Alkoxycarbonate ester prodrugs of preclinical drug candidate ELQ-300 for prophylaxis and treatment of malaria L Frueh, Y Li, MW Mather, Q Li, S Pou, A Nilsen, RW Winter, IP Forquer, ... ACS infectious diseases 3 (10), 728-735, 2017 | 38 | 2017 |
Improving solubility and oral bioavailability of a novel antimalarial prodrug: comparing spray-dried dispersions with self-emulsifying drug delivery systems S Potharaju, SK Mutyam, M Liu, C Green, L Frueh, A Nilsen, S Pou, ... Pharmaceutical development and technology 25 (5), 625-639, 2020 | 23 | 2020 |
Characterization and structure-activity relationship analysis of a class of antiviral compounds that directly bind dengue virus capsid protein and are incorporated into virions JL Smith, K Sheridan, CJ Parkins, L Frueh, AL Jemison, K Strode, G Dow, ... Antiviral research 155, 12-19, 2018 | 23 | 2018 |
ELQ-331 as a prototype for extremely durable chemoprotection against malaria MJ Smilkstein, S Pou, A Krollenbrock, LA Bleyle, RA Dodean, L Frueh, ... Malaria journal 18 (1), 1-17, 2019 | 21 | 2019 |
Outpatient treatment of low‐risk pulmonary embolism in the era of direct oral anticoagulants: a systematic review BC Maughan, L Frueh, MS McDonagh, B Casciere, JA Kline Academic Emergency Medicine 28 (2), 226-239, 2021 | 17 | 2021 |
Effective Therapy Targeting Cytochrome bc1 Prevents Babesia Erythrocytic Development and Protects from Lethal Infection JE Chiu, I Renard, AC Pal, P Singh, P Vydyam, J Thekkiniath, M Kumar, ... Antimicrobial agents and chemotherapy 65 (9), 10.1128/aac. 00662-21, 2021 | 15 | 2021 |
Branched-chain amino acids and risk of breast cancer OA Zeleznik, R Balasubramanian, Y Ren, DK Tobias, BA Rosner, C Peng, ... JNCI cancer spectrum 5 (5), pkab059, 2021 | 14 | 2021 |
Circulating amino acids and amino acid-related metabolites and risk of breast cancer among predominantly premenopausal women OA Zeleznik, R Balasubramanian, Y Zhao, L Frueh, S Jeanfavre, ... NPJ breast cancer 7 (1), 54, 2021 | 14 | 2021 |
Babesia duncani as a Model Organism to Study the Development, Virulence, and Drug Susceptibility of Intraerythrocytic Parasites In Vitro and In Vivo AC Pal, I Renard, P Singh, P Vydyam, JE Chiu, S Pou, RW Winter, ... The Journal of infectious diseases 226 (7), 1267-1275, 2022 | 11 | 2022 |
New Scalable Synthetic Routes to ELQ-300, ELQ-316, and Other Antiparasitic Quinolones S Pou, RA Dodean, L Frueh, KM Liebman, RT Gallagher, H Jin, ... Organic Process Research & Development 25 (8), 1841-1852, 2021 | 10 | 2021 |
Drug use behaviors, trauma, and emotional affect following the overdose of a social network member: A qualitative investigation A Macmadu, L Frueh, AB Collins, R Newman, NP Barnett, JD Rich, ... International Journal of Drug Policy 107, 103792, 2022 | 5 | 2022 |
Cohort study of race/ethnicity and incident primary open-angle glaucoma characterized by autonomously determined visual field loss patterns JH Kang, M Wang, L Frueh, B Rosner, JL Wiggs, T Elze, LR Pasquale Translational vision science & technology 11 (7), 21-21, 2022 | 4 | 2022 |
Multi-level influences on increased overdose risk behaviors during the COVID-19 pandemic among people who use drugs in Rhode Island: a qualitative investigation L Frueh, AB Collins, R Newman, NP Barnett, JD Rich, MA Clark, ... Harm Reduction Journal 20 (1), 14, 2023 | 2 | 2023 |
Characteristics of events in which police responded to overdoses: an examination of incident reports in Rhode Island A Macmadu, A Yolken, L Frueh, JR Toussaint, R Newman, BP Jacka, ... Harm Reduction Journal 19 (1), 116, 2022 | 2 | 2022 |
Pregnancy urinary concentrations of bisphenol A, parabens and other phenols in relation to serum levels of lipid biomarkers: Results from the EARTH study L Mínguez-Alarcón, L Frueh, PL Williams, T James-Todd, I Souter, ... Science of The Total Environment 833, 155191, 2022 | 2 | 2022 |
Prediagnostic Plasma Metabolomics and the Risk of Exfoliation Glaucoma JH Kang, O Zeleznik, L Frueh, J Lasky-Su, AH Eliassen, C Clish, ... Investigative ophthalmology & visual science 63 (9), 15-15, 2022 | 2 | 2022 |
Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank OA Zeleznik, JH Kang, J Lasky-Su, AH Eliassen, L Frueh, CB Clish, ... Nature Communications 14 (1), 2860, 2023 | 1 | 2023 |
Association of Plasma Metabolomic Biomarkers With Persistent Tinnitus: A Population-Based Case-Control Study OA Zeleznik, DB Welling, K Stankovic, L Frueh, R Balasubramanian, ... JAMA Otolaryngology–Head & Neck Surgery 149 (5), 404-415, 2023 | 1 | 2023 |
Plasma metabolomics of primary open-angle glaucoma in three prospective US cohorts and the UK Biobank. O Zeleznik, JH Kang, JA Lasky-Su, AH Eliassen, L Frueh, C Clish, ... medRxiv, 2022.02. 24.22271483, 2022 | 1 | 2022 |
Circulating amino acids, amino acid metabolites, dipeptides, and other cationic metabolites and risk of breast cancer OA Zeleznik, R Balasubramanian, Y Zhao, L Frueh, S Jeanfavre, ... medRxiv, 2020.09. 01.20185835, 2020 | 1 | 2020 |