关注
Tristan Bepler
Tristan Bepler
Group Leader, New York Structural Biology Center
在 mit.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs
T Bepler, A Morin, M Rapp, J Brasch, L Shapiro, AJ Noble, B Berger
Nature methods 16 (11), 1153-1160, 2019
8542019
CryoDRGN: reconstruction of heterogeneous cryo-EM structures using neural networks
ED Zhong, T Bepler, B Berger, JH Davis
Nature methods 18 (2), 176-185, 2021
4482021
Learning protein sequence embeddings using information from structure
T Bepler, B Berger
7th International Conference on Learning Representations, ICLR 2019, New …, 2019
3242019
Topaz-Denoise: general deep denoising models for cryoEM and cryoET
T Bepler, K Kelley, AJ Noble, B Berger
Nature communications 11 (1), 1-12, 2020
3192020
Learning the protein language: Evolution, structure, and function
T Bepler, B Berger
Cell systems 12 (6), 654-669. e3, 2021
2942021
Human-chimpanzee differences in a FZD8 enhancer alter cell-cycle dynamics in the developing neocortex
JL Boyd, SL Skove, JP Rouanet, LJ Pilaz, T Bepler, R Gordân, GA Wray, ...
Current Biology 25 (6), 772-779, 2015
2672015
Reconstructing continuous distributions of 3D protein structure from cryo-EM images
ED Zhong, T Bepler, JH Davis, B Berger
arXiv preprint arXiv:1909.05215, 2019
1022019
Explicitly disentangling image content from rotation and translation with spatial-VAE
T Bepler, E Zhong, K Kelley, E Brignole, B Berger
Neural Informational Processing Systems (NeurIPS), 2019
97*2019
Visualization of clustered protocadherin neuronal self-recognition complexes
J Brasch, KM Goodman, AJ Noble, M Rapp, S Mannepalli, F Bahna, ...
Nature 569 (7755), 280-283, 2019
922019
Divergence in DNA specificity among paralogous transcription factors contributes to their differential in vivo binding
N Shen, J Zhao, JL Schipper, Y Zhang, T Bepler, D Leehr, J Bradley, ...
Cell systems 6 (4), 470-483. e8, 2018
552018
Distinct routes to metastasis: plasticity-dependent and plasticity-independent pathways
JA Somarelli, D Schaeffer, MS Marengo, T Bepler, D Rouse, KE Ware, ...
Oncogene 35 (33), 4302-4311, 2016
502016
Machine learning optimization of candidate antibody yields highly diverse sub-nanomolar affinity antibody libraries
L Li, E Gupta, J Spaeth, L Shing, R Jaimes, E Engelhart, R Lopez, ...
Nature Communications 14 (1), 3454, 2023
332023
An engineered protein-phosphorylation toggle network with implications for endogenous network discovery
D Mishra, T Bepler, B Teague, B Berger, J Broach, R Weiss
Science 373 (6550), eaav0780, 2021
282021
Synthetic molecular evolution of antimicrobial peptides
CH Chen, T Bepler, K Pepper, D Fu, TK Lu
Current opinion in biotechnology 75, 102718, 2022
252022
Latent Representations of Phylogeny to Predict Organism Phenotype
JN Oppenheim, T Bepler
US Patent App. 16/170,993, 2019
192019
Fully automated multi-grid cryoEM screening using Smart Leginon
A Cheng, PT Kim, H Kuang, JH Mendez, EYD Chua, K Maruthi, H Wei, ...
IUCrJ 10 (1), 77-89, 2023
182023
Learning to automate cryo-electron microscopy data collection with Ptolemy
PT Kim, AJ Noble, A Cheng, T Bepler
IUCrJ 10 (1), 90-102, 2023
172023
TOPAZ: A positive-unlabeled convolutional neural network CryoEM particle picker that can pick any size and shape particle
T Bepler, A Morin, M Rapp, J Brasch, L Shapiro, AJ Noble, B Berger
Microscopy and Microanalysis 25 (S2), 986-987, 2019
172019
PoET: A generative model of protein families as sequences-of-sequences
T Truong Jr, T Bepler
Advances in Neural Information Processing Systems 36, 2023
122023
Unsupervised Object Representation Learning using Translation and Rotation Group Equivariant VAE
A Nasiri, T Bepler
Advances in Neural Information Processing Systems, 2022
102022
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