Siglec‐15 regulates osteoclast differentiation by modulating RANKL‐induced phosphatidylinositol 3‐kinase/Akt and Erk pathways in association with signaling Adaptor DAP12 Y Kameda, M Takahata, M Komatsu, S Mikuni, S Hatakeyama, T Shimizu, ... Journal of Bone and Mineral Research 28 (12), 2463-2475, 2013 | 108 | 2013 |
Abnormal biomechanics at 6 months are associated with cartilage degeneration at 3 years after anterior cruciate ligament reconstruction T Shimizu, MA Samaan, MS Tanaka, V Pedoia, RB Souza, X Li, CB Ma Arthroscopy: The Journal of Arthroscopic & Related Surgery 35 (2), 511-520, 2019 | 64 | 2019 |
Frequency of teriparatide administration affects the histological pattern of bone formation in young adult male mice T Yamamoto, T Hasegawa, M Sasaki, H Hongo, K Tsuboi, T Shimizu, ... Endocrinology 157 (7), 2604-2620, 2016 | 64 | 2016 |
Siglec-15 is a potential therapeutic target for postmenopausal osteoporosis Y Kameda, M Takahata, S Mikuni, T Shimizu, H Hamano, T Angata, ... Bone 71, 217-226, 2015 | 56 | 2015 |
Assessment of 3-month changes in bone microstructure under anti-TNFα therapy in patients with rheumatoid arthritis using high-resolution peripheral quantitative computed … T Shimizu, HJ Choi, U Heilmeier, M Tanaka, AJ Burghardt, J Gong, ... Arthritis research & therapy 19, 1-11, 2017 | 33 | 2017 |
Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) mediates periarticular bone loss, but not joint destruction, in murine antigen-induced arthritis T Shimizu, M Takahata, Y Kameda, T Endo, H Hamano, S Hiratsuka, ... Bone 79, 65-70, 2015 | 32 | 2015 |
Siglec-15-targeting therapy increases bone mass in rats without impairing skeletal growth D Sato, M Takahata, M Ota, C Fukuda, E Tsuda, T Shimizu, A Okada, ... Bone 116, 172-180, 2018 | 29 | 2018 |
MicroRNA-9 ameliorates destructive arthritis through down-regulation of NF-κB1-RANKL pathway in fibroblast-like synoviocytes WS Lee, S Yasuda, M Kono, Y Kudo, S Shimamura, M Kono, Y Fujieda, ... Clinical immunology 212, 108348, 2020 | 26 | 2020 |
Ectopic RASGRP2 (CalDAG-GEFI) expression in rheumatoid synovium contributes to the development of destructive arthritis H Nakamura, S Shimamura, S Yasuda, M Kono, M Kono, Y Fujieda, ... Annals of the Rheumatic Diseases 77 (12), 1765-1772, 2018 | 25 | 2018 |
Efficacy and safety of osteoporosis medications in a rat model of late-stage chronic kidney disease accompanied by secondary hyperparathyroidism and hyperphosphatemia M Ota, M Takahata, T Shimizu, Y Kanehira, H Kimura-Suda, Y Kameda, ... Osteoporosis International 28, 1481-1490, 2017 | 25 | 2017 |
Vitamin K-dependent carboxylation of osteocalcin affects the efficacy of teriparatide (PTH1–34) for skeletal repair T Shimizu, M Takahata, Y Kameda, H Hamano, T Ito, H Kimura-Suda, ... Bone 64, 95-101, 2014 | 25 | 2014 |
Association of neutrophil extracellular traps with the development of idiopathic osteonecrosis of the femoral head M Nonokawa, T Shimizu, M Yoshinari, Y Hashimoto, Y Nakamura, ... The American Journal of Pathology 190 (11), 2282-2289, 2020 | 23 | 2020 |
Glenoid stress distribution in baseball players using computed tomography osteoabsorptiometry: a pilot study T Shimizu, N Iwasaki, K Nishida, A Minami, T Funakoshi Clinical Orthopaedics and Related Research® 470 (6), 1534-1539, 2012 | 22 | 2012 |
Blockade of XCL1/lymphotactin ameliorates severity of periprosthetic osteolysis triggered by polyethylene-particles Y Tian, MA Terkawi, T Onodera, H Alhasan, G Matsumae, D Takahashi, ... Frontiers in immunology 11, 1720, 2020 | 21 | 2020 |
Ras guanine nucleotide–releasing protein 4 is aberrantly expressed in the fibroblast‐like synoviocytes of patients with rheumatoid arthritis and controls their proliferation M Kono, S Yasuda, RL Stevens, H Koide, T Kurita, Y Shimizu, ... Arthritis & Rheumatology 67 (2), 396-407, 2015 | 19 | 2015 |
Breast cancer cells expressing cancer-associated sialyl-Tn antigen have less capacity to develop osteolytic lesions in a mouse model of skeletal colonization R Fujita, H Hamano, Y Kameda, R Arai, T Shimizu, M Ota, D Sato, ... Clinical & Experimental Metastasis 36, 539-549, 2019 | 18 | 2019 |
Effects after starting or switching from bisphosphonate to romosozumab or denosumab in Japanese postmenopausal patients T Shimizu, K Arita, E Murota, S Hiratsuka, R Fujita, H Ishizu, T Asano, ... Journal of Bone and Mineral Metabolism 39, 868-875, 2021 | 16 | 2021 |
Teriparatide improves trabecular osteoporosis but simultaneously promotes ankylosis of the spine in the Twy mouse model for diffuse idiopathic skeletal hyperostosis H Hamano, M Takahata, M Ota, S Hiratsuka, T Shimizu, Y Kameda, ... Calcified tissue international 98, 140-148, 2016 | 16 | 2016 |
Structural changes over a short period are associated with functional assessments in rheumatoid arthritis T Shimizu, A Cruz, M Tanaka, K Mamoto, V Pedoia, AJ Burghardt, ... The Journal of rheumatology 46 (7), 676-684, 2019 | 15 | 2019 |
Optimal administration frequency and dose of teriparatide for acceleration of biomechanical healing of long-bone fracture in a mouse model M Ota, M Takahata, T Shimizu, D Momma, H Hamano, S Hiratsuka, ... Journal of Bone and Mineral Metabolism 37, 256-263, 2019 | 15 | 2019 |