关注
Ka Tat Siu
Ka Tat Siu
Beam Therapeutics
在 beamtx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
An integrated view of cyclin E function and regulation
KT Siu, MR Rosner, AC Minella
Cell cycle 11 (1), 57-64, 2012
1972012
Targeting cyclin-dependent kinases and cell cycle progression in human cancers
L Santo, KT Siu, N Raje
Seminars in oncology 42 (6), 788-800, 2015
1622015
Preclinical activity of CPI-0610, a novel small-molecule bromodomain and extra-terminal protein inhibitor in the therapy of multiple myeloma
KT Siu, J Ramachandran, AJ Yee, H Eda, L Santo, C Panaroni, JA Mertz, ...
Leukemia 31 (8), 1760-1769, 2017
752017
Multiple myeloma cells induce lipolysis in adipocytes and uptake fatty acids through fatty acid transporter proteins
C Panaroni, K Fulzele, T Mori, KT Siu, C Onyewadume, A Maebius, ...
Blood, 2021
542021
Fbw7-dependent cyclin E regulation ensures terminal maturation of bone marrow erythroid cells by restraining oxidative metabolism
Y Xu, KL Swartz, KT Siu, M Bhattacharyya, AC Minella
Oncogene 33 (24), 3161-3171, 2014
342014
Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation
KT Siu, Y Xu, KL Swartz, M Bhattacharyya, S Gurbuxani, Y Hua, ...
Molecular and cellular biology 34 (17), 3244-3258, 2014
312014
Pim2 is important for regulating DNA damage response in multiple myeloma cells
J Ramachandran, L Santo, KT Siu, C Panaroni, N Raje
Blood cancer journal 6 (8), e462-e462, 2016
292016
BCL2 blockade overcomes MCL1 resistance in multiple myeloma
KT Siu, C Huang, C Panaroni, K Mukaihara, K Fulzele, R Soucy, ...
Leukemia 33 (8), 2098-2102, 2019
282019
Effect of the BET inhibitor, Cpi-0610, alone and in combination with lenalidomide in multiple myeloma
KT Siu, H Eda, L Santo, J Ramachandran, M Koulnis, J Mertz, RJ Sims, ...
Blood 126 (23), 4255, 2015
212015
Arachidonic acid induces ferroptosis-mediated cell-death in multiple myeloma
C Panaroni, K Fulzele, R Soucy, KT Siu, K Mukaihara, C Huang, ...
Blood 132, 4498, 2018
82018
Low NCOR2 levels in multiple myeloma patients drive multidrug resistance via MYC upregulation
T Mori, R Verma, R Nakamoto-Matsubara, KT Siu, C Panaroni, KS Fulzele, ...
Blood Cancer Journal 11 (12), 194, 2021
72021
Mature osteoblasts provide a protective niche against multiple myeloma growth and survival within the tumor microenvironment
K Fulzele, C Panaroni, R Soucy, KT Siu, K Mukaihara, N Raje
Blood 132, 4476, 2018
32018
Osteoclast-Induced Immunosuppression Occurs through Dysregulation of Immune Checkpoint Axes in Multiple Myeloma
K Mukaihara, M D'Agostino, C Panaroni, K Fulzele, T Mori, KT Siu, ...
Blood 134, 4382, 2019
22019
The pleiotropic immunosuppressive role of osteoclasts in multiple myeloma
K Mukaihara, KT Siu, C Panaroni, K Fulzele, R Soucy, C Huang, ...
Blood 132, 4447, 2018
22018
Concomitant suppression of IKZF1, IRF4 and Myc contribute to the anti-tumor activity of the BET inhibitor, Cpi-0610, in disease models of multiple myeloma
KT Siu, J Ramachandran, AJ Yee, H Eda, L Santo, EK O'Donnell, ...
Blood 128 (22), 3320, 2016
12016
Effect of the Wnt-Signaling Inhibitor Sclerostin and Bone Marrow Adipocytes on Multiple Myeloma
C Panaroni, KT Siu, KS Fulzele, J Ramachandran, N Raje
Blood 128 (22), 2077, 2016
12016
Developing a systems-based understanding of hematopoietic stem cell cycle control
KT Siu, AC Minella
A Systems Biology Approach to Blood, 189-200, 2014
12014
Overcoming MCL1 Resistance in Multiple Myeloma
KT Siu, C Huang, C Panaroni, K Mukaihara, K Fulzele, R Soucy, J Cidado, ...
Blood 132, 472, 2018
2018
Role of Sclerostin in Multiple Myeloma Progression
C Panaroni, K Fulzele, KT Siu, P Wang, N Raje
Blood 130, 4341, 2017
2017
The Biologic Relevance of PIM Kinases in the Context of Multiple Myeloma and Their Potential As Therapeutic Targets in Combination Drug Therapy
J Ramachandran, L Santo, H Eda, D Chauhan, KT Siu, M Koulnis, ...
Blood 126 (23), 2992, 2015
2015
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