HIV vaccine design to target germline precursors of glycan-dependent broadly neutralizing antibodies JM Steichen, DW Kulp, T Tokatlian, A Escolano, P Dosenovic, ... Immunity 45 (3), 483-496, 2016 | 378 | 2016 |
Sequential immunization elicits broadly neutralizing anti-HIV-1 antibodies in Ig knockin mice A Escolano, JM Steichen, P Dosenovic, DW Kulp, J Golijanin, D Sok, ... Cell 166 (6), 1445-1458. e12, 2016 | 323 | 2016 |
PKA: lessons learned after twenty years SS Taylor, P Zhang, JM Steichen, MM Keshwani, AP Kornev Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (7), 1271-1278, 2013 | 314 | 2013 |
Elicitation of robust tier 2 neutralizing antibody responses in nonhuman primates by HIV envelope trimer immunization using optimized approaches M Pauthner, C Havenar-Daughton, D Sok, JP Nkolola, R Bastidas, ... Immunity 46 (6), 1073-1088. e6, 2017 | 301 | 2017 |
Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers T Tokatlian, BJ Read, CA Jones, DW Kulp, S Menis, JYH Chang, ... Science 363 (6427), 649-654, 2019 | 254 | 2019 |
Evolution of the eukaryotic protein kinases as dynamic molecular switches SS Taylor, MM Keshwani, JM Steichen, AP Kornev Philosophical Transactions of the Royal Society B: Biological Sciences 367 …, 2012 | 254 | 2012 |
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses JM Steichen, YC Lin, C Havenar-Daughton, S Pecetta, G Ozorowski, ... Science 366 (6470), eaax4380, 2019 | 185 | 2019 |
Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding DW Kulp, JM Steichen, M Pauthner, X Hu, T Schiffner, A Liguori, ... Nature communications 8 (1), 1655, 2017 | 144 | 2017 |
Structural basis for the regulation of protein kinase A by activation loop phosphorylation JM Steichen, M Kuchinskas, MM Keshwani, J Yang, JA Adams, SS Taylor Journal of Biological Chemistry 287 (18), 14672-14680, 2012 | 108 | 2012 |
Global Consequences of Activation Loop Phosphorylation on Protein Kinase A 2 JM Steichen, GH Iyer, S Li, SA Saldanha, MS Deal, VL Woods, SS Taylor Journal of biological chemistry 285 (6), 3825-3832, 2010 | 103 | 2010 |
Phosphoryl transfer by protein kinase A is captured in a crystal lattice AC Bastidas, MS Deal, JM Steichen, Y Guo, J Wu, SS Taylor Journal of the American Chemical Society 135 (12), 4788-4798, 2013 | 93 | 2013 |
The Role of Cytosolic α-Glucan Phosphorylase in Maltose Metabolism and the Comparison of Amylomaltase in Arabidopsis and Escherichia coli Y Lu, JM Steichen, J Yao, TD Sharkey Plant physiology 142 (3), 878-889, 2006 | 78 | 2006 |
Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses JMJ Tas, JH Koo, YC Lin, Z Xie, JM Steichen, AM Jackson, BM Hauser, ... Immunity 55 (10), 1856-1871. e6, 2022 | 70 | 2022 |
Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase AC Bastidas, MS Deal, JM Steichen, MM Keshwani, Y Guo, SS Taylor Journal of molecular biology 422 (2), 215-229, 2012 | 69 | 2012 |
Domain characterization of a 4-α-glucanotransferase essential for maltose metabolism in photosynthetic leaves JM Steichen, RV Petty, TD Sharkey Journal of biological chemistry 283 (30), 20797-20804, 2008 | 52 | 2008 |
Cellular and organ level localization of maltose in maltose-excess Arabidopsis mutants Y Lu, JM Steichen, SE Weise, TD Sharkey Planta 224, 935-943, 2006 | 48 | 2006 |
A conserved Glu–Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold J Yang, J Wu, JM Steichen, AP Kornev, MS Deal, S Li, B Sankaran, ... Journal of molecular biology 415 (4), 666-679, 2012 | 46 | 2012 |
One‐step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock‐in mice YC Lin, S Pecetta, JM Steichen, S Kratochvil, E Melzi, J Arnold, ... The EMBO journal 37 (18), e99243, 2018 | 36 | 2018 |
Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors JR Willis, ZT Berndsen, KM Ma, JM Steichen, T Schiffner, E Landais, ... Immunity 55 (11), 2149-2167. e9, 2022 | 23 | 2022 |
Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice E Melzi, JR Willis, KM Ma, YC Lin, S Kratochvil, ZT Berndsen, EA Landais, ... Immunity 55 (11), 2168-2186. e6, 2022 | 20 | 2022 |