| Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ... Science 352 (6282), 189-196, 2016 | 3933 | 2016 |
| Fatal toxic effects associated with immune checkpoint inhibitors: a systematic review and meta-analysis DY Wang, JE Salem, JV Cohen, S Chandra, C Menzer, F Ye, S Zhao, ... JAMA oncology 4 (12), 1721-1728, 2018 | 2022 | 2018 |
| Defining T cell states associated with response to checkpoint immunotherapy in melanoma M Sade-Feldman, K Yizhak, SL Bjorgaard, JP Ray, CG de Boer, ... Cell 175 (4), 998-1013. e20, 2018 | 1411 | 2018 |
| Myocarditis in patients treated with immune checkpoint inhibitors SS Mahmood, MG Fradley, JV Cohen, A Nohria, KL Reynolds, ... Journal of the American College of Cardiology 71 (16), 1755-1764, 2018 | 1242 | 2018 |
| EGFR mutations and ALK rearrangements are associated with low response rates to PD-1 pathway blockade in non–small cell lung cancer: a retrospective analysis JF Gainor, AT Shaw, LV Sequist, X Fu, CG Azzoli, Z Piotrowska, ... Clinical cancer research 22 (18), 4585-4593, 2016 | 1122 | 2016 |
| A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ... Cell 175 (4), 984-997. e24, 2018 | 1046 | 2018 |
| BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma DT Frederick, A Piris, AP Cogdill, ZA Cooper, C Lezcano, CR Ferrone, ... Clinical cancer research 19 (5), 1225-1231, 2013 | 996 | 2013 |
| Resistance to checkpoint blockade therapy through inactivation of antigen presentation M Sade-Feldman, YJ Jiao, JH Chen, MS Rooney, M Barzily-Rokni, ... Nature communications 8 (1), 1136, 2017 | 823 | 2017 |
| Anti-PD-1 therapy in patients with advanced melanoma and preexisting autoimmune disorders or major toxicity with ipilimumab AM Menzies, DB Johnson, S Ramanujam, VG Atkinson, ANM Wong, ... Annals of Oncology 28 (2), 368-376, 2017 | 809 | 2017 |
| Ipilimumab therapy in patients with advanced melanoma and preexisting autoimmune disorders DB Johnson, RJ Sullivan, PA Ott, MS Carlino, NI Khushalani, F Ye, ... JAMA oncology 2 (2), 234-240, 2016 | 628 | 2016 |
| Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma N Auslander, G Zhang, JS Lee, DT Frederick, B Miao, T Moll, T Tian, ... Nature medicine 24 (10), 1545-1549, 2018 | 587 | 2018 |
| Overall survival benefit with tebentafusp in metastatic uveal melanoma P Nathan, JC Hassel, P Rutkowski, JF Baurain, MO Butler, M Schlaak, ... New England Journal of Medicine 385 (13), 1196-1206, 2021 | 549 | 2021 |
| MAP Kinase Pathway Alterations in BRAF-Mutant Melanoma Patients with Acquired Resistance to Combined RAF/MEK Inhibition N Wagle, EM Van Allen, DJ Treacy, DT Frederick, ZA Cooper, ... Cancer discovery 4 (1), 61-68, 2014 | 529 | 2014 |
| Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy DB Johnson, MV Estrada, R Salgado, V Sanchez, DB Doxie, SR Opalenik, ... Nature communications 7 (1), 10582, 2016 | 528 | 2016 |
| Clusters of circulating tumor cells traverse capillary-sized vessels SH Au, BD Storey, JC Moore, Q Tang, YL Chen, S Javaid, AF Sarioglu, ... Proceedings of the National Academy of Sciences 113 (18), 4947-4952, 2016 | 474 | 2016 |
| Targeted next generation sequencing identifies markers of response to PD-1 blockade DB Johnson, GM Frampton, MJ Rioth, E Yusko, Y Xu, X Guo, RC Ennis, ... Cancer immunology research 4 (11), 959-967, 2016 | 472 | 2016 |
| Ipilimumab-induced hypophysitis: a detailed longitudinal analysis in a large cohort of patients with metastatic melanoma AT Faje, R Sullivan, D Lawrence, NA Tritos, R Fadden, A Klibanski, ... The Journal of Clinical Endocrinology & Metabolism 99 (11), 4078-4085, 2014 | 464 | 2014 |
| Resistance to BRAF-targeted therapy in melanoma RJ Sullivan, KT Flaherty European journal of cancer 49 (6), 1297-1304, 2013 | 424 | 2013 |
| High‐dose glucocorticoids for the treatment of ipilimumab‐induced hypophysitis is associated with reduced survival in patients with melanoma AT Faje, D Lawrence, K Flaherty, C Freedman, R Fadden, K Rubin, ... Cancer 124 (18), 3706-3714, 2018 | 403 | 2018 |
| The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 393 | 2020 |
