Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13331* | 2021 |
Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization TJ Sargeant, B Lloyd-Lewis, HK Resemann, A Ramos-Montoya, ... Nature cell biology 16 (11), 1057-1068, 2014 | 171 | 2014 |
Endo‐lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease? LS Whyte, AA Lau, KM Hemsley, JJ Hopwood, TJ Sargeant Journal of neurochemistry 140 (5), 703-717, 2017 | 151 | 2017 |
Retromer has a selective function in cargo sorting via endosome transport carriers. Y Cui, JM Carosi, Z Yang, N Ariotti, MC Kerr, RG Parton, TJ Sargeant, ... Journal of Cell Biology, 2019 | 140 | 2019 |
Opioidergic regulation of astroglial/neuronal proliferation: where are we now? TJ Sargeant, JH Miller, DJ Day Journal of neurochemistry 107 (4), 883-897, 2008 | 90 | 2008 |
Rapamycin and Alzheimer disease: a double-edged sword? JM Carosi, TJ Sargeant Autophagy, 2019 | 82 | 2019 |
Genetic variation within endolysosomal system is associated with late-onset Alzheimer’s disease S Gao, AE Casey, TJ Sargeant, VP Mäkinen Brain 141 (9), 2711-2720, 2018 | 71 | 2018 |
Reduction in open field activity in the absence of memory deficits in the AppNL− G− F knock-in mouse model of Alzheimer’s disease LS Whyte, KM Hemsley, AA Lau, S Hassiotis, T Saito, TC Saido, ... Behavioural brain research 336, 177-181, 2018 | 68 | 2018 |
Autophagy modulation as a treatment of amyloid diseases Z Mputhia, E Hone, T Tripathi, T Sargeant, R Martins, P Bharadwaj Molecules 24 (18), 3372, 2019 | 60 | 2019 |
Adeno-associated virus-mediated expression of β-hexosaminidase prevents neuronal loss in the Sandhoff mouse brain TJ Sargeant, S Wang, J Bradley, NJC Smith, AA Raha, R McNair, ... Human molecular genetics 20 (22), 4371-4380, 2011 | 54 | 2011 |
Intermittent fasting plus early time-restricted eating versus calorie restriction and standard care in adults at risk of type 2 diabetes: a randomized controlled trial XT Teong, K Liu, AD Vincent, J Bensalem, B Liu, KJ Hattersley, L Zhao, ... Nature Medicine 29 (4), 963-972, 2023 | 45 | 2023 |
The mTOR–lysosome axis at the centre of ageing JM Carosi, C Fourrier, J Bensalem, TJ Sargeant FEBS Open Bio 12 (4), 739-757, 2022 | 44 | 2022 |
Acute in utero morphine exposure slows G2 / M phase transition in radial glial and basal progenitor cells in the dorsal telencephalon of the E15.5 embryonic … TJ Sargeant, DJ Day, JH Miller, RWJ Steel European Journal of Neuroscience 28 (6), 1060-1067, 2008 | 42 | 2008 |
The composition of the gut microbiota following early-life antibiotic exposure affects host health and longevity in later life MA Lynn, G Eden, FJ Ryan, J Bensalem, X Wang, SJ Blake, JM Choo, ... Cell Reports 36 (8), 2021 | 39 | 2021 |
Lysosomal LAMP 1 immunoreactivity exists in both diffuse and neuritic amyloid plaques in the human hippocampus S Hassiotis, J Manavis, PC Blumbergs, KJ Hattersley, JM Carosi, M Kamei, ... European Journal of Neuroscience 47 (9), 1043-1053, 2018 | 39 | 2018 |
Retromer regulates the lysosomal clearance of MAPT/tau JM Carosi, LK Hein, M van den Hurk, R Adams, B Milky, S Singh, C Bardy, ... Autophagy, 2020 | 36 | 2020 |
A 3-D in vitro co-culture model of mammary gland involution JJ Campbell, LA Botos, TJ Sargeant, N Davidenko, RE Cameron, ... Integrative Biology 6 (6), 618-626, 2014 | 36 | 2014 |
Stat3-mediated alterations in lysosomal membrane protein composition B Lloyd-Lewis, CC Krueger, TJ Sargeant, ME D’Angelo, MJ Deery, ... Journal of Biological Chemistry 293 (12), 4244-4261, 2018 | 31 | 2018 |
Mu opioid receptors are expressed on radial glia but not migrating neuroblasts in the late embryonic mouse brain TJ Sargeant, DJ Day, EM Mrkusich, DF Foo, JH Miller Brain research 1175, 28-38, 2007 | 30 | 2007 |
Measurement of autophagic flux in humans: an optimized method for blood samples J Bensalem, KJ Hattersley, LK Hein, XT Teong, JM Carosi, S Hassiotis, ... Autophagy, 2020 | 28 | 2020 |