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Gasdermin D pore structure reveals preferential release of mature interleukin-1 S Xia, Z Zhang, VG Magupalli, JL Pablo, Y Dong, SM Vora, L Wang, ... Nature 593 (7860), 607-611, 2021 | 400 | 2021 |
LIN28 regulates stem cell metabolism and conversion to primed pluripotency J Zhang, S Ratanasirintrawoot, S Chandrasekaran, Z Wu, SB Ficarro, ... Cell stem cell 19 (1), 66-80, 2016 | 368 | 2016 |
Structural insights into energy regulation of light-harvesting complex CP29 from spinach X Pan, M Li, T Wan, L Wang, C Jia, Z Hou, X Zhao, J Zhang, W Chang Nature structural & molecular biology 18 (3), 309-315, 2011 | 328 | 2011 |
Structures and gating mechanism of human TRPM2 L Wang, TM Fu, Y Zhou, S Xia, A Greka, H Wu Science 362 (6421), eaav4809, 2018 | 150 | 2018 |
Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold P Fontana, Y Dong, X Pi, AB Tong, CW Hecksel, L Wang, TM Fu, ... Science 376 (6598), eabm9326, 2022 | 114 | 2022 |
METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing H Chen, L Gu, EA Orellana, Y Wang, J Guo, QI Liu, L Wang, Z Shen, H Wu, ... Cell research 30 (6), 544-547, 2020 | 111 | 2020 |
A biogenesis step upstream of microprocessor controls miR-17∼ 92 expression P Du, L Wang, P Sliz, RI Gregory Cell 162 (4), 885-899, 2015 | 109 | 2015 |
Structures of a complete human V-ATPase reveal mechanisms of its assembly L Wang, D Wu, CV Robinson, H Wu, TM Fu Molecular cell 80 (3), 501-511. e3, 2020 | 108 | 2020 |
Small-molecule inhibitors disrupt let-7 oligouridylation and release the selective blockade of let-7 processing by LIN28 L Wang, RG Rowe, A Jaimes, C Yu, Y Nam, DS Pearson, J Zhang, X Xie, ... Cell reports 23 (10), 3091-3101, 2018 | 107 | 2018 |
Targeting stem-loop 1 of the SARS-CoV-2 5′ UTR to suppress viral translation and Nsp1 evasion SM Vora, P Fontana, T Mao, V Leger, Y Zhang, TM Fu, J Lieberman, ... Proceedings of the National Academy of Sciences 119 (9), e2117198119, 2022 | 77 | 2022 |
LIN28 zinc knuckle domain is required and sufficient to induce let-7 oligouridylation L Wang, Y Nam, AK Lee, C Yu, K Roth, C Chen, EM Ransey, P Sliz Cell reports 18 (11), 2664-2675, 2017 | 77 | 2017 |
SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism M Shi, L Wang, P Fontana, S Vora, Y Zhang, TM Fu, J Lieberman, H Wu BioRxiv, 2020 | 70 | 2020 |
TRPM2, linking oxidative stress and Ca2+ permeation to NLRP3 inflammasome activation L Wang, R Negro, H Wu Current opinion in immunology 62, 131-135, 2020 | 63 | 2020 |
Structures and functions of the inflammasome engine L Wang, H Sharif, SM Vora, Y Zheng, H Wu Journal of Allergy and Clinical Immunology 147 (6), 2021 | 44 | 2021 |
Structural basis of regulated m7G tRNA modification by METTL1–WDR4 J Li, L Wang, Q Hahn, RP Nowak, T Viennet, EA Orellana, ... Nature 613 (7943), 391-397, 2023 | 38 | 2023 |
CG14906 (mettl4) mediates m6A methylation of U2 snRNA in Drosophila L Gu, L Wang, H Chen, J Hong, Z Shen, A Dhall, T Lao, C Liu, Z Wang, ... Cell discovery 6 (1), 44, 2020 | 36 | 2020 |
LIN28 coordinately promotes nucleolar/ribosomal functions and represses the 2C-like transcriptional program in pluripotent stem cells Z Sun, H Yu, J Zhao, T Tan, H Pan, Y Zhu, L Chen, C Zhang, L Zhang, ... Protein & Cell 13 (7), 490-512, 2022 | 33 | 2022 |
pH regulates potassium conductance and drives a constitutive proton current in human TMEM175 W Zheng, C Shen, L Wang, S Rawson, WJ Xie, C Nist-Lund, J Wu, Z Shen, ... Science advances 8 (12), eabm1568, 2022 | 29 | 2022 |
Deep-sea vent phage DNA polymerase specifically initiates DNA synthesis in the absence of primers B Zhu, L Wang, H Mitsunobu, X Lu, AJ Hernandez, Y Yoshida-Takashima, ... Proceedings of the National Academy of Sciences 114 (12), E2310-E2318, 2017 | 29 | 2017 |