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Jon M Steichen
Jon M Steichen
在 scripps.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
HIV vaccine design to target germline precursors of glycan-dependent broadly neutralizing antibodies
JM Steichen, DW Kulp, T Tokatlian, A Escolano, P Dosenovic, ...
Immunity 45 (3), 483-496, 2016
3782016
Sequential immunization elicits broadly neutralizing anti-HIV-1 antibodies in Ig knockin mice
A Escolano, JM Steichen, P Dosenovic, DW Kulp, J Golijanin, D Sok, ...
Cell 166 (6), 1445-1458. e12, 2016
3232016
PKA: lessons learned after twenty years
SS Taylor, P Zhang, JM Steichen, MM Keshwani, AP Kornev
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (7), 1271-1278, 2013
3142013
Elicitation of robust tier 2 neutralizing antibody responses in nonhuman primates by HIV envelope trimer immunization using optimized approaches
M Pauthner, C Havenar-Daughton, D Sok, JP Nkolola, R Bastidas, ...
Immunity 46 (6), 1073-1088. e6, 2017
3012017
Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers
T Tokatlian, BJ Read, CA Jones, DW Kulp, S Menis, JYH Chang, ...
Science 363 (6427), 649-654, 2019
2542019
Evolution of the eukaryotic protein kinases as dynamic molecular switches
SS Taylor, MM Keshwani, JM Steichen, AP Kornev
Philosophical Transactions of the Royal Society B: Biological Sciences 367 …, 2012
2542012
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses
JM Steichen, YC Lin, C Havenar-Daughton, S Pecetta, G Ozorowski, ...
Science 366 (6470), eaax4380, 2019
1852019
Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding
DW Kulp, JM Steichen, M Pauthner, X Hu, T Schiffner, A Liguori, ...
Nature communications 8 (1), 1655, 2017
1442017
Structural basis for the regulation of protein kinase A by activation loop phosphorylation
JM Steichen, M Kuchinskas, MM Keshwani, J Yang, JA Adams, SS Taylor
Journal of Biological Chemistry 287 (18), 14672-14680, 2012
1082012
Global Consequences of Activation Loop Phosphorylation on Protein Kinase A 2
JM Steichen, GH Iyer, S Li, SA Saldanha, MS Deal, VL Woods, SS Taylor
Journal of biological chemistry 285 (6), 3825-3832, 2010
1032010
Phosphoryl transfer by protein kinase A is captured in a crystal lattice
AC Bastidas, MS Deal, JM Steichen, Y Guo, J Wu, SS Taylor
Journal of the American Chemical Society 135 (12), 4788-4798, 2013
932013
The Role of Cytosolic α-Glucan Phosphorylase in Maltose Metabolism and the Comparison of Amylomaltase in Arabidopsis and Escherichia coli
Y Lu, JM Steichen, J Yao, TD Sharkey
Plant physiology 142 (3), 878-889, 2006
782006
Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses
JMJ Tas, JH Koo, YC Lin, Z Xie, JM Steichen, AM Jackson, BM Hauser, ...
Immunity 55 (10), 1856-1871. e6, 2022
702022
Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase
AC Bastidas, MS Deal, JM Steichen, MM Keshwani, Y Guo, SS Taylor
Journal of molecular biology 422 (2), 215-229, 2012
692012
Domain characterization of a 4-α-glucanotransferase essential for maltose metabolism in photosynthetic leaves
JM Steichen, RV Petty, TD Sharkey
Journal of biological chemistry 283 (30), 20797-20804, 2008
522008
Cellular and organ level localization of maltose in maltose-excess Arabidopsis mutants
Y Lu, JM Steichen, SE Weise, TD Sharkey
Planta 224, 935-943, 2006
482006
A conserved Glu–Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold
J Yang, J Wu, JM Steichen, AP Kornev, MS Deal, S Li, B Sankaran, ...
Journal of molecular biology 415 (4), 666-679, 2012
462012
One‐step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock‐in mice
YC Lin, S Pecetta, JM Steichen, S Kratochvil, E Melzi, J Arnold, ...
The EMBO journal 37 (18), e99243, 2018
362018
Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors
JR Willis, ZT Berndsen, KM Ma, JM Steichen, T Schiffner, E Landais, ...
Immunity 55 (11), 2149-2167. e9, 2022
232022
Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice
E Melzi, JR Willis, KM Ma, YC Lin, S Kratochvil, ZT Berndsen, EA Landais, ...
Immunity 55 (11), 2168-2186. e6, 2022
202022
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