HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1 M Beyer, A Romanski, AHM Mustafa, M Pons, I Büchler, A Vogel, A Pautz, ... Cancers 11 (10), 1436, 2019 | 33 | 2019 |
Synthesis, molecular docking and biological characterization of pyrazine linked 2-aminobenzamides as new class I selective histone deacetylase (HDAC) inhibitors with anti … HS Ibrahim, M Abdelsalam, Y Zeyn, M Zessin, AHM Mustafa, MA Fischer, ... International Journal of Molecular Sciences 23 (1), 369, 2021 | 31 | 2021 |
Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells A Rauch, A Carlstedt, C Emmerich, AHM Mustafa, A Göder, SK Knauer, ... Oncotarget 9 (45), 27835, 2018 | 26 | 2018 |
Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells M Beyer, SJ Henninger, PS Haehnel, AHM Mustafa, E Gurdal, B Schubert, ... Cell Chemical Biology 29 (3), 398-411. e4, 2022 | 16 | 2022 |
Pharmacological modulation of the crosstalk between aberrant Janus kinase signaling and epigenetic modifiers of the histone deacetylase family to treat cancer AHM Mustafa, OH Krämer Pharmacological Reviews 75 (1), 35-61, 2023 | 15 | 2023 |
Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3 V Wachholz, AHM Mustafa, Y Zeyn, SJ Henninger, M Beyer, M Dzulko, ... Archives of toxicology, 1-17, 2022 | 12 | 2022 |
Structural insights into the interaction of heme with protein tyrosine kinase JAK2 BF Schmalohr, AHM Mustafa, OH Krämer, D Imhof ChemBioChem 22 (5), 861-864, 2021 | 6 | 2021 |
Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells MA Fischer, AHM Mustafa, K Hausmann, R Ashry, AG Kansy, MC Liebl, ... Journal of Advanced Research 60, 201-214, 2024 | 4 | 2024 |
NOXA accentuates apoptosis induction by a novel histone deacetylase inhibitor R Ashry, AHM Mustafa, K Hausmann, M Linnebacher, S Strand, W Sippl, ... Cancers 15 (14), 3650, 2023 | 3 | 2023 |
Monitoring Changes in Intracellular Reactive Oxygen Species Levels in Response to Histone Deacetylase Inhibitors AHM Mustafa, R Ashry, OH Krämer HDAC/HAT Function Assessment and Inhibitor Development: Methods and …, 2022 | 1 | 2022 |
Nigella sativa oil as a protective agent for cisplatin mediated hepatotoxicity in rats AKM Abdel-Kader, MA El-Demellawy, EA Awadalla, AHM Mustafa Egypt. J. Exp. Biol 9 (2), 173-180, 2013 | 1 | 2013 |
Inhibitors of the tyrosine kinases FMS-like tyrosine kinase-3 and WEE1 induce apoptosis and DNA damage synergistically in acute myeloid leukemia cells C Hieber, AHM Mustafa, S Neuroth, S Henninger, HP Wollscheid, ... Biomedicine & Pharmacotherapy 177, 117076, 2024 | | 2024 |
The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells A Nguyen, AHM Mustafa, AK Leydecker, M Halilovic, J Murr, F Butter, ... Cell Communication and Signaling 22 (1), 217, 2024 | | 2024 |
Pharmacological degradation of ATR induces antiproliferative DNA replication stress in leukemic cells AG Kansy, R Ashry, AHM Mustafa, AM Alfayomy, MP Radsak, Y Zeyn, ... Molecular Oncology, 2024 | | 2024 |
Acetylation-dependent control of SIAH2 links JAK2V617F to mitochondrial respiration and ROS-associated apoptosis O Krämer, AH Mustafa, G Petrosino, M Fischer, L Ricciardi, D Gül, ... | | 2024 |
The protein phosphatase-2A subunit PR130 is linked to cytotoxic protein aggregate formation in mesenchymal pancreatic ductal adenocarcinoma cells OH Kramer, A Nguyen, A Leydecker, AHM Mustafa, J Murr, F Butter bioRxiv, 2023.09. 03.556106, 2023 | | 2023 |
Novel insight into mechanisms for ATR activation by chromatin structures AHM Mustafa, OH Krämer Archives of toxicology 95 (10), 3433-3434, 2021 | | 2021 |
Stability of the proactive JAK2V617F in the presence of romidepsin (FK228) in leukemic cells AHM Mustafa, OH Kramer NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 390, S60-S60, 2017 | | 2017 |