Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells M Kleinewietfeld, A Manzel, J Titze, H Kvakan, N Yosef, RA Linker, ... Nature 496 (7446), 518-522, 2013 | 1494 | 2013 |
Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway RA Linker, DH Lee, S Ryan, AM van Dam, R Conrad, P Bista, W Zeng, ... Brain 134 (3), 678-692, 2011 | 1233 | 2011 |
Salt-responsive gut commensal modulates TH17 axis and disease N Wilck, MG Matus, SM Kearney, SW Olesen, K Forslund, ... Nature 551 (7682), 585-589, 2017 | 1157 | 2017 |
Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study L Kappos, A Bar-Or, BAC Cree, RJ Fox, G Giovannoni, R Gold, ... The Lancet 391 (10127), 1263-1273, 2018 | 1001 | 2018 |
Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine A Haghikia, S Jörg, A Duscha, J Berg, A Manzel, A Waschbisch, ... Immunity 43 (4), 817-829, 2015 | 884 | 2015 |
Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: a multicentre study of 175 patients S Jarius, K Ruprecht, B Wildemann, T Kuempfel, M Ringelstein, C Geis, ... Journal of neuroinflammation 9, 1-17, 2012 | 845 | 2012 |
Role of “Western diet” in inflammatory autoimmune diseases A Manzel, DN Muller, DA Hafler, SE Erdman, RA Linker, M Kleinewietfeld Current allergy and asthma reports 14, 1-8, 2014 | 567 | 2014 |
CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation RA Linker, M Mäurer, S Gaupp, R Martini, B Holtmann, R Giess, ... Nature medicine 8 (6), 620-624, 2002 | 475 | 2002 |
Propionic acid shapes the multiple sclerosis disease course by an immunomodulatory mechanism A Duscha, B Gisevius, S Hirschberg, N Yissachar, GI Stangl, E Dawin, ... Cell 180 (6), 1067-1080. e16, 2020 | 450 | 2020 |
Neuromyelitis optica: evaluation of 871 attacks and 1,153 treatment courses I Kleiter, A Gahlen, N Borisow, K Fischer, KD Wernecke, B Wegner, ... Annals of neurology 79 (2), 206-216, 2016 | 408 | 2016 |
Failure of natalizumab to prevent relapses in neuromyelitis optica I Kleiter, K Hellwig, A Berthele, T Kümpfel, RA Linker, HP Hartung, F Paul, ... Archives of neurology 69 (2), 239-245, 2012 | 339 | 2012 |
Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration S Schilling, S Goelz, R Linker, F Luehder, R Gold Clinical & Experimental Immunology 145 (1), 101-107, 2006 | 334 | 2006 |
High salt reduces the activation of IL-4–and IL-13–stimulated macrophages KJ Binger, M Gebhardt, M Heinig, C Rintisch, A Schroeder, W Neuhofer, ... The Journal of clinical investigation 125 (11), 4223-4238, 2015 | 285 | 2015 |
Impacts of microbiome metabolites on immune regulation and autoimmunity S Haase, A Haghikia, N Wilck, DN Müller, RA Linker Immunology 154 (2), 230-238, 2018 | 227 | 2018 |
Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis RA Linker, DH Lee, S Demir, S Wiese, N Kruse, I Siglienti, E Gerhardt, ... Brain 133 (8), 2248-2263, 2010 | 225 | 2010 |
Glatiramer acetate treatment normalizes deregulated microRNA expression in relapsing remitting multiple sclerosis A Waschbisch, M Atiya, RA Linker, S Potapov, S Schwab, T Derfuss PloS one 6 (9), e24604, 2011 | 216 | 2011 |
Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system J Stegbauer, DH Lee, S Seubert, G Ellrichmann, A Manzel, H Kvakan, ... Proceedings of the National Academy of Sciences 106 (35), 14942-14947, 2009 | 209 | 2009 |
Apheresis therapies for NMOSD attacks: a retrospective study of 207 therapeutic interventions I Kleiter, A Gahlen, N Borisow, K Fischer, KD Wernecke, K Hellwig, ... Neurology: Neuroimmunology & Neuroinflammation 5 (6), e504, 2018 | 206 | 2018 |
Efficacy of fumaric acid esters in the R6/2 and YAC128 models of Huntington's disease G Ellrichmann, E Petrasch-Parwez, DH Lee, C Reick, L Arning, C Saft, ... PloS one 6 (1), e16172, 2011 | 195 | 2011 |
Mechanisms of oxidative damage in multiple sclerosis and neurodegenerative diseases: therapeutic modulation via fumaric acid esters DH Lee, R Gold, RA Linker International journal of molecular sciences 13 (9), 11783-11803, 2012 | 188 | 2012 |