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Bryce Carey
Bryce Carey
Vertex Cell & Genetic Therapies
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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
M Guttman, I Amit, M Garber, C French, MF Lin, D Feldser, M Huarte, ...
Nature 458 (7235), 223-227, 2009
48432009
Histone H3K27ac separates active from poised enhancers and predicts developmental state
MP Creyghton, AW Cheng, GG Welstead, T Kooistra, BW Carey, ...
Proceedings of the National Academy of Sciences 107 (50), 21931-21936, 2010
44572010
lincRNAs act in the circuitry controlling pluripotency and differentiation
M Guttman, J Donaghey, BW Carey, M Garber, JK Grenier, G Munson, ...
Nature 477 (7364), 295-300, 2011
21832011
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency
J Hanna, S Markoulaki, P Schorderet, BW Carey, C Beard, M Wernig, ...
cell 133 (2), 250-264, 2008
11452008
Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs
J Hanna, AW Cheng, K Saha, J Kim, CJ Lengner, F Soldner, JP Cassady, ...
Proceedings of the National Academy of Sciences 107 (20), 9222-9227, 2010
10232010
Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
BW Carey, LWS Finley, JR Cross, CD Allis, CB Thompson
Nature 518 (7539), 413-416, 2015
9292015
Reprogramming of murine and human somatic cells using a single polycistronic vector
BW Carey, S Markoulaki, J Hanna, K Saha, Q Gao, M Mitalipova, ...
Proceedings of the National Academy of Sciences 106 (1), 157-162, 2009
7002009
Metastable pluripotent states in NOD-mouse-derived ESCs
J Hanna, S Markoulaki, M Mitalipova, AW Cheng, JP Cassady, J Staerk, ...
Cell stem cell 4 (6), 513-524, 2009
4122009
Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells
BW Carey, S Markoulaki, JH Hanna, DA Faddah, Y Buganim, J Kim, ...
Cell stem cell 9 (6), 588-598, 2011
4032011
BACE1 regulates voltage-gated sodium channels and neuronal activity
DY Kim, BW Carey, H Wang, LAM Ingano, AM Binshtok, MH Wertz, ...
Nature cell biology 9 (7), 755-764, 2007
3842007
Single-gene transgenic mouse strains for reprogramming adult somatic cells
BW Carey, S Markoulaki, C Beard, J Hanna, R Jaenisch
Nature methods 7 (1), 56-59, 2010
2452010
Presenilin/γ-secretase-mediated cleavage of the voltage-gated sodium channel β2-subunit regulates cell adhesion and migration
DY Kim, LAMK Ingano, BW Carey, WH Pettingell, DM Kovacs
Journal of Biological Chemistry 280 (24), 23251-23261, 2005
1882005
Transgenic mice with defined combinations of drug-inducible reprogramming factors
S Markoulaki, J Hanna, C Beard, BW Carey, AW Cheng, CJ Lengner, ...
Nature biotechnology 27 (2), 169-171, 2009
1252009
Presenilin/γ-secretase-mediated cleavage regulates association of leukocyte-common antigen-related (LAR) receptor tyrosine phosphatase with β-catenin
A Haapasalo, DY Kim, BW Carey, MK Turunen, WH Pettingell, DM Kovacs
Journal of Biological Chemistry 282 (12), 9063-9072, 2007
612007
ZBTB1 regulates asparagine synthesis and leukemia cell response to L-asparaginase
RT Williams, R Guarecuco, LA Gates, D Barrows, MC Passarelli, B Carey, ...
Cell metabolism 31 (4), 852-861. e6, 2020
552020
Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity
LWS Finley, SA Vardhana, BW Carey, D Alonso-Curbelo, R Koche, ...
Nature cell biology 20 (5), 565-574, 2018
522018
Glutamine independence is a selectable feature of pluripotent stem cells
SA Vardhana, PK Arnold, BP Rosen, Y Chen, BW Carey, D Huangfu, ...
Nature metabolism 1 (7), 676-687, 2019
512019
Presenilin/γ-secretase and α-secretase-like peptidases cleave human MHC Class I proteins
BW Carey, DY Kim, DM Kovacs
Biochemical Journal 401 (1), 121-127, 2007
502007
Reprogramming of somatic cell identity
J Hanna, BW Carey, R Jaenisch
Cold Spring Harbor symposia on quantitative biology 73, 147-155, 2008
452008
Nucleic acid constructs encoding reprogramming factors linked by self-cleaving peptides
R Jaenisch, BW Carey
US Patent 9,497,943, 2016
262016
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