Quinoline antimalarials: mechanisms of action and resistance and prospects for new agents M Foley, L Tilley Pharmacology & therapeutics 79 (1), 55-87, 1998 | 833 | 1998 |
Oxidative stress in malaria parasite-infected erythrocytes: host–parasite interactions K Becker, L Tilley, JL Vennerstrom, D Roberts, S Rogerson, H Ginsburg International journal for parasitology 34 (2), 163-189, 2004 | 800 | 2004 |
Malaria parasite proteins that remodel the host erythrocyte AG Maier, BM Cooke, AF Cowman, L Tilley Nature Reviews Microbiology 7 (5), 341-354, 2009 | 588 | 2009 |
Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion N Klonis, MP Crespo-Ortiz, I Bottova, N Abu-Bakar, S Kenny, ... Proceedings of the National Academy of Sciences 108 (28), 11405-11410, 2011 | 451 | 2011 |
Inhibition of the peroxidative degradation of haem as the basis of action of chloroquine and other quinoline antimalarials P Loria, S Miller, M Foley, L Tilley Biochemical Journal 339 (2), 363-370, 1999 | 409 | 1999 |
Trafficking and assembly of the cytoadherence complex in Plasmodium falciparum‐infected human erythrocytes ME Wickham, M Rug, SA Ralph, N Klonis, GI McFadden, L Tilley, ... The EMBO journal, 2001 | 389 | 2001 |
Artemisinin action and resistance in Plasmodium falciparum L Tilley, J Straimer, NF Gnädig, SA Ralph, DA Fidock Trends in parasitology 32 (9), 682-696, 2016 | 387 | 2016 |
Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance C Dogovski, SC Xie, G Burgio, J Bridgford, S Mok, JM McCaw, ... PLoS biology 13 (4), e1002132, 2015 | 342 | 2015 |
Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance PG Bray, RE Martin, L Tilley, SA Ward, K Kirk, DA Fidock Molecular microbiology 56 (2), 323-333, 2005 | 294 | 2005 |
Quinoline antimalarials: mechanisms of action and resistance M Foley, L Tilley International journal for parasitology 27 (2), 231-240, 1997 | 290 | 1997 |
Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite Plasmodium falciparum JI MacRae, MWA Dixon, MK Dearnley, HH Chua, JM Chambers, S Kenny, ... BMC biology 11, 1-10, 2013 | 271 | 2013 |
Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome JL Bridgford, SC Xie, SA Cobbold, CFA Pasaje, S Herrmann, T Yang, ... Nature communications 9 (1), 3801, 2018 | 257 | 2018 |
Structure- and function-based design of Plasmodium-selective proteasome inhibitors H Li, AJ O’Donoghue, WA Van Der Linden, SC Xie, E Yoo, IT Foe, L Tilley, ... Nature 530 (7589), 233-236, 2016 | 247 | 2016 |
Digestive-vacuole genesis and endocytic processes in the early intraerythrocytic stages of Plasmodium falciparum NA Bakar, N Klonis, E Hanssen, C Chan, L Tilley Journal of cell science 123 (3), 441-450, 2010 | 242 | 2010 |
Altered temporal response of malaria parasites determines differential sensitivity to artemisinin N Klonis, SC Xie, JM McCaw, MP Crespo-Ortiz, SG Zaloumis, JA Simpson, ... Proceedings of the National Academy of Sciences 110 (13), 5157-5162, 2013 | 223 | 2013 |
Characterization of the pathway for transport of the cytoadherence‐mediating protein, PfEMP1, to the host cell surface in malaria parasite‐infected erythrocytes N Kriek, L Tilley, P Horrocks, R Pinches, BC Elford, DJP Ferguson, ... Molecular microbiology 50 (4), 1215-1227, 2003 | 219 | 2003 |
Food vacuole‐associated lipid bodies and heterogeneous lipid environments in the malaria parasite, Plasmodium falciparum KE Jackson, N Klonis, DJP Ferguson, A Adisa, C Dogovski, L Tilley Molecular microbiology 54 (1), 109-122, 2004 | 213 | 2004 |
Plasmodium species: master renovators of their host cells TF de Koning-Ward, MWA Dixon, L Tilley, PR Gilson Nature Reviews Microbiology 14 (8), 494-507, 2016 | 212 | 2016 |
Fluorescence photobleaching analysis for the study of cellular dynamics N Klonis, M Rug, I Harper, M Wickham, A Cowman, L Tilley European Biophysics Journal 31, 36-51, 2002 | 190 | 2002 |
The Plasmodium falciparum-infected red blood cell L Tilley, MWA Dixon, K Kirk The international journal of biochemistry & cell biology 43 (6), 839-842, 2011 | 185 | 2011 |