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angelo pugliese
angelo pugliese
Assoc. Director, Head In Silico Discovery at BioAscent
在 bioascent.com 的电子邮件经过验证 - 首页
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引用次数
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年份
[6]-Gingerol suppresses colon cancer growth by targeting leukotriene A4 hydrolase
CH Jeong, AM Bode, A Pugliese, YY Cho, HG Kim, JH Shim, YJ Jeon, ...
Cancer research 69 (13), 5584-5591, 2009
2882009
Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine
KW Lee, NJ Kang, YS Heo, EA Rogozin, A Pugliese, MK Hwang, ...
Cancer research 68 (3), 946-955, 2008
2422008
Software and resources for computational medicinal chemistry
C Liao, M Sitzmann, A Pugliese, MC Nicklaus
Future medicinal chemistry 3 (8), 1057-1085, 2011
2102011
Fragment-based hit identification: thinking in 3D
AD Morley, A Pugliese, K Birchall, J Bower, P Brennan, N Brown, ...
Drug Discovery Today 18 (23-24), 1221-1227, 2013
1872013
Resveratrol, a Red Wine Polyphenol, Suppresses Pancreatic Cancer by Inhibiting Leukotriene A4 Hydrolase
N Oi, CH Jeong, J Nadas, YY Cho, A Pugliese, AM Bode, Z Dong
Cancer Research 70 (23), 9755-9764, 2010
1242010
(-)-Epigallocatechin gallate regulates CD3-mediated T cell receptor signaling in leukemia through the inhibition of ZAP-70 kinase
JH Shim, HS Choi, A Pugliese, SY Lee, JI Chae, BY Choi, AM Bode, ...
Journal of Biological Chemistry 283 (42), 28370-28379, 2008
1242008
A regulatory mechanism for RSK2 NH2-terminal kinase activity
YY Cho, K Yao, A Pugliese, ML Malakhova, AM Bode, Z Dong
Cancer research 69 (10), 4398-4406, 2009
782009
Computational tools and resources for metabolism-related property predictions. 1. Overview of publicly available (free and commercial) databases and software
ML Peach, AV Zakharov, R Liu, A Pugliese, G Tawa, A Wallqvist, ...
Future medicinal chemistry 4 (15), 1907-1932, 2012
682012
Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformation
K Liu, YY Cho, K Yao, J Nadas, DJ Kim, EJ Cho, MH Lee, A Pugliese, ...
Journal of Biological Chemistry 286 (3), 2057-2066, 2011
682011
Cyclin-dependent kinase-3–mediated c-Jun phosphorylation at Ser63 and Ser73 enhances cell transformation
YY Cho, F Tang, K Yao, C Lu, F Zhu, D Zheng, A Pugliese, AM Bode, ...
Cancer research 69 (1), 272-281, 2009
612009
Role of NEK6 in tumor promoter-induced transformation in JB6 C141 mouse skin epidermal cells
YJ Jeon, KY Lee, YY Cho, A Pugliese, HG Kim, CH Jeong, AM Bode, ...
Journal of Biological Chemistry 285 (36), 28126-28133, 2010
462010
Herbacetin is a novel allosteric inhibitor of ornithine decarboxylase with antitumor activity
DJ Kim, E Roh, MH Lee, N Oi, DY Lim, MO Kim, YY Cho, A Pugliese, ...
Cancer research 76 (5), 1146-1157, 2016
412016
Anti-cancer gallotannin penta-O-galloyl-beta-D-glucose is a nanomolar inhibitor of select mammalian DNA polymerases
Y Mizushina, J Zhang, A Pugliese, SH Kim, J Lü
Biochemical pharmacology 80 (8), 1125-1132, 2010
392010
Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo [4, 3-c] pyridine inhibitors of fascin 1 as potential anti-metastatic …
S Francis, D Croft, AW Schüttelkopf, C Parry, A Pugliese, K Cameron, ...
Bioorganic & Medicinal Chemistry Letters 29 (8), 1023-1029, 2019
382019
Computational tools and resources for metabolism-related property predictions. 2. Application to prediction of half-life time in human liver microsomes
AV Zakharov, ML Peach, M Sitzmann, IV Filippov, HJ McCartney, ...
Future medicinal chemistry 4 (15), 1933-1944, 2012
352012
The resveratrol analogue 3, 5, 3′, 4′, 5′‐pentahydroxy‐trans‐stilbene inhibits cell transformation via MEK
KW Lee, NJ Kang, EA Rogozin, SM Oh, YS Heo, A Pugliese, AM Bode, ...
International journal of cancer 123 (11), 2487-2496, 2008
352008
Identification of a selective G1-phase benzimidazolone inhibitor by a senescence-targeted virtual screen using artificial neural networks
AE Bilsland, A Pugliese, Y Liu, J Revie, S Burns, C McCormick, ...
Neoplasia 17 (9), 704-715, 2015
222015
Automated generation of novel fragments using screening data, a dual SMILES autoencoder, transfer learning and syntax correction
AE Bilsland, K McAulay, R West, A Pugliese, J Bower
Journal of Chemical Information and Modeling 61 (6), 2547-2559, 2021
182021
Access to 3D Alicyclic Amine-Containing Fragments through Transannular C–H Arylation
M Lee, A Adams, PB Cox, MS Sanford
Synlett 30 (04), 417-422, 2019
172019
Stabilization of the ras: Pde6d complex is a novel strategy to inhibit ras signaling
T Yelland, E Garcia, C Parry, D Kowalczyk, M Wojnowska, A Gohlke, ...
Journal of Medicinal Chemistry 65 (3), 1898-1914, 2022
122022
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