Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration SE Klompe, PLH Vo, TS Halpin-Healy, SH Sternberg Nature 571 (7764), 219-225, 2019 | 529 | 2019 |
CRISPR RNA-guided integrases for high-efficiency, multiplexed bacterial genome engineering PLH Vo, C Ronda, SE Klompe, EE Chen, C Acree, HH Wang, ... Nature biotechnology 39 (4), 480-489, 2021 | 235 | 2021 |
Harnessing type I CRISPR–Cas systems for genome engineering in human cells P Cameron, MM Coons, SE Klompe, AM Lied, SC Smith, B Vidal, ... Nature biotechnology 37 (12), 1471-1477, 2019 | 113 | 2019 |
Structural basis of DNA targeting by a transposon-encoded CRISPR–Cas system TS Halpin-Healy, SE Klompe, SH Sternberg, IS Fernández Nature 577 (7789), 271-274, 2020 | 106 | 2020 |
Harnessing “A Billion Years of Experimentation”: the ongoing exploration and exploitation of CRISPR–Cas immune systems SE Klompe, SH Sternberg The CRISPR journal 1 (2), 141-158, 2018 | 55 | 2018 |
Engineered cascade components and cascade complexes PS Cameron, SE Klompe, SH Stemberg US Patent 10,227,576, 2019 | 47 | 2019 |
Evolutionary and mechanistic diversity of Type IF CRISPR-associated transposons SE Klompe, N Jaber, LY Beh, JT Mohabir, A Bernheim, SH Sternberg Molecular cell 82 (3), 616-628. e5, 2022 | 46 | 2022 |
Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases GD Lampe, RT King, TS Halpin-Healy, SE Klompe, MI Hogan, PLH Vo, ... Nature biotechnology 42 (1), 87-98, 2024 | 45 | 2024 |
Shooting the messenger: RNA-targetting CRISPR-Cas systems Y Zhu, SE Klompe, M Vlot, J van der Oost, RHJ Staals Bioscience reports 38 (3), BSR20170788, 2018 | 37 | 2018 |
Novel molecular requirements for CRISPR RNA-guided transposition MWG Walker, SE Klompe, DJ Zhang, SH Sternberg Nucleic Acids Research 51 (9), 4519-4535, 2023 | 12 | 2023 |
Engineered cascade components and cascade complexes PS Cameron, SE Klompe, SH Sternberg US Patent 10,781,432, 2020 | 11 | 2020 |
Engineered cascade components and cascade complexes PS Cameron, SD Gradia, SE Klompe, SH Sternberg, MS Thompson US Patent App. 17/120,081, 2021 | 9 | 2021 |
Transposon mutagenesis libraries reveal novel molecular requirements during CRISPR RNA-guided DNA integration MWG Walker, SE Klompe, DJ Zhang, SH Sternberg bioRxiv, 2023 | 8 | 2023 |
Engineered cascade components and cascade complexes PS Cameron, SE Klompe, SH Sternberg US Patent 10,329,547, 2019 | 4 | 2019 |
Bacterial genome engineering using CRISPR RNA-guided transposases DR Gelsinger, PLH Vo, SE Klompe, C Ronda, H Wang, SH Sternberg bioRxiv, 2023 | 3 | 2023 |
Publisher Correction: Structural basis of DNA targeting by a transposon-encoded CRISPR–Cas system TS Halpin-Healy, SE Klompe, SH Sternberg, IS Fernandez Nature 585 (7825), E12-E12, 2020 | 2 | 2020 |
Engineered cascade components and cascade complexes PS Cameron, SE Klompe, SH Sternberg US Patent 10,457,922, 2019 | 2 | 2019 |
Bacterial genome engineering using CRISPR-associated transposases DR Gelsinger, PLH Vo, SE Klompe, C Ronda, HH Wang, SH Sternberg Nature Protocols 19 (3), 752-790, 2024 | 1 | 2024 |
Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases GD Lampe, RT King, TS Halpin-Healy, SE Klompe, MI Hogan, PLH Vo, ... bioRxiv, 2023 | 1 | 2023 |
Engineered cascade components and cascade complexes PS Cameron, SE Klompe, SH Sternberg US Patent 11,555,181, 2023 | 1 | 2023 |