A fluorophore ligase for site-specific protein labeling inside living cells C Uttamapinant, KA White, H Baruah, S Thompson, M Fernández-Suárez, ... Proceedings of the National Academy of Sciences 107 (24), 10914-10919, 2010 | 352 | 2010 |
Cancer cell behaviors mediated by dysregulated pH dynamics at a glance KA White, BK Grillo-Hill, DL Barber Journal of cell science 130 (4), 663-669, 2017 | 320 | 2017 |
Yeast display evolution of a kinetically efficient 13-amino acid substrate for lipoic acid ligase S Puthenveetil, DS Liu, KA White, S Thompson, AY Ting Journal of the American Chemical Society 131 (45), 16430-16438, 2009 | 123 | 2009 |
Site-specific protein labeling using PRIME and chelation-assisted click chemistry C Uttamapinant, MI Sanchez, DS Liu, JZ Yao, KA White, S Grecian, ... Nature protocols 8 (8), 1620-1634, 2013 | 106 | 2013 |
Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins KA White, DG Ruiz, ZA Szpiech, NB Strauli, RD Hernandez, MP Jacobson, ... Science signaling 10 (495), eaam9931, 2017 | 84 | 2017 |
Imaging trans-cellular neurexin-neuroligin interactions by enzymatic probe ligation DS Liu, KH Loh, SS Lam, KA White, AY Ting PloS one 8 (2), e52823, 2013 | 56 | 2013 |
β-Catenin is a pH sensor with decreased stability at higher intracellular pH KA White, BK Grillo-Hill, M Esquivel, J Peralta, VN Bui, I Chire, DL Barber Journal of Cell Biology 217 (11), 3965-3976, 2018 | 47 | 2018 |
A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1 Y Vercoulen, Y Kondo, JS Iwig, AB Janssen, KA White, M Amini, ... Elife 6, e29002, 2017 | 47 | 2017 |
Prominent Features Of The Amino Acid Mutation Landscape In Cancer ZA Szpiech, NB Strauli, KA White, DG Ruiz, MP Jacobson, DL Barber, ... PLOS ONE 12 (8), e0183273, 2017 | 47 | 2017 |
Intracellular pH regulates cancer and stem cell behaviors: a protein dynamics perspective Y Liu, KA White, DL Barber Frontiers in Oncology 10, 1401, 2020 | 38 | 2020 |
A histidine cluster in the cytoplasmic domain of the Na-H exchanger NHE1 confers pH-sensitive phospholipid binding and regulates transporter activity BA Webb, KA White, BK Grillo-Hill, A Schönichen, C Choi, DL Barber Journal of Biological Chemistry 291 (46), 24096-24104, 2016 | 38 | 2016 |
Cancer and pH dynamics: Transcriptional regulation, proteostasis, and the need for new molecular tools BJ Czowski, R Romero-Moreno, KJ Trull, KA White Cancers 12 (10), 2760, 2020 | 26 | 2020 |
An optogenetic tool to raise intracellular pH in single cells and drive localized membrane dynamics CET Donahue, MD Siroky, KA White Journal of the American Chemical Society 143 (45), 18877-18887, 2021 | 24 | 2021 |
Intracellular pH dynamics and charge-changing somatic mutations in cancer KA White, K Kisor, DL Barber Cancer and Metastasis Reviews 38, 17-24, 2019 | 23 | 2019 |
Single-cell intracellular pH dynamics regulate the cell cycle by timing the G1 exit and G2 transition JS Spear, KA White Journal of Cell Science 136 (10), jcs260458, 2023 | 16 | 2023 |
Directed Evolution of a Probe Ligase with Activity in the Secretory Pathway and Application to Imaging Intercellular Protein–Protein Interactions KA White, PM Zegelbone Biochemistry 52 (21), 3728-3739, 2013 | 12 | 2013 |
An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity SCD Luna LA, Lesecq Z, White KA, Hoang A, Scott DA, Zagnitko O, Bobkov AA ... Biochem J. 477 (16), 2999, 2020 | 10 | 2020 |
Low pH facilitates heterodimerization of mutant isocitrate dehydrogenase IDH1-R132H and promotes production of 2-hydroxyglutarate R Sesanto, JF Kuehn, DL Barber, KA White Biochemistry 60 (25), 1983-1994, 2021 | 6 | 2021 |
SGLT2-independent effects of canagliflozin on NHE3 and mitochondrial complex I activity inhibit proximal tubule fluid transport and albumin uptake WN Albalawy, EB Youm, KE Shipman, KJ Trull, CJ Baty, KR Long, ... American Journal of Physiology-Renal Physiology, 2024 | 3 | 2024 |
Charting a new frontier integrating mathematical modeling in complex biological systems from molecules to ecosystems KA White, KD McEntire, NR Buan, L Robinson, E Barbar Integrative and comparative biology 61 (6), 2255-2266, 2021 | 3 | 2021 |