Phase transitions in the assembly of multivalent signalling proteins P Li, S Banjade, HC Cheng, S Kim, B Chen, L Guo, M Llaguno, ... Nature 483 (7389), 336-340, 2012 | 1763 | 2012 |
Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation D Sun, R Wu, J Zheng, P Li, L Yu Cell research 28 (4), 405-415, 2018 | 281 | 2018 |
Histone modifications regulate chromatin compartmentalization by contributing to a phase separation mechanism L Wang, Y Gao, X Zheng, C Liu, S Dong, R Li, G Zhang, Y Wei, H Qu, Y Li, ... Molecular cell 76 (4), 646-659. e6, 2019 | 203 | 2019 |
Structural and energetic mechanisms of cooperative autoinhibition and activation of Vav1 B Yu, IRS Martins, P Li, GK Amarasinghe, J Umetani, ... Cell 140 (2), 246-256, 2010 | 164 | 2010 |
Arabidopsis FLL2 promotes liquid–liquid phase separation of polyadenylation complexes X Fang, L Wang, R Ishikawa, Y Li, M Fiedler, F Liu, G Calder, B Rowan, ... Nature 569 (7755), 265-269, 2019 | 148 | 2019 |
Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly R Zhang, BR So, P Li, J Yong, T Glisovic, L Wan, G Dreyfuss Cell 146 (3), 384-395, 2011 | 126 | 2011 |
Internal dynamics control activation and activity of the autoinhibited Vav DH domain P Li, IRS Martins, GK Amarasinghe, MK Rosen Nature structural & molecular biology 15 (6), 613-618, 2008 | 112 | 2008 |
Liquid-liquid phase separation in biology: mechanisms, physiological functions and human diseases H Zhang, X Ji, P Li, C Liu, J Lou, Z Wang, W Wen, Y Xiao, M Zhang, X Zhu Science China Life Sciences 63, 953-985, 2020 | 108 | 2020 |
Multivalent m6A motifs promote phase separation of YTHDF proteins Y Gao, G Pei, D Li, R Li, Y Shao, QC Zhang, P Li Cell research 29 (9), 767-769, 2019 | 104 | 2019 |
Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome JY Lu, L Chang, T Li, T Wang, Y Yin, G Zhan, X Han, K Zhang, Y Tao, ... Cell research 31 (6), 613-630, 2021 | 75 | 2021 |
A U1 snRNP–specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange BR So, L Wan, Z Zhang, P Li, E Babiash, J Duan, I Younis, G Dreyfuss Nature structural & molecular biology 23 (3), 225-230, 2016 | 71 | 2016 |
Plant HP1 protein ADCP1 links multivalent H3K9 methylation readout to heterochromatin formation S Zhao, L Cheng, Y Gao, B Zhang, X Zheng, L Wang, P Li, Q Sun, H Li Cell research 29 (1), 54-66, 2019 | 68 | 2019 |
Phase separation of SERRATE drives dicing body assembly and promotes miRNA processing in Arabidopsis D Xie, M Chen, J Niu, L Wang, Y Li, X Fang, P Li, Y Qi Nature Cell Biology 23 (1), 32-39, 2021 | 59 | 2021 |
Rett syndrome-causing mutations compromise MeCP2-mediated liquid–liquid phase separation of chromatin L Wang, M Hu, MQ Zuo, J Zhao, D Wu, L Huang, Y Wen, Y Li, P Chen, ... Cell research 30 (5), 393-407, 2020 | 57 | 2020 |
Mitotic implantation of the transcription factor prospero via phase separation drives terminal neuronal differentiation X Liu, J Shen, L Xie, Z Wei, C Wong, Y Li, X Zheng, P Li, Y Song Developmental Cell 52 (3), 277-293. e8, 2020 | 53 | 2020 |
ROS regulated reversible protein phase separation synchronizes plant flowering X Huang, S Chen, W Li, L Tang, Y Zhang, N Yang, Y Zou, X Zhai, N Xiao, ... Nature Chemical Biology 17 (5), 549-557, 2021 | 47 | 2021 |
Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein α-subunit CJ Thomas, X Du, PL Li, Y Wang, EM Ross, SR Sprang Proceedings of the National Academy of Sciences 101 (20), 7560-7565, 2004 | 44 | 2004 |
Loci-specific phase separation of FET fusion oncoproteins promotes gene transcription L Zuo, G Zhang, M Massett, J Cheng, Z Guo, L Wang, Y Gao, R Li, ... Nature communications 12 (1), 1491, 2021 | 40 | 2021 |
Phase separation in regulation of aggrephagy D Sun, R Wu, P Li, L Yu Journal of molecular biology 432 (1), 160-169, 2020 | 37 | 2020 |
CCT2 is an aggrephagy receptor for clearance of solid protein aggregates X Ma, C Lu, Y Chen, S Li, N Ma, X Tao, Y Li, J Wang, M Zhou, YB Yan, ... Cell 185 (8), 1325-1345. e22, 2022 | 31 | 2022 |