| Antitumor activity and mechanism of action of the cyclopenta [b] benzofuran, silvestrol R Cencic, M Carrier, G Galicia-Vázquez, ME Bordeleau, R Sukarieh, ... PloS one 4 (4), e5223, 2009 | 364 | 2009 |
| Structural conservation of druggable hot spots in protein–protein interfaces D Kozakov, DR Hall, GY Chuang, R Cencic, R Brenke, LE Grove, ... Proceedings of the National Academy of Sciences 108 (33), 13528-13533, 2011 | 276 | 2011 |
| c-Myc and eIF4F are components of a feedforward loop that links transcription and translation CJ Lin, R Cencic, JR Mills, F Robert, J Pelletier Cancer research 68 (13), 5326-5334, 2008 | 216 | 2008 |
| Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F R Cencic, DR Hall, F Robert, Y Du, J Min, L Li, M Qui, I Lewis, S Kurtkaya, ... Proceedings of the National Academy of Sciences 108 (3), 1046-1051, 2011 | 211 | 2011 |
| RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation ME Bordeleau, R Cencic, L Lindqvist, M Oberer, P Northcote, G Wagner, ... Chemistry & biology 13 (12), 1287-1295, 2006 | 201 | 2006 |
| Repurposing CRISPR/Cas9 for in situ functional assays A Malina, JR Mills, R Cencic, Y Yan, J Fraser, LM Schippers, M Paquet, ... Genes & development 27 (23), 2602-2614, 2013 | 168 | 2013 |
| Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage R Cencic, H Miura, A Malina, F Robert, S Ethier, TM Schmeing, J Dostie, ... PloS one 9 (10), e109213, 2014 | 157 | 2014 |
| Selective pharmacological targeting of a DEAD box RNA helicase L Lindqvist, M Oberer, M Reibarkh, R Cencic, ME Bordeleau, E Vogt, ... PloS one 3 (2), e1583, 2008 | 150 | 2008 |
| A cellular response linking eIF4AI activity to eIF4AII transcription G Galicia-Vázquez, R Cencic, F Robert, AQ Agenor, J Pelletier Rna 18 (7), 1373-1384, 2012 | 140 | 2012 |
| Enantioselective Synthesis of the Complex Rocaglate (−)‐Silvestrol B Gerard, R Cencic, J Pelletier, JA Porco Jr Angewandte Chemie 119 (41), 7977-7980, 2007 | 139 | 2007 |
| Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication R Cencic, M Desforges, DR Hall, D Kozakov, Y Du, J Min, R Dingledine, ... Journal of virology 85 (13), 6381-6389, 2011 | 128 | 2011 |
| Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations YM Abbas, BT Laudenbach, S Martínez-Montero, R Cencic, M Habjan, ... Proceedings of the National Academy of Sciences 114 (11), E2106-E2115, 2017 | 116 | 2017 |
| CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary Y Xue, B Meehan, E Macdonald, S Venneti, XQD Wang, L Witkowski, ... Nature communications 10 (1), 558, 2019 | 113 | 2019 |
| CRISPR-mediated drug-target validation reveals selective pharmacological inhibition of the RNA helicase, eIF4A J Chu, G Galicia-Vázquez, R Cencic, JR Mills, A Katigbak, JA Porco, ... Cell reports 15 (11), 2340-2347, 2016 | 112 | 2016 |
| Synthesis of rocaglamide hydroxamates and related compounds as eukaryotic translation inhibitors: synthetic and biological studies CM Rodrigo, R Cencic, SP Roche, J Pelletier, JA Porco Jr Journal of medicinal chemistry 55 (1), 558-562, 2012 | 112 | 2012 |
| Biomimetic photocycloaddition of 3-hydroxyflavones: synthesis and evaluation of rocaglate derivatives as inhibitors of eukaryotic translation SP Roche, R Cencic, J Pelletier, JA Porco Jr Angewandte Chemie (International ed. in English) 49 (37), 6533, 2010 | 82 | 2010 |
| Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells R Cencic, M Carrier, A Trnkus, JA Porco Jr, M Minden, J Pelletier Leukemia research 34 (4), 535-541, 2010 | 82 | 2010 |
| Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A R Cencic, F Robert, G Galicia-Vazquez, A Malina, K Ravindar, R Somaiah, ... Blood cancer journal 3 (7), e128-e128, 2013 | 80 | 2013 |
| Hippuristanol-A potent steroid inhibitor of eukaryotic initiation factor 4A R Cencic, J Pelletier Translation 4 (1), e1137381, 2016 | 77 | 2016 |
| Targeting translation dependence in cancer A Malina, R Cencic, J Pelletier Oncotarget 2 (1-2), 76, 2011 | 76 | 2011 |
