| Overexpression of both CXC chemokine receptor 4 and vascular endothelial growth factor proteins predicts early distant relapse in stage II-III colorectal cancer patients A Ottaiano, R Franco, A Aiello Talamanca, G Liguori, F Tatangelo, ... Clinical cancer research 12 (9), 2795-2803, 2006 | 251 | 2006 |
| The controversial role of ABC transporters in clinical oncology A Tamaki, C Ierano, G Szakacs, RW Robey, SE Bates Essays in biochemistry 50, 209-232, 2011 | 247 | 2011 |
| Human melanoma metastases express functional CXCR4 S Scala, P Giuliano, PA Ascierto, C Ieranò, R Franco, M Napolitano, ... Clinical cancer research 12 (8), 2427-2433, 2006 | 157 | 2006 |
| Identification of a distinct population of CD133+CXCR4+ cancer stem cells in ovarian cancer M Cioffi, C D’Alterio, R Camerlingo, V Tirino, C Consales, A Riccio, ... Scientific reports 5 (1), 10357, 2015 | 118 | 2015 |
| Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases L Portella, R Vitale, S De Luca, C D’Alterio, C Ierano, M Napolitano, ... PloS one 8 (9), e74548, 2013 | 94 | 2013 |
| CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells C Ieranò, S Santagata, M Napolitano, F Guardia, A Grimaldi, E Antignani, ... Cell death & disease 5 (7), e1310-e1310, 2014 | 91 | 2014 |
| The challenge of exploiting ABCG2 in the clinic R W Robey, C Ierano, Z Zhan, S E Bates Current pharmaceutical biotechnology 12 (4), 595-608, 2011 | 88 | 2011 |
| A novel antagonist of CXCR4 prevents bone marrow-derived mesenchymal stem cell-mediated osteosarcoma and hepatocellular carcinoma cell migration and invasion R Fontanella, A Pelagalli, A Nardelli, C D'Alterio, C Ieranò, L Cerchia, ... Cancer letters 370 (1), 100-107, 2016 | 86 | 2016 |
| Targeting CXCR4 potentiates anti-PD-1 efficacy modifying the tumor microenvironment and inhibiting neoplastic PD-1 C D’Alterio, M Buoncervello, C Ieranò, M Napolitano, L Portella, G Rea, ... Journal of Experimental & Clinical Cancer Research 38, 1-13, 2019 | 80 | 2019 |
| Inhibition of stromal CXCR4 impairs development of lung metastases C D’Alterio, A Barbieri, L Portella, G Palma, M Polimeno, A Riccio, ... Cancer Immunology, Immunotherapy 61, 1713-1720, 2012 | 69 | 2012 |
| Bevacizumab Increases Viral Distribution in Human Anaplastic Thyroid Carcinoma Xenografts and Enhances the Effects of E1A-Defective Adenovirus dl922-947 S Libertini, I Iacuzzo, G Perruolo, S Scala, C Ierano, R Franco, G Hallden, ... Clinical Cancer Research 14 (20), 6505-6514, 2008 | 68 | 2008 |
| CXCR4 and CXCR7 signaling pathways: a focus on the cross-talk between cancer cells and tumor microenvironment S Santagata, C Ieranò, AM Trotta, A Capiluongo, F Auletta, ... Frontiers in oncology 11, 591386, 2021 | 66 | 2021 |
| Epithelial-to-mesenchymal transition in FHC-silenced cells: the role of CXCR4/CXCL12 axis I Aversa, F Zolea, C Ieranò, S Bulotta, AM Trotta, MC Faniello, C De Marco, ... Journal of Experimental & Clinical Cancer Research 36, 1-15, 2017 | 56 | 2017 |
| Histone deacetylase inhibitors influence chemotherapy transport by modulating expression and trafficking of a common polymorphic variant of the ABCG2 efflux transporter A Basseville, A Tamaki, C Ierano, S Trostel, Y Ward, RW Robey, ... Cancer research 72 (14), 3642-3651, 2012 | 56 | 2012 |
| CXCR4 expression affects overall survival of HCC patients whereas CXCR7 expression does not M Neve Polimeno, C Ierano, C D'alterio, N Simona Losito, M Napolitano, ... Cellular & molecular immunology 12 (4), 474-482, 2015 | 55 | 2015 |
| PD-1 blockade delays tumor growth by inhibiting an intrinsic SHP2/Ras/MAPK signalling in thyroid cancer cells F Liotti, N Kumar, N Prevete, M Marotta, D Sorriento, C Ieranò, A Ronchi, ... Journal of Experimental & Clinical Cancer Research 40, 1-16, 2021 | 51 | 2021 |
| CXC chemokine receptor 4 is expressed in uveal malignant melanoma and correlates with the epithelioid-mixed cell type S Scala, C Ieranò, A Ottaiano, R Franco, A La Mura, G Liguori, M Mascolo, ... Cancer Immunology, Immunotherapy 56, 1589-1595, 2007 | 47 | 2007 |
| Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in transmembrane segment 1 of ABCG2 O Polgar, C Ierano, A Tamaki, B Stanley, Y Ward, D Xia, N Tarasova, ... Biochemistry 49 (10), 2235-2245, 2010 | 42 | 2010 |
| Loss of the proteins Bak and Bax prevents apoptosis mediated by histone deacetylase inhibitors C Ieranò, A Chakraborty, A Nicolae, J Bahr, Z Zhan, S Pittaluga, S Bates, ... Cell Cycle 12 (17), 2829-2838, 2013 | 37 | 2013 |
| In PD-1+ human colon cancer cells NIVOLUMAB promotes survival and could protect tumor cells from conventional therapies C Ieranò, D Righelli, C D'Alterio, M Napolitano, L Portella, G Rea, ... Journal for immunotherapy of cancer 10 (3), 2022 | 35 | 2022 |
