Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity LE Tavernelli, MCM Motta, CS Gonçalves, MS da Silva, MC Elias, ... Scientific Reports 9 (1), 192, 2019 | 18 | 2019 |
Trypanosoma cruzi High Mobility Group B (TcHMGB) can act as an inflammatory mediator on mammalian cells P Cribb, V Perdomo, VL Alonso, R Manarin, J Barrios-Payan, ... PLoS Neglected Tropical Diseases 11 (2), e0005350, 2017 | 13 | 2017 |
Essential Bromodomain TcBDF2 as a Drug Target against Chagas Disease A Pezza, LE Tavernelli, VL Alonso, V Perdomo, R Gabarro, R Prinjha, ... ACS infectious Diseases 8 (5), 1062-1074, 2022 | 12 | 2022 |
Alpha-Tubulin Acetylation in Trypanosoma cruzi: A Dynamic Instability of Microtubules Is Required for Replication and Cell Cycle Progression VL Alonso, ME Carloni, CS Gonçalves, G Martinez Peralta, ME Chesta, ... Frontiers in Cellular and Infection Microbiology 11, 642271, 2021 | 6 | 2021 |
Aim for the readers! Bromodomains as new targets against Chagas’ disease VL Alonso, LE Tavernelli, A Pezza, P Cribb, C Ritagliati, E Serra Current Medicinal Chemistry 26 (36), 6544-6563, 2019 | 6 | 2019 |
1,3,4-oxadiazoles as inhibitors of the atypical member of the BET family bromodomain factor 3 from Trypanosoma cruzi (TcBDF3) VL Alonso, AM Escalante, E Rodríguez Araya, G Frattini, LE Tavernelli, ... Frontiers in Microbiology 15, 1465672, 2024 | 1 | 2024 |
Identification of novel bromodomain inhibitors of Trypanosoma cruzi bromodomain factor 2 (TcBDF2) using a fluorescence polarization-based high-throughput assay LE Tavernelli, VL Alonso, I Peña, E Rodríguez Araya, R Manarin, ... Antimicrobial Agents and Chemotherapy 68 (8), e00243-24, 2024 | 1 | 2024 |
A conserved metabolic signature associated with response to fast-acting anti-malarial agents NV Simwela, WA Guiguemde, J Straimer, C Regnault, BH Stokes, ... Microbiology spectrum 11 (6), e03976-22, 2023 | 1 | 2023 |
Experimental data on the binding and activity of 1, 3, 4-Oxadiazoles to Bromodomain factor 3 (TcBDF3) of Trypanosoma cruzi VL Alonso, AM Escalante, E Rodríguez Araya, G Frattini, LE Tavernelli, ... RDA UNR, 2024 | | 2024 |