Reduction-Responsive Disassemblable Core-Cross-Linked Micelles Based on Poly(ethylene glycol)-b-poly(N-2-hydroxypropyl methacrylamide)–Lipoic Acid … R Wei, L Cheng, M Zheng, R Cheng, F Meng, C Deng, Z Zhong Biomacromolecules 13 (8), 2429-2438, 2012 | 221 | 2012 |
pH-sensitive degradable chimaeric polymersomes for the intracellular release of doxorubicin hydrochloride Y Du, W Chen, M Zheng, F Meng, Z Zhong Biomaterials 33 (29), 7291-7299, 2012 | 214 | 2012 |
Challenges in DNA delivery and recent advances in multifunctional polymeric DNA delivery systems B Shi, M Zheng, W Tao, R Chung, D Jin, D Ghaffari, OC Farokhzad Biomacromolecules 18 (8), 2231-2246, 2017 | 197 | 2017 |
Effective and targeted human orthotopic glioblastoma xenograft therapy via a multifunctional biomimetic nanomedicine Y Zou, Y Liu, Z Yang, D Zhang, Y Lu, M Zheng, X Xue, J Geng, R Chung, ... Advanced Materials 30 (51), 1803717, 2018 | 178 | 2018 |
ROS‐responsive polymeric siRNA nanomedicine stabilized by triple interactions for the robust glioblastoma combinational RNAi therapy M Zheng, Y Liu, Y Wang, D Zhang, Y Zou, W Ruan, J Yin, W Tao, JB Park, ... Advanced Materials 31 (37), 1903277, 2019 | 177 | 2019 |
Blood-brain barrier–penetrating siRNA nanomedicine for Alzheimer’s disease therapy Y Zhou, F Zhu, Y Liu, M Zheng, Y Wang, D Zhang, Y Anraku, Y Zou, J Li, ... Science advances 6 (41), eabc7031, 2020 | 162 | 2020 |
Nanotechnology-based strategies for siRNA brain delivery for disease therapy M Zheng, W Tao, Y Zou, OC Farokhzad, B Shi Trends in biotechnology 36 (5), 562-575, 2018 | 161 | 2018 |
Precise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticles HJ Kim, H Takemoto, Y Yi, M Zheng, Y Maeda, H Chaya, K Hayashi, P Mi, ... ACS nano 8 (9), 8979-8991, 2014 | 137 | 2014 |
Virus‐mimicking chimaeric polymersomes boost targeted cancer siRNA therapy in vivo Y Zou, M Zheng, W Yang, F Meng, K Miyata, HJ Kim, K Kataoka, Z Zhong Advanced Materials 29 (42), 1703285, 2017 | 134 | 2017 |
In situ forming reduction-sensitive degradable nanogels for facile loading and triggered intracellular release of proteins W Chen, M Zheng, F Meng, R Cheng, C Deng, J Feijen, Z Zhong Biomacromolecules 14 (4), 1214-1222, 2013 | 131 | 2013 |
Charge conversional biomimetic nanocomplexes as a multifunctional platform for boosting orthotopic glioblastoma RNAi therapy Y Liu, Y Zou, C Feng, A Lee, J Yin, R Chung, JB Park, H Rizos, W Tao, ... Nano letters 20 (3), 1637-1646, 2020 | 124 | 2020 |
Single siRNA nanocapsules for effective siRNA brain delivery and glioblastoma treatment Y Zou, X Sun, Y Wang, C Yan, Y Liu, J Li, D Zhang, M Zheng, RS Chung, ... Advanced Materials 32 (24), 2000416, 2020 | 120 | 2020 |
Lipoic Acid Modified Low Molecular Weight Polyethylenimine Mediates Nontoxic and Highly Potent in Vitro Gene Transfection M Zheng, Y Zhong, F Meng, R Peng, Z Zhong Molecular pharmaceutics 8 (6), 2434-2443, 2011 | 106 | 2011 |
Branched polyethylenimine derivatives with reductively cleavable periphery for safe and efficient in vitro gene transfer Y Wang, M Zheng, F Meng, J Zhang, R Peng, Z Zhong Biomacromolecules 12 (4), 1032-1040, 2011 | 105 | 2011 |
Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles Y Yi, HJ Kim, P Mi, M Zheng, H Takemoto, K Toh, BS Kim, K Hayashi, ... Journal of controlled release 244, 247-256, 2016 | 99 | 2016 |
Blood-brain barrier–penetrating single CRISPR-Cas9 nanocapsules for effective and safe glioblastoma gene therapy Y Zou, X Sun, Q Yang, M Zheng, O Shimoni, W Ruan, Y Wang, D Zhang, ... Science advances 8 (16), eabm8011, 2022 | 96 | 2022 |
Development of novel therapeutics targeting the blood–brain barrier: from barrier to carrier J Li, M Zheng, O Shimoni, WA Banks, AI Bush, JR Gamble, B Shi Advanced Science 8 (16), 2101090, 2021 | 95 | 2021 |
Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells Y Yi, HJ Kim, M Zheng, P Mi, M Naito, BS Kim, HS Min, K Hayashi, ... Journal of controlled release 295, 268-277, 2019 | 93 | 2019 |
Reversibly shielded DNA polyplexes based on bioreducible PDMAEMA-SS-PEG-SS-PDMAEMA triblock copolymers mediate markedly enhanced nonviral gene transfection C Zhu, M Zheng, F Meng, FM Mickler, N Ruthardt, X Zhu, Z Zhong Biomacromolecules 13 (3), 769-778, 2012 | 91 | 2012 |
siRNA delivery from triblock copolymer micelles with spatially-ordered compartments of PEG shell, siRNA-loaded intermediate layer, and hydrophobic core HJ Kim, K Miyata, T Nomoto, M Zheng, A Kim, X Liu, H Cabral, RJ Christie, ... Biomaterials 35 (15), 4548-4556, 2014 | 89 | 2014 |