Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma RE Davis, VN Ngo, G Lenz, P Tolar, RM Young, PB Romesser, ... Nature 463 (7277), 88-92, 2010 | 1902 | 2010 |
Genetics and pathogenesis of diffuse large B-cell lymphoma R Schmitz, GW Wright, DW Huang, CA Johnson, JD Phelan, JQ Wang, ... New England journal of medicine 378 (15), 1396-1407, 2018 | 1838 | 2018 |
Oncogenically active MYD88 mutations in human lymphoma VN Ngo, RM Young, R Schmitz, S Jhavar, W Xiao, KH Lim, ... Nature 470 (7332), 115-119, 2011 | 1738 | 2011 |
Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program AL Shaffer, KI Lin, TC Kuo, X Yu, EM Hurt, A Rosenwald, JM Giltnane, ... Immunity 17 (1), 51-62, 2002 | 1309 | 2002 |
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation AL Shaffer, M Shapiro-Shelef, NN Iwakoshi, AH Lee, SB Qian, H Zhao, ... Immunity 21 (1), 81-93, 2004 | 1207 | 2004 |
Control of inflammation, cytokine expression, and germinal center formation by BCL-6 AL Dent, AL Shaffer, X Yu, D Allman, LM Staudt Science 276 (5312), 589-592, 1997 | 1197 | 1997 |
Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma WH Wilson, RM Young, R Schmitz, Y Yang, S Pittaluga, G Wright, CJ Lih, ... Nature medicine 21 (8), 922-926, 2015 | 1187 | 2015 |
Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways G Lenz, GW Wright, NCT Emre, H Kohlhammer, SS Dave, RE Davis, ... Proceedings of the National Academy of Sciences 105 (36), 13520-13525, 2008 | 1164 | 2008 |
BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control AL Shaffer, X Yu, Y He, J Boldrick, EP Chan, LM Staudt Immunity 13 (2), 199-212, 2000 | 1095 | 2000 |
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics R Schmitz, RM Young, M Ceribelli, S Jhavar, W Xiao, M Zhang, G Wright, ... Nature 490 (7418), 116-120, 2012 | 981 | 2012 |
IRF4 addiction in multiple myeloma AL Shaffer, NCT Emre, L Lamy, VN Ngo, G Wright, W Xiao, J Powell, ... Nature 454 (7201), 226-231, 2008 | 762 | 2008 |
Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation R Sciammas, AL Shaffer, JH Schatz, H Zhao, LM Staudt, H Singh Immunity 25 (2), 225-236, 2006 | 676 | 2006 |
Lymphoid malignancies: the dark side of B-cell differentiation AL Shaffer, A Rosenwald, LM Staudt Nature Reviews Immunology 2 (12), 920-933, 2002 | 608 | 2002 |
Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma Y Yang, AL Shaffer, NCT Emre, M Ceribelli, M Zhang, G Wright, W Xiao, ... Cancer cell 21 (6), 723-737, 2012 | 592 | 2012 |
Pathogenesis of human B cell lymphomas AL Shaffer III, RM Young, LM Staudt Annual review of immunology 30, 565-610, 2012 | 538 | 2012 |
Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma EM Hurt, A Wiestner, A Rosenwald, AL Shaffer, E Campo, T Grogan, ... Cancer cell 5 (2), 191-199, 2004 | 490 | 2004 |
Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation C Tunyaplin, AL Shaffer, CD Angelin-Duclos, X Yu, LM Staudt, KL Calame The Journal of Immunology 173 (2), 1158-1165, 2004 | 474 | 2004 |
Signatures of the immune response AL Shaffer, A Rosenwald, EM Hurt, JM Giltnane, LT Lam, OK Pickeral, ... Immunity 15 (3), 375-385, 2001 | 403 | 2001 |
Cell type–specific chromatin structure determines the targeting of V (D) J recombinase activity in vitro P Stanhope-Baker, KM Hudson, AL Shaffer, A Constantinescu, ... Cell 85 (6), 887-897, 1996 | 373 | 1996 |
A multiprotein supercomplex controlling oncogenic signalling in lymphoma JD Phelan, RM Young, DE Webster, S Roulland, GW Wright, M Kasbekar, ... Nature 560 (7718), 387-391, 2018 | 351 | 2018 |