorijala, SE Schindler, YJ Sung, B Ances, MV Fernandez, ... Human molecular genetics 32 (15), 2532-2543, 2023 | 6 | 2023 |
| Unique genetic architecture of CSF and brain metabolites pinpoints the novel targets for the traits of human wellness C Wang, D Western, C Yang, M Ali, L Wang, P Gorijala, J Timsina, A Ruiz, ... Research Square, 2023 | 6 | 2023 |
| Multivariate GWAS of Alzheimer’s disease CSF biomarker profiles implies GRIN2D in synaptic functioning A Neumann, O Ohlei, F Küçükali, IJ Bos, J Timsina, S Vos, D Prokopenko, ... Genome medicine 15 (1), 79, 2023 | 5 | 2023 |
| Integrative analysis of eQTL and GWAS summary statistics reveals transcriptomic alteration in Alzheimer brains P Varathan, P Gorijala, T Jacobson, D Chasioti, K Nho, SL Risacher, ... BMC medical genomics 15 (Suppl 2), 93, 2022 | 3 | 2022 |
| Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome P Gorijala, MM Aslam, LHT Dang, L Xicota, MV Fernandez, YJ Sung, ... Alzheimer's & Dementia 20 (2), 1038-1049, 2024 | 2 | 2024 |
| GWAS for CSF TREM2 levels identify new variants implicated on TREM2 biology and Alzheimer disease S Mafimoghaddam, L Wang, P Gorijala, J Timsina, N Nykanen, F Wang, ... Alzheimer's & Dementia 18, e062517, 2022 | 2 | 2022 |
| Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracell signaling pathways C Cruchaga, J Bradley, D Western, C Wang, ELD Fonseca, A Neupane, ... Research square, rs. 3. rs-4480585, 2024 | 1 | 2024 |
| TOPMed imputed genomics enhances genomic atlas of the human proteome in brain, cerebrospinal fluid, and plasma H Yi, Q Yang, C Repaci, CM Lee, G Heo, J Timsina, P Gorijala, C Yang, ... Scientific data 11 (1), 387, 2024 | 1 | 2024 |
| Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways Y Shen, M Ali, M Liu, J Timsina, C Wang, A Do, D Western, P Gorijala, ... medRxiv, 2024.01. 12.24301242, 2024 | 1 | 2024 |
| Proteome Wide Association Studies of LRRK2 variants identify novel causal and druggable for Parkinson’s disease B Phillips, D Western, L Wang, J Timsina, Y Sun, P Gorijala, C Yang, A Do, ... medRxiv, 2023.01. 05.23284241, 2023 | 1 | 2023 |
| Gene co-expression changes underlying the functional connectomic alterations in Alzheimer’s disease B He, P Gorijala, L Xie, S Cao, J Yan BMC Medical Genomics 15 (Suppl 2), 92, 2022 | 1 | 2022 |
| Functional biological paths altered in Alzheimer’s disease: from genes to bile acids P Gorijala, K Nho, SL Risacher, R Kaddurah-Daouk, AJ Saykin, J Yan Biorxiv, 2020.01. 31.929554, 2020 | 1 | 2020 |
| CSF proteomics identifies early changes in autosomal dominant Alzheimer’s disease Y Shen, J Timsina, G Heo, A Beric, M Ali, C Wang, C Yang, Y Wang, ... Cell, 2024 | | 2024 |
| Genomic surveillance as a scalable framework for precision phage therapy against antibiotic-resistant pathogens M Koncz, T Stirling, HH Mehdi, O Méhi, B Eszenyi, A Asbóth, G Apjok, ... Cell, 2024 | | 2024 |
| Sex-specific genetic regulation of proteomics in cerebrospinal fluid uncovers genetic causes for sex differences in neurodegeneration YJ Sung, L Wang, D Western, J Timsina, P Gorijala, A Ruiz, P Pastor, ... Alzheimer's Association International Conference, 2024 | | 2024 |
Carlos CruchagaProfessor. NeuroGenomics and Informatics Center Director在 wustl.edu 的电子邮件经过验证
