Closely related T-memory stem cells correlate with in vivo expansion of CAR. CD19-T cells and are preserved by IL-7 and IL-15 Y Xu, M Zhang, CA Ramos, A Durett, E Liu, O Dakhova, H Liu, ... Blood, The Journal of the American Society of Hematology 123 (24), 3750-3759, 2014 | 758 | 2014 |
Antitumor responses in the absence of toxicity in solid tumors by targeting B7-H3 via chimeric antigen receptor T cells H Du, K Hirabayashi, S Ahn, NP Kren, SA Montgomery, X Wang, ... Cancer cell 35 (2), 221-237. e8, 2019 | 341 | 2019 |
Interleukin-23 engineering improves CAR T cell function in solid tumors X Ma, P Shou, C Smith, Y Chen, H Du, C Sun, N Porterfield Kren, ... Nature biotechnology 38 (4), 448-459, 2020 | 174 | 2020 |
THEMIS-SHP1 recruitment by 4-1BB tunes LCK-mediated priming of chimeric antigen receptor-redirected T cells C Sun, P Shou, H Du, K Hirabayashi, Y Chen, LE Herring, S Ahn, Y Xu, ... Cancer Cell 37 (2), 216-225. e6, 2020 | 119 | 2020 |
Glycolysis determines dichotomous regulation of T cell subsets in hypoxia Y Xu, A Chaudhury, M Zhang, B Savoldo, LS Metelitsa, J Rodgers, ... The Journal of clinical investigation 126 (7), 2678-2688, 2016 | 113 | 2016 |
HERV-K–specific T cells eliminate diverse HIV-1/2 and SIV primary isolates RB Jones, KE Garrison, S Mujib, V Mihajlovic, N Aidarus, DV Hunter, ... The Journal of clinical investigation 122 (12), 2012 | 102 | 2012 |
Dual-targeting CAR-T cells with optimal co-stimulation and metabolic fitness enhance antitumor activity and prevent escape in solid tumors K Hirabayashi, H Du, Y Xu, P Shou, X Zhou, G Fucá, E Landoni, C Sun, ... Nature cancer 2 (9), 904-918, 2021 | 81 | 2021 |
LINE-1 retrotransposable element DNA accumulates in HIV-1-infected cells RB Jones, H Song, Y Xu, KE Garrison, AA Buzdin, N Anwar, DV Hunter, ... Journal of virology 87 (24), 13307-13320, 2013 | 71 | 2013 |
Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer J Zhang, G Zhang, W Zhang, L Bai, L Wang, T Li, L Yan, Y Xu, D Chen, ... Cell Death & Differentiation 29 (11), 2247-2261, 2022 | 34 | 2022 |
CAR-macrophages and CAR-T cells synergistically kill tumor cells in vitro M Liu, J Liu, Z Liang, K Dai, J Gan, Q Wang, Y Xu, YH Chen, X Wan Cells 11 (22), 3692, 2022 | 21 | 2022 |
Selection bias: maintaining less-differentiated T cells for adoptive immunotherapy Y Xu, G Dotti The Journal of clinical investigation 126 (1), 35-37, 2016 | 13 | 2016 |
Exclusive enteral nutrition exerts anti-inflammatory effects through modulating microbiota, bile acid metabolism, and immune activities F Xiao, X Gao, H Hu, J Le, Y Chen, X Shu, Z Liang, Y Xu, Y Wang, ... Nutrients 14 (21), 4463, 2022 | 8 | 2022 |
Identification of genetic modifiers enhancing B7-H3-targeting CAR T cell therapy against glioblastoma through large-scale CRISPRi screening X Li, S Sun, W Zhang, Z Liang, Y Fang, T Sun, Y Wan, X Ma, S Zhang, ... Journal of Experimental & Clinical Cancer Research 43 (1), 95, 2024 | 1 | 2024 |
Modified t cells and methods of preparing the same G Dotti, Y Xu, X Ma US Patent App. 17/762,360, 2023 | | 2023 |