Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage Y Bollen, JH Hageman, P van Leenen, LLM Derks, B Ponsioen, ... PLoS Biology 20 (1), e3001527, 2022 | 13 | 2022 |
One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids MH Geurts, S Gandhi, MG Boretto, N Akkerman, LLM Derks, G van Son, ... Nature Communications 14 (1), 4998, 2023 | 10 | 2023 |
Stem cell mutations, associated cancer risk, and consequences for regenerative medicine LLM Derks, R van Boxtel Cell Stem Cell, 2023 | 6 | 2023 |
Comprehensive single-cell genome analysis at nucleotide resolution using the PTA Analysis Toolbox S Middelkamp, F Manders, F Peci, MJ van Roosmalen, DM González, ... Cell Genomics 3 (9), 2023 | 5 | 2023 |
Protocol to create isogenic disease models from adult stem cell-derived organoids using next-generation CRISPR tools M Celotti, LLM Derks, J van Es, R van Boxtel, H Clevers, MH Geurts STAR protocols 5 (3), 103189, 2024 | | 2024 |
Selective pressures of platinum compounds shape the evolution of therapy-related myeloid neoplasms EJM Bertrums, JK de Kanter, LLM Derks, M Verheul, L Trabut, ... Nature Communications 15 (1), 6025, 2024 | | 2024 |
Cell division‐dependent dissemination following E‐cadherin loss underlies initiation of diffuse‐type gastric cancer JL Monster, LJS Kemp, GA Busslinger, MJ Vliem, LLM Derks, AAL Staes, ... The Journal of Pathology 263 (2), 226-241, 2024 | | 2024 |
Single-Cell Whole-Genome Sequencing after Chemotherapeutic Treatment Reveals Cell Type-Specific Mutational Burdens LLM Derks, I Van Der Werf, L Trabut, E Bertrums, J De Kanter, AR Huber, ... Blood 142, 4136, 2023 | | 2023 |