Directing stem cell fate on hydrogel substrates by controlling cell geometry, matrix mechanics and adhesion ligand composition J Lee, AA Abdeen, D Zhang, KA Kilian Biomaterials 34 (33), 8140-8148, 2013 | 306 | 2013 |
A biodegradable nanocapsule delivers a Cas9 ribonucleoprotein complex for in vivo genome editing G Chen, AA Abdeen, Y Wang, PK Shahi, S Robertson, R Xie, M Suzuki, ... Nature nanotechnology 14 (10), 974-980, 2019 | 299 | 2019 |
Interfacial geometry dictates cancer cell tumorigenicity J Lee, AA Abdeen, KL Wycislo, TM Fan, KA Kilian Nature materials 15 (8), 856-862, 2016 | 201 | 2016 |
Anti-inflammatory ω-3 endocannabinoid epoxides DR McDougle, JE Watson, AA Abdeen, R Adili, MP Caputo, JE Krapf, ... Proceedings of the National Academy of Sciences 114 (30), E6034-E6043, 2017 | 184 | 2017 |
Rewiring mesenchymal stem cell lineage specification by switching the biophysical microenvironment J Lee, AA Abdeen, KA Kilian Scientific reports 4 (1), 5188, 2014 | 164 | 2014 |
Assembly of CRISPR ribonucleoproteins with biotinylated oligonucleotides via an RNA aptamer for precise gene editing J Carlson-Stevermer, AA Abdeen, L Kohlenberg, M Goedland, K Molugu, ... Nature communications 8 (1), 1711, 2017 | 159 | 2017 |
Matrix composition and mechanics direct proangiogenic signaling from mesenchymal stem cells AA Abdeen, JB Weiss, J Lee, KA Kilian Tissue Engineering Part A 20 (19-20), 2737-2745, 2014 | 136 | 2014 |
Controlling cell geometry on substrates of variable stiffness can tune the degree of osteogenesis in human mesenchymal stem cells J Lee, AA Abdeen, TH Huang, KA Kilian Journal of the mechanical behavior of biomedical materials 38, 209-218, 2014 | 101 | 2014 |
Temporal modulation of stem cell activity using magnetoactive hydrogels AA Abdeen, J Lee, NA Bharadwaj, RH Ewoldt, KA Kilian Advanced healthcare materials 5 (19), 2536-2544, 2016 | 90 | 2016 |
Geometric guidance of integrin mediated traction stress during stem cell differentiation J Lee, AA Abdeen, X Tang, TA Saif, KA Kilian Biomaterials 69, 174-183, 2015 | 84 | 2015 |
Versatile redox-responsive polyplexes for the delivery of plasmid DNA, messenger RNA, and CRISPR-Cas9 genome-editing machinery Y Wang, B Ma, AA Abdeen, G Chen, R Xie, K Saha, S Gong ACS applied materials & interfaces 10 (38), 31915-31927, 2018 | 71 | 2018 |
A pH-responsive silica–metal–organic framework hybrid nanoparticle for the delivery of hydrophilic drugs, nucleic acids, and CRISPR-Cas9 genome-editing machineries Y Wang, PK Shahi, R Xie, H Zhang, AA Abdeen, N Yodsanit, Z Ma, ... Journal of Controlled Release 324, 194-203, 2020 | 68 | 2020 |
Matrix directed adipogenesis and neurogenesis of mesenchymal stem cells derived from adipose tissue and bone marrow J Lee, AA Abdeen, X Tang, TA Saif, KA Kilian Acta biomaterialia 42, 46-55, 2016 | 68 | 2016 |
Influence of biophysical parameters on maintaining the mesenchymal stem cell phenotype J Lee, AA Abdeen, AS Kim, KA Kilian ACS Biomaterials Science & Engineering 1 (4), 218-226, 2015 | 50 | 2015 |
Combinatorial screening of biochemical and physical signals for phenotypic regulation of stem cell–based cartilage tissue engineering J Lee, O Jeon, M Kong, AA Abdeen, JY Shin, HN Lee, YB Lee, W Sun, ... Science advances 6 (21), eaaz5913, 2020 | 47 | 2020 |
Human iPSC modeling reveals mutation-specific responses to gene therapy in a genotypically diverse dominant maculopathy D Sinha, B Steyer, PK Shahi, KP Mueller, R Valiauga, KL Edwards, ... The American Journal of Human Genetics 107 (2), 278-292, 2020 | 45 | 2020 |
Manufacturing cell therapies using engineered biomaterials AA Abdeen, K Saha Trends in biotechnology 35 (10), 971-982, 2017 | 42 | 2017 |
Mechanochemical functionalization of disulfide linked hydrogels J Lee, MN Silberstein, AA Abdeen, SY Kim, KA Kilian Materials horizons 3 (5), 447-451, 2016 | 42 | 2016 |
Capturing extracellular matrix properties in vitro: Microengineering materials to decipher cell and tissue level processes AA Abdeen, J Lee, KA Kilian Experimental Biology and Medicine 241 (9), 930-938, 2016 | 31 | 2016 |
Melanoma topology reveals a stem-like phenotype that promotes angiogenesis J Lee, AA Abdeen, J Hedhli, KL Wycislo, IT Dobrucki, TM Fan, ... Science advances 3 (10), e1701350, 2017 | 30 | 2017 |