| Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases, cysteine, and serine proteases REK Russell, A Thorley, SV Culpitt, S Dodd, LE Donnelly, C Demattos, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 283 (4 …, 2002 | 400 | 2002 |
| Differential regulation of cytokine release and leukocyte migration by lipopolysaccharide-stimulated primary human lung alveolar type II epithelial cells and macrophages AJ Thorley, PA Ford, MA Giembycz, P Goldstraw, A Young, TD Tetley The journal of immunology 178 (1), 463-473, 2007 | 252 | 2007 |
| Diminished prostaglandin E2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosis TM Maher, IC Evans, SE Bottoms, PF Mercer, AJ Thorley, AG Nicholson, ... American journal of respiratory and critical care medicine 182 (1), 73-82, 2010 | 229 | 2010 |
| Pulmonary epithelium, cigarette smoke, and chronic obstructive pulmonary disease AJ Thorley, TD Tetley International journal of chronic obstructive pulmonary disease 2 (4), 409-428, 2007 | 212 | 2007 |
| New perspectives in nanomedicine AJ Thorley, TD Tetley Pharmacology & therapeutics 140 (2), 176-185, 2013 | 208 | 2013 |
| Immortalization of human alveolar epithelial cells to investigate nanoparticle uptake SJ Kemp, AJ Thorley, J Gorelik, MJ Seckl, MJ O'Hare, A Arcaro, Y Korchev, ... American Journal of Respiratory Cell and Molecular Biology 39 (5), 591-597, 2008 | 170 | 2008 |
| Respiratory epithelial cytotoxicity and membrane damage (holes) caused by amine-modified nanoparticles P Ruenraroengsak, P Novak, D Berhanu, AJ Thorley, E Valsami-Jones, ... Nanotoxicology 6 (1), 94-108, 2012 | 154 | 2012 |
| Nanotechnology in the diagnosis and treatment of lung cancer AM Cryer, AJ Thorley Pharmacology & therapeutics 198, 189-205, 2019 | 147 | 2019 |
| Pulmonary epithelium is a prominent source of proteinase-activated receptor-1–inducible CCL2 in pulmonary fibrosis PF Mercer, RH Johns, CJ Scotton, MA Krupiczojc, M Königshoff, ... American journal of respiratory and critical care medicine 179 (5), 414-425, 2009 | 147 | 2009 |
| Critical determinants of uptake and translocation of nanoparticles by the human pulmonary alveolar epithelium AJ Thorley, P Ruenraroengsak, TE Potter, TD Tetley Acs Nano 8 (11), 11778-11789, 2014 | 142 | 2014 |
| Innate immune responses to bacterial ligands in the peripheral human lung–role of alveolar epithelial TLR expression and signalling AJ Thorley, D Grandolfo, E Lim, P Goldstraw, A Young, TD Tetley PloS one 6 (7), e21827, 2011 | 115 | 2011 |
| Primary human alveolar type II epithelial cell CCL20 (macrophage inflammatory protein-3α)–induced dendritic cell migration AJ Thorley, P Goldstraw, A Young, TD Tetley American Journal of Respiratory Cell and Molecular Biology 32 (4), 262-267, 2005 | 109 | 2005 |
| Cytotoxicity and cellular mechanisms of toxicity of CuO NPs in mussel cells in vitro and comparative sensitivity with human cells A Katsumiti, AJ Thorley, I Arostegui, P Reip, E Valsami-Jones, TD Tetley, ... Toxicology in Vitro 48, 146-158, 2018 | 101 | 2018 |
| Imaging single nanoparticle interactions with human lung cells using fast ion conductance microscopy P Novak, A Shevchuk, P Ruenraroengsak, M Miragoli, AJ Thorley, ... Nano letters 14 (3), 1202-1207, 2014 | 101* | 2014 |
| Sulfidation of silver nanowires inside human alveolar epithelial cells: a potential detoxification mechanism S Chen, AE Goode, S Sweeney, IG Theodorou, AJ Thorley, ... Nanoscale 5 (20), 9839-9847, 2013 | 70 | 2013 |
| Microphysiological lung models to evaluate the safety of new pharmaceutical modalities: a biopharmaceutical perspective GR Ainslie, M Davis, L Ewart, LA Lieberman, DJ Rowlands, AJ Thorley, ... Lab on a Chip 19 (19), 3152-3161, 2019 | 57 | 2019 |
| The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis F Conforti, ER Davies, CJ Calderwood, TH Thatcher, MG Jones, DE Smart, ... Oncotarget 8 (30), 48737, 2017 | 55 | 2017 |
| Multi-walled carbon nanotube length as a critical determinant of bioreactivity with primary human pulmonary alveolar cells S Sweeney, D Berhanu, SK Misra, AJ Thorley, E Valsami-Jones, ... Carbon 78, 26-37, 2014 | 52 | 2014 |
| Aqueous cationic, anionic and non-ionic multi-walled carbon nanotubes, functionalised with minimal framework damage, for biomedical application S Chen, S Hu, EF Smith, P Ruenraroengsak, AJ Thorley, R Menzel, ... Biomaterials 35 (17), 4729-4738, 2014 | 50 | 2014 |
| Inflammatory response and barrier properties of a new alveolar type 1-like cell line (TT1) EHJ van den Bogaard, LA Dailey, AJ Thorley, TD Tetley, B Forbes Pharmaceutical research 26, 1172-1180, 2009 | 41 | 2009 |
