Fatty acid synthesis is required for breast cancer brain metastasis GB Ferraro, A Ali, A Luengo, DP Kodack, A Deik, KL Abbott, D Bezwada, ... Nature cancer 2 (4), 414-428, 2021 | 223 | 2021 |
Neural precursor-derived pleiotrophin mediates subventricular zone invasion by glioma EY Qin, DD Cooper, KL Abbott, J Lennon, S Nagaraja, A Mackay, C Jones, ... Cell 170 (5), 845-859. e19, 2017 | 214 | 2017 |
The CEP19-RABL2 GTPase complex binds IFT-B to initiate intraflagellar transport at the ciliary base T Kanie, KL Abbott, NA Mooney, ED Plowey, J Demeter, PK Jackson Developmental cell 42 (1), 22-36. e12, 2017 | 117 | 2017 |
Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer A Luengo, KL Abbott, SM Davidson, AM Hosios, B Faubert, SH Chan, ... Nature communications 10 (1), 5604, 2019 | 57 | 2019 |
Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited Z Li, BW Ji, PD Dixit, K Tchourine, EC Lien, AM Hosios, KL Abbott, ... Nature metabolism 4 (6), 711-723, 2022 | 45* | 2022 |
Manipulating mitochondrial electron flow enhances tumor immunogenicity KC Mangalhara, SK Varanasi, MA Johnson, MJ Burns, GR Rojas, ... Science 381 (6664), 1316-1323, 2023 | 43 | 2023 |
Combined proteomic and genetic interaction mapping reveals new RAS effector pathways and susceptibilities MR Kelly, K Kostyrko, K Han, NA Mooney, EE Jeng, K Spees, PT Dinh, ... Cancer discovery 10 (12), 1950-1967, 2020 | 36 | 2020 |
Screening in serum-derived medium reveals differential response to compounds targeting metabolism KL Abbott, A Ali, D Casalena, BT Do, R Ferreira, JH Cheah, CK Soule, ... Cell chemical biology 30 (9), 1156-1168. e7, 2023 | 15 | 2023 |
Cancer tissue of origin constrains the growth and metabolism of metastases S Sivanand, Y Gultekin, PS Winter, SY Vermeulen, KM Tchourine, ... Nature Metabolism 6 (9), 1668-1681, 2024 | 9 | 2024 |
Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening A Ramos, CE Koch, Y Liu-Lupo, RD Hellinger, T Kyung, KL Abbott, ... Nature Communications 14 (1), 8048, 2023 | 8 | 2023 |
Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress BT Do, PP Hsu, SY Vermeulen, Z Wang, T Hirz, KL Abbott, N Aziz, ... Developmental Cell, 2024 | 7 | 2024 |
Differential substrate use in EGF‐and oncogenic KRAS‐stimulated human mammary epithelial cells MA Keibler, W Dong, KD Korthauer, AM Hosios, SJ Moon, LB Sullivan, ... The FEBS journal 288 (19), 5629-5649, 2021 | 5 | 2021 |
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability KL Abbott, A Ali, BI Reinfeld, A Deik, S Subudhi, MD Landis, RA Hongo, ... Elife 13, RP95652, 2024 | 1 | 2024 |
Myristoylated Neuronal Calcium Sensor-1 captures the ciliary vesicle at distal appendages T Kanie, R Ng, KL Abbott, O Pongs, PK Jackson bioRxiv, 2023 | 1 | 2023 |
The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients KL Abbott, MG Vander Heiden BMC biology 19 (1), 92, 2021 | 1 | 2021 |
Site of breast cancer metastasis is independent of single nutrient levels KL Abbott, S Subudhi, R Ferreira, Y Gültekin, SC Steinbuch, MB Munim, ... bioRxiv, 2024.10. 24.616714, 2024 | | 2024 |