Tryprostatin A, a specific and novel inhibitor of microtubule assembly T Usui, M Kondoh, CB Cui, T Mayumi, H OSADA Biochemical Journal 333 (3), 543-548, 1998 | 286 | 1998 |
Yeast Cdk1 translocates to the plus end of cytoplasmic microtubules to regulate bud cortex interactions H Maekawa, T Usui, M Knop, E Schiebel The EMBO journal, 2003 | 190 | 2003 |
Laforin, defective in the progressive myoclonus epilepsy of Lafora type, is a dual-specificity phosphatase associated with polyribosomes S Ganesh, KL Agarwala, K Ueda, T Akagi, K Shoda, T Usui, T Hashikawa, ... Human molecular genetics 9 (15), 2251-2261, 2000 | 178 | 2000 |
Highly synchronous culture of fibroblasts from G2 block caused by staurosporine, a potent inhibitor of protein kinases K Abe, M Yoshida, T Usui, S Horinouchi, T Beppu Experimental cell research 192 (1), 122-127, 1991 | 160 | 1991 |
Uncoupled cell cycle without mitosis induced by a protein kinase inhibitor, K-252a. T Usui, M Yoshida, K Abe, H Osada, K Isono, T Beppu The Journal of cell biology 115 (5), 1275-1282, 1991 | 152 | 1991 |
Asymmetric, stereocontrolled total synthesis of (+) and (−)-spirotryprostatin B via a diastereoselective azomethine ylide [1, 3]-dipolar cycloaddition reaction PR Sebahar, H Osada, T Usui, RM Williams Tetrahedron 58 (32), 6311-6322, 2002 | 150 | 2002 |
A novel action of terpendole E on the motor activity of mitotic Kinesin Eg5 J Nakazawa, J Yajima, T Usui, M Ueki, A Takatsuki, M Imoto, ... Chemistry & Biology 10 (2), 131-137, 2003 | 146 | 2003 |
The anticancer natural product pironetin selectively targets Lys352 of α-tubulin T Usui, H Watanabe, H Nakayama, Y Tada, N Kanoh, M Kondoh, T Asao, ... Chemistry & biology 11 (6), 799-806, 2004 | 135 | 2004 |
Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual-specificity protein phosphatases and its evaluation regarding VHR and cdc25B inhibition M Sodeoka, R Sampe, S Kojima, Y Baba, T Usui, K Ueda, H Osada Journal of medicinal chemistry 44 (20), 3216-3222, 2001 | 127 | 2001 |
Synthesis and structure–activity relationship study of antimicrotubule agents Phenylahistin derivatives with a Didehydropiperazine-2, 5-dione structure Y Yamazaki, K Tanaka, B Nicholson, G Deyanat-Yazdi, B Potts, T Yoshida, ... Journal of medicinal chemistry 55 (3), 1056-1071, 2012 | 126 | 2012 |
Cell cycle arrest and antitumor activity of pironetin and its derivatives M Kondoh, T Usui, S Kobayashi, K Tsuchiya, K Nishikawa, T Nishikiori, ... Cancer letters 126 (1), 29-32, 1998 | 122 | 1998 |
Isolation of New Protein Phosphatase Inhibitors from Two Cyanobacteria Species, Planktothrix spp. T Sano, T Usui, K Ueda, H Osada, K Kaya Journal of natural products 64 (8), 1052-1055, 2001 | 117 | 2001 |
Synthesis and evaluation of tryprostatin B and demethoxyfumitremorgin C analogues H Wang, T Usui, H Osada, A Ganesan Journal of medicinal chemistry 43 (8), 1577-1585, 2000 | 106 | 2000 |
Identification of Cytochrome P450s Required for Fumitremorgin Biosynthesis in Aspergillus fumigatus N Kato, H Suzuki, H Takagi, Y Asami, H Kakeya, M Uramoto, T Usui, ... ChemBioChem 10 (5), 920-928, 2009 | 102 | 2009 |
Application of proteomic profiling based on 2D-DIGE for classification of compounds according to the mechanism of action M Muroi, S Kazami, K Noda, H Kondo, H Takayama, M Kawatani, T Usui, ... Chemistry & biology 17 (5), 460-470, 2010 | 96 | 2010 |
Apoptosis induction via microtubule disassembly by an antitumour compound, pironetin M KONDOH, T USUI, T NISHIKIORI, T MAYUMI, H OSADA Biochemical Journal 340 (2), 411-416, 1999 | 96 | 1999 |
Amphidinolide H, a potent cytotoxic macrolide, covalently binds on actin subdomain 4 and stabilizes actin filament T Usui, S Kazami, N Dohmae, Y Mashimo, H Kondo, M Tsuda, ... Chemistry & biology 11 (9), 1269-1277, 2004 | 94 | 2004 |
The XMAP215 homologue Stu2 at yeast spindle pole bodies regulates microtubule dynamics and anchorage T Usui, H Maekawa, G Pereira, E Schiebel The EMBO journal, 2003 | 93 | 2003 |
Identification of Saccharomyces cerevisiae isoleucyl-tRNA synthetase as a target of the G1-specific inhibitor Reveromycin A Y Miyamoto, K Machida, M Mizunuma, Y Emoto, N Sato, K Miyahara, ... Journal of Biological Chemistry 277 (32), 28810-28814, 2002 | 88 | 2002 |
Inhibition of microtubule assembly by a complex of actin and antitumor macrolide aplyronine A M Kita, Y Hirayama, K Yoneda, K Yamagishi, T Chinen, T Usui, E Sumiya, ... Journal of the American Chemical Society 135 (48), 18089-18095, 2013 | 75 | 2013 |