Control of multidrug resistance gene mdr1 and cancer resistance to chemotherapy by the longevity gene sirt1 F Chu, PM Chou, X Zheng, BL Mirkin, A Rebbaa Cancer research 65 (22), 10183-10187, 2005 | 210 | 2005 |
Siva-1 binds to and inhibits BCL-XL-mediated protection against UV radiation-induced apoptosis L Xue, F Chu, Y Cheng, X Sun, A Borthakur, M Ramarao, P Pandey, M Wu, ... Proceedings of the National Academy of Sciences 99 (10), 6925-6930, 2002 | 114 | 2002 |
Identification of midkine as a mediator for intercellular transfer of drug resistance BL Mirkin, S Clark, X Zheng, F Chu, BD White, M Greene, A Rebbaa Oncogene 24 (31), 4965-4974, 2005 | 96 | 2005 |
Novel function of the thyroid hormone analog tetraiodothyroacetic acid: a cancer chemosensitizing and anti-cancer agent A Rebbaa, F Chu, FB Davis, PJ Davis, SA Mousa Angiogenesis 11, 269-276, 2008 | 77 | 2008 |
The role of histone acetylation versus DNA damage in drug-induced senescence and apoptosis A Rebbaa, X Zheng, F Chu, BL Mirkin Cell Death & Differentiation 13 (11), 1960-1967, 2006 | 70 | 2006 |
The Siva-1 putative amphipathic helical region (SAH) is sufficient to bind to BCL-XL and sensitize cells to UV radiation induced apoptosis F Chu, A Borthakur, X Sun, J Barkinge, R Gudi, S Hawkins, KVS Prasad Apoptosis 9, 83-95, 2004 | 70 | 2004 |
Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism X Zheng, F Chu, PM Chou, C Gallati, U Dier, BL Mirkin, SA Mousa, ... American Journal of Physiology-Cell Physiology 296 (1), C65-C74, 2009 | 63 | 2009 |
Role of the proteolytic hierarchy between cathepsin L, cathepsin D and caspase-3 in regulation of cellular susceptibility to apoptosis and autophagy X Zheng, F Chu, BL Mirkin, T Sudha, SA Mousa, A Rebbaa Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (12), 2294-2300, 2008 | 61 | 2008 |
Siva-1 negatively regulates NF-κB activity: effect on T-cell receptor-mediated activation-induced cell death (AICD) R Gudi, J Barkinge, S Hawkins, F Chu, S Manicassamy, Z Sun, ... Oncogene 25 (24), 3458-3462, 2006 | 57 | 2006 |
Differential effect of long-term drug selection with doxorubicin and vorinostat on neuroblastoma cells with cancer stem cell characteristics X Zheng, J Naiditch, M Czurylo, C Jie, T Lautz, S Clark, N Jafari, Y Qiu, ... Cell death & disease 4 (7), e740-e740, 2013 | 43 | 2013 |
Expression of Siva-1 protein or its putative amphipathic helical region enhances cisplatin-induced apoptosis in breast cancer cells: effect of elevated levels of BCL-2 F Chu, J Barkinge, S Hawkins, R Gudi, R Salgia, PVS Kanteti Cancer research 65 (12), 5301-5309, 2005 | 43 | 2005 |
Glycolysis inhibition and its effect in doxorubicin resistance in neuroblastoma JF Bean, YY Qiu, S Yu, S Clark, F Chu, MB Madonna Journal of pediatric surgery 49 (6), 981-984, 2014 | 37 | 2014 |
The anti-angiogenic activity of NSITC, a specific cathepsin L inhibitor A Rebbaa, F Chu, T Sudha, C Gallati, U Dier, E Dyskin, M Yalcin, ... Anticancer research 29 (11), 4473-4481, 2009 | 37 | 2009 |
The p53-induced Siva-1 plays a significant role in cisplatin-mediated apoptosis JL Barkinge, R Gudi, H Sarah, F Chu, A Borthakur, BS Prabhakar, ... Journal of carcinogenesis 8, 2009 | 27 | 2009 |
Mesenchymal change and drug resistance in neuroblastoma JA Naiditch, C Jie, TB Lautz, S Yu, S Clark, D Voronov, F Chu, ... Journal of Surgical Research 193 (1), 279-288, 2015 | 22 | 2015 |
The effect of vorinostat on the development of resistance to doxorubicin in neuroblastoma TB Lautz, C Jie, S Clark, JA Naiditch, N Jafari, YY Qiu, X Zheng, F Chu, ... PLoS One 7 (7), e40816, 2012 | 21 | 2012 |
Efficacy of class I and II vs class III histone deacetylase inhibitors in neuroblastoma TB Lautz, JA Naiditch, S Clark, F Chu, MB Madonna Journal of pediatric surgery 47 (6), 1267-1271, 2012 | 16 | 2012 |
Cellular conditioning with trichostatin A enhances the anti‐stress response through up‐regulation of HDAC4 and down‐regulation of the IGF/Akt pathway F Chu, P Chou, BL Mirkin, SA Mousa, A Rebbaa Aging Cell 7 (4), 516-525, 2008 | 15 | 2008 |
Midkine Mediates Intercellular Crosstalk between Drug‐Resistant and Drug‐Sensitive Neuroblastoma Cells In Vitro and In Vivo F Chu, JA Naiditch, S Clark, YY Qiu, X Zheng, TB Lautz, JL Holub, ... International Scholarly Research Notices 2013 (1), 518637, 2013 | 9 | 2013 |
The role of nerve growth factor in caspase-dependent apoptosis in human BE (2) C neuroblastoma JL Holub, YY Qiu, F Chu, MB Madonna Journal of Pediatric Surgery 46 (6), 1191-1196, 2011 | 9 | 2011 |