| Osteoarthritis: toward a comprehensive understanding of pathological mechanism DI Chen, J Shen, W Zhao, T Wang, L Han, JL Hamilton, HJ Im Bone research 5 (1), 1-13, 2017 | 854 | 2017 |
| Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis M Wang, J Shen, H Jin, HJ Im, J Sandy, D Chen Annals of the New York Academy of Sciences 1240 (1), 61-69, 2011 | 228 | 2011 |
| TGF-β signaling and the development of osteoarthritis J Shen, S Li, D Chen Bone research 2 (1), 1-7, 2014 | 225 | 2014 |
| Inflammation and epigenetic regulation in osteoarthritis J Shen, Y Abu-Amer, RJ O’Keefe, A McAlinden Connective tissue research 58 (1), 49-63, 2017 | 190 | 2017 |
| Deletion of the transforming growth factor β receptor type II gene in articular chondrocytes leads to a progressive osteoarthritis‐like phenotype in mice J Shen, J Li, B Wang, H Jin, M Wang, Y Zhang, Y Yang, HJ Im, R O'Keefe, ... Arthritis & Rheumatism 65 (12), 3107-3119, 2013 | 168 | 2013 |
| LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis M Arra, G Swarnkar, K Ke, JE Otero, J Ying, X Duan, T Maruyama, MF Rai, ... Nature communications 11 (1), 3427, 2020 | 121 | 2020 |
| Conditional activation of β‐catenin signaling in mice leads to severe defects in intervertebral disc tissue M Wang, D Tang, B Shu, B Wang, H Jin, S Hao, KA Dresser, J Shen, ... Arthritis & Rheumatism 64 (8), 2611-2623, 2012 | 107 | 2012 |
| TGF-β signaling plays an essential role in the growth and maintenance of intervertebral disc tissue H Jin, J Shen, B Wang, M Wang, B Shu, D Chen FEBS letters 585 (8), 1209-1215, 2011 | 101 | 2011 |
| NOTCH signaling in skeletal progenitors is critical for fracture repair C Wang, JA Inzana, AJ Mirando, Y Ren, Z Liu, J Shen, RJ O’Keefe, ... The Journal of clinical investigation 126 (4), 1471-1481, 2016 | 97 | 2016 |
| Sustained oxygenation accelerates diabetic wound healing by promoting epithelialization and angiogenesis and decreasing inflammation Y Guan, H Niu, Z Liu, Y Dang, J Shen, M Zayed, L Ma, J Guan Science Advances 7 (35), eabj0153, 2021 | 92 | 2021 |
| Runx2 plays a central role in Osteoarthritis development D Chen, DJ Kim, J Shen, Z Zou, RJ O'Keefe Journal of orthopaedic translation 23, 132-139, 2020 | 54 | 2020 |
| Distribution and alteration of lymphatic vessels in knee joints of normal and osteoarthritic mice J Shi, Q Liang, M Zuscik, J Shen, D Chen, H Xu, YJ Wang, Y Chen, ... Arthritis & rheumatology 66 (3), 657-666, 2014 | 50 | 2014 |
| Distinct metabolic programs induced by TGF-β1 and BMP2 in human articular chondrocytes with osteoarthritis C Wang, RM Silverman, J Shen, RJ O'Keefe Journal of orthopaedic translation 12, 66-73, 2018 | 49 | 2018 |
| Bovine lactoferricin is anti‐inflammatory and anti‐catabolic in human articular cartilage and synovium D Yan, D Chen, J Shen, G Xiao, AJ Van Wijnen, HJ Im Journal of cellular physiology 228 (2), 447-456, 2013 | 49 | 2013 |
| DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism J Shen, C Wang, D Li, T Xu, J Myers, JM Ashton, T Wang, MJ Zuscik, ... JCI insight 2 (12), 2017 | 45 | 2017 |
| FoxO1 is a crucial mediator of TGF-β/TAK1 signaling and protects against osteoarthritis by maintaining articular cartilage homeostasis C Wang, J Shen, J Ying, D Xiao, RJ O’Keefe Proceedings of the National Academy of Sciences 117 (48), 30488-30497, 2020 | 39 | 2020 |
| Activation Of B-Catenin Signalling Leads To Temporomandibular Joint Defects M Wang, S Li, W Xie, J Shen, HJ Im, JD Holz, TGH Diekwisch, D Chen European cells & materials 28, 223, 2014 | 34 | 2014 |
| Loss of Dnmt3b in Chondrocytes Leads to Delayed Endochondral Ossification and Fracture Repair C Wang, Y Abu‐Amer, RJ O'Keefe, J Shen Journal of Bone and Mineral Research 33 (2), 283-297, 2018 | 32 | 2018 |
| CCN1 regulates chondrocyte maturation and cartilage development Y Zhang, T Sheu, D Hoak, J Shen, MJ Hilton, MJ Zuscik, JH Jonason, ... Journal of Bone and Mineral Research 31 (3), 549-559, 2016 | 29 | 2016 |
| High oxygen preservation hydrogels to augment cell survival under hypoxic condition H Niu, C Li, Y Guan, Y Dang, X Li, Z Fan, J Shen, L Ma, J Guan Acta biomaterialia 105, 56-67, 2020 | 27 | 2020 |
