| Comment on" Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake" N Chartrel, R Alvear-Perez, J Leprince, X Iturrioz, ARL Goazigo, V Audinot, ... science 315 (5813), 766-766, 2007 | 289 | 2007 |
| Functional dissociation of apelin receptor signaling and endocytosis: implications for the effects of apelin on arterial blood pressure SE Messari, X Iturrioz, C Fassot, N De Mota, D Roesch, C Llorens‐Cortes Journal of neurochemistry 90 (6), 1290-1301, 2004 | 216 | 2004 |
| Reciprocal regulation of plasma apelin and vasopressin by osmotic stimuli M Azizi, X Iturrioz, A Blanchard, N De Mota, N Chartrel, H Vaudry, ... Journal of the American Society of Nephrology 19 (5), 1015-1024, 2008 | 175 | 2008 |
| Identification and pharmacological properties of E339–3D6, the first nonpeptidic apelin receptor agonist X Iturrioz, R Alvear‐Perez, N De Mota, C Franchet, F Guillier, V Leroux, ... The FASEB Journal 24 (5), 1506-1517, 2010 | 128 | 2010 |
| Beta 1-integrin–c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes R Barrow-McGee, N Kishi, C Joffre, L Ménard, A Hervieu, BA Bakhouche, ... Nature communications 7 (1), 11942, 2016 | 113 | 2016 |
| A glutamate residue contributes to the exopeptidase specificity in aminopeptidase A G Vazeux, X Iturrioz, P Corvol, C Llorens-Cortes Biochemical Journal 334 (2), 407-413, 1998 | 98 | 1998 |
| A new strategy for treating hypertension by blocking the activity of the brain renin–angiotensin system with aminopeptidase A inhibitors J Gao, Y Marc, X Iturrioz, V Leroux, F Balavoine, C Llorens-Cortes Clinical science 127 (3), 135-148, 2014 | 96 | 2014 |
| By interacting with the C-terminal Phe of apelin, Phe255 and Trp259 in helix VI of the apelin receptor are critical for internalization X Iturrioz, R Gerbier, V Leroux, R Alvear-Perez, B Maigret, ... Journal of Biological Chemistry 285 (42), 32627-32637, 2010 | 92 | 2010 |
| Biased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the C-terminal phenylalanine E Ceraudo, C Galanth, E Carpentier, I Banegas-Font, AM Schonegge, ... Journal of Biological Chemistry 289 (35), 24599-24610, 2014 | 79 | 2014 |
| Aminopeptidase A, which generates one of the main effector peptides of the brain renin-angiotensin system, angiotensin III, has a key role in central control of arterial blood … A Reaux, X Iturrioz, G Vazeux, MC Fournie-Zaluski, C David, BP Roques, ... Biochemical Society Transactions 28 (4), 435-440, 2000 | 79 | 2000 |
| A tyrosine residue essential for catalytic activity in aminopeptidase A G Vazeux, X Iturrioz, P Corvol, C Llorens-Cortès Biochemical Journal 327 (3), 883-889, 1997 | 79 | 1997 |
| The apelinergic system: a perspective on challenges and opportunities in cardiovascular and metabolic disorders E Marsault, C Llorens‐Cortes, X Iturrioz, HJ Chun, O Lesur, GY Oudit, ... Annals of the New York Academy of Sciences 1455 (1), 12-33, 2019 | 68 | 2019 |
| Development of original metabolically stable apelin‐17 analogs with diuretic and cardiovascular effects R Gerbier, R Alvear‐Perez, JF Margathe, A Flahault, P Couvineau, J Gao, ... The FASEB Journal 31 (2), 687-700, 2017 | 67 | 2017 |
| New structural insights into the apelin receptor: identification of key residues for apelin binding R Gerbier, V Leroux, P Couvineau, R Alvear‐Perez, B Maigret, ... The FASEB Journal 29 (1), 314-322, 2015 | 61 | 2015 |
| Study of asparagine 353 in aminopeptidase A: characterization of a novel motif (GXMEN) implicated in exopeptidase specificity of monozinc aminopeptidases X Iturrioz, R Rozenfeld, A Michaud, P Corvol, C Llorens-Cortes Biochemistry 40 (48), 14440-14448, 2001 | 61 | 2001 |
| Phosphorylation is required for PMA-and cell-cycle-induced degradation of protein kinase Cδ J Srivastava, KJ Procyk, X Iturrioz, PJ Parker Biochemical Journal 368 (1), 349-355, 2002 | 60 | 2002 |
| SDHD Immunohistochemistry: A New Tool to Validate SDHx Mutations in Pheochromocytoma/Paraganglioma M Menara, L Oudijk, C Badoual, J Bertherat, C Lepoutre-Lussey, L Amar, ... The Journal of Clinical Endocrinology & Metabolism 100 (2), E287-E291, 2015 | 59 | 2015 |
| Phosphoprotein enriched in astrocytes-15 kDa expression inhibits astrocyte migration by a protein kinase Cδ-dependent mechanism F Renault-Mihara, F Beuvon, X Iturrioz, B Canton, S De Bouard, ... Molecular biology of the cell 17 (12), 5141-5152, 2006 | 55 | 2006 |
| Contribution of molecular modeling and site-directed mutagenesis to the identification of a new residue, glutamate 215, involved in the exopeptidase specificity of aminopeptidase A R Rozenfeld, X Iturrioz, M Okada, B Maigret, C Llorens-Cortes Biochemistry 42 (50), 14785-14793, 2003 | 53 | 2003 |
| Structure–activity relationship studies toward the discovery of selective apelin receptor agonists JF Margathe, X Iturrioz, R Alvear-Perez, C Marsol, S Riche, H Chabane, ... Journal of medicinal chemistry 57 (7), 2908-2919, 2014 | 52 | 2014 |
