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Jan Burian
Jan Burian
Postdoctoral Associate, Rockefeller University
在 rockefeller.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The mycobacterial transcriptional regulator whiB7 gene links redox homeostasis and intrinsic antibiotic resistance
J Burian, S Ramón-García, G Sweet, A Gómez-Velasco, Y Av-Gay, ...
Journal of Biological Chemistry 287 (1), 299-310, 2012
1622012
The mycobacterial antibiotic resistance determinant WhiB7 acts as a transcriptional activator by binding the primary sigma factor SigA (RpoV)
J Burian, G Yim, M Hsing, P Axerio-Cilies, A Cherkasov, GB Spiegelman, ...
Nucleic acids research 41 (22), 10062-10076, 2013
1142013
A system for the targeted amplification of bacterial gene clusters multiplies antibiotic yield in Streptomyces coelicolor
T Murakami, J Burian, K Yanai, MJ Bibb, CJ Thompson
Proceedings of the National Academy of Sciences 108 (38), 16020-16025, 2011
892011
WhiB7, a transcriptional activator that coordinates physiology with intrinsic drug resistance in Mycobacterium tuberculosis
J Burian, S Ramon-Garcia, CG Howes, CJ Thompson
Expert review of anti-infective therapy 10 (9), 1037-1047, 2012
742012
WhiB7, an Fe-S-dependent transcription factor that activates species-specific repertoires of drug resistance determinants in actinobacteria
S Ramón-García, C Ng, PR Jensen, M Dosanjh, J Burian, RP Morris, ...
Journal of Biological Chemistry 288 (48), 34514-34528, 2013
692013
Antagonism between Front-Line Antibiotics Clarithromycin and Amikacin in the Treatment of Mycobacterium abscessus Infections Is Mediated by the whiB7 Gene
M Pryjma, J Burian, K Kuchinski, CJ Thompson
Antimicrobial agents and chemotherapy 61 (11), 10.1128/aac. 01353-17, 2017
672017
Rifabutin acts in synergy and is bactericidal with frontline Mycobacterium abscessus antibiotics clarithromycin and tigecycline, suggesting a potent treatment combination
M Pryjma, J Burian, CJ Thompson
Antimicrobial agents and chemotherapy 62 (8), 10.1128/aac. 00283-18, 2018
512018
Regulatory genes coordinating antibiotic‐induced changes in promoter activity and early transcriptional termination of the mycobacterial intrinsic resistance gene whiB7
J Burian, CJ Thompson
Molecular microbiology 107 (3), 402-415, 2018
302018
Multiplexed mobilization and expression of biosynthetic gene clusters
V Libis, LW MacIntyre, R Mehmood, L Guerrero, MA Ternei, N Antonovsky, ...
Nature Communications 13 (1), 5256, 2022
182022
High-throughput retrieval of target sequences from complex clone libraries using CRISPRi
J Burian, VK Libis, YA Hernandez, L Guerrero-Porras, MA Ternei, ...
Nature biotechnology 41 (5), 626-630, 2023
112023
Present and future outlooks on environmental DNA-based methods for antibiotic discovery
AF Rosenzweig, J Burian, SF Brady
Current opinion in microbiology 75, 102335, 2023
72023
DNA glycosylases provide antiviral defence in prokaryotes
AA Hossain, YZ Pigli, CF Baca, S Heissel, A Thomas, VK Libis, J Burian, ...
Nature, 1-7, 2024
42024
Research briefing
J Burian, SF Brady
Nature Biotechnology 41, 620-621, 2023
2023
6.02 General Strategies for Biosynthetic Gene Cluster Identification, Capture, and Heterologous Expression
J Burian, SF Brady
Comprehensive Natural Products III: Chemistry and Biology, 3, 2020
2020
Characterization of the transcriptional regulator WhiB7 establishes a link between metabolism and intrinsic antibiotic resistance in mycobacteria
J Burian
University of British Columbia, 2015
2015
Insights into whiB7 activation and action
J Burian, S Ramón-García, G Sweet, A Gómez-Velasco, Y Av-Gay, ...
2011
Lamichhane G Liu J Machado D Martins M
H Morbidoni, H Boshoff, P Brennan, J Burian, R Buxton, K Chater, ...
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