A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction G Pelicci, L Lanfrancone, F Grignani, J McGlade, F Cavallo, G Forni, ... Cell 70 (1), 93-104, 1992 | 1690 | 1992 |
Fusion proteins of the retinoic acid receptor-α recruit histone deacetylase in promyelocytic leukaemia F Grignani, S De Matteis, C Nervi, L Tomassoni, V Gelmetti, M Cioce, ... Nature 391 (6669), 815-818, 1998 | 1348 | 1998 |
The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells F Grignani, PF Ferrucci, U Testa, G Talamo, M Fagioli, M Alcalay, ... Cell 74 (3), 423-431, 1993 | 729 | 1993 |
Acute promyelocytic leukemia: from genetics to treatment F Grignani, M Fagioli, M Alcalay, L Longo, PP Pandolfi, E Donti, A Biondi, ... | 670 | 1994 |
MicroRNAs 17-5p–20a–106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation L Fontana, E Pelosi, P Greco, S Racanicchi, U Testa, F Liuzzi, CM Croce, ... Nature cell biology 9 (7), 775-787, 2007 | 591 | 2007 |
Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1 R De Maria, A Zeuner, A Eramo, C Domenichelli, D Bonci, F Grignani, ... Nature 401 (6752), 489-493, 1999 | 499 | 1999 |
Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein F Fazi, S Racanicchi, G Zardo, LM Starnes, M Mancini, L Travaglini, ... Cancer cell 12 (5), 457-466, 2007 | 497 | 2007 |
High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein F Grignani, T Kinsella, A Mencarelli, M Valtieri, D Riganelli, F Grignani, ... Cancer research 58 (1), 14-19, 1998 | 459 | 1998 |
Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties. PP Pandolfi, F Grignani, M Alcalay, A Mencarelli, A Biondi, F LoCoco, ... Oncogene 6 (7), 1285-1292, 1991 | 396 | 1991 |
N-(4-Hydroxyphenyl)retinamide Induces Apoptosis of Malignant Hemopoietic Cell Lines Including Those Unresponsive to Retinoic Acid D Delia, A Aiello, L Lombardi, PG Pelicci, F Grignani, F Grignani, ... Cancer Research 53 (24), 6036-6041, 1993 | 326 | 1993 |
Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane: retention of caveolin-2 at the level of the golgi complex I Parolini, M Sargiacomo, F Galbiati, G Rizzo, F Grignani, JA Engelman, ... Journal of Biological Chemistry 274 (36), 25718-25725, 1999 | 281 | 1999 |
A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis C Labbaye, I Spinello, MT Quaranta, E Pelosi, L Pasquini, E Petrucci, ... Nature Cell Biology 10 (7), 788-801, 2008 | 276 | 2008 |
Caspases mediate retinoic acid–induced degradation of the acute promyelocytic leukemia PML/RARα fusion protein C Nervi, FF Ferrara, M Fanelli, MR Rippo, B Tomassini, PF Ferrucci, ... Blood, The Journal of the American Society of Hematology 92 (7), 2244-2251, 1998 | 246 | 1998 |
The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein M Alcalay, L Tomassoni, E Colombo, S Stoldt, F Grignani, M Fagioli, ... Molecular and cellular biology 18 (2), 1084-1093, 1998 | 238 | 1998 |
Down-regulation of LFA-1 adhesion receptors by C-myc oncogene in human B lymphoblastoid cells G Inghirami, F Grignani, L Sternas, L Lombardi, DM Knowles, ... Science 250 (4981), 682-686, 1990 | 197 | 1990 |
Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression G Zardo, A Ciolfi, L Vian, LM Starnes, M Billi, S Racanicchi, C Maresca, ... Blood, The Journal of the American Society of Hematology 119 (17), 4034-4046, 2012 | 187 | 2012 |
Growth-and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells. G Nunez, M Seto, S Seremetis, D Ferrero, F Grignani, SJ Korsmeyer, ... Proceedings of the National Academy of Sciences 86 (12), 4589-4593, 1989 | 175 | 1989 |
Human CD4 lymphocytes specifically recognize a peptide representing the fusion region of the hybrid protein pml/RAR alpha present in acute promyelocytic leukemia cells C Gambacorti-Passerini, F Grignani, F Arienti, PP Pandolfi, PG Pelicci, ... | 159 | 1993 |
Effects on differentiation by the promyelocytic leukemia PML/RARalpha protein depend on the fusion of the PML protein dimerization and RARalpha DNA binding domains. F Grignani, U Testa, D Rogaia, PF Ferrucci, P Samoggia, A Pinto, ... The EMBO Journal 15 (18), 4949-4958, 1996 | 153 | 1996 |
Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor α (RARα) and PLZF-RARα fusion proteins on retinoic acid signalling M Ruthardt, U Testa, C Nervi, PF Ferrucci, F Grignani, E Puccetti, ... Molecular and cellular biology 17 (8), 4859-4869, 1997 | 151 | 1997 |