Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype DW Threadgill, AA Dlugosz, LA Hansen, T Tennenbaum, U Lichti, D Yee, ... Science 269 (5221), 230-234, 1995 | 1791 | 1995 |
Essential Role forSonic hedgehogduring hair follicle morphogenesis C Chiang, RZ Swan, M Grachtchouk, M Bolinger, Y Litingtung, ... Developmental biology 205 (1), 1-9, 1999 | 596 | 1999 |
Primary cilia can both mediate and suppress Hedgehog pathway–dependent tumorigenesis SY Wong, AD Seol, PL So, AN Ermilov, CK Bichakjian, EH Epstein Jr, ... Nature medicine 15 (9), 1055-1061, 2009 | 528 | 2009 |
Basal cell carcinomas in mice overexpressing Gli2 in skin M Grachtchouk, R Mo, S Yu, X Zhang, H Sasaki, C Hui, AA Dlugosz Nature genetics 24 (3), 216-217, 2000 | 480 | 2000 |
Dual and opposing roles of primary cilia in medulloblastoma development YG Han, HJ Kim, AA Dlugosz, DW Ellison, RJ Gilbertson, A Alvarez-Buylla Nature medicine 15 (9), 1062-1065, 2009 | 454 | 2009 |
Wnt/β-catenin signaling directs multiple stages of tooth morphogenesis F Liu, EY Chu, B Watt, Y Zhang, NM Gallant, T Andl, SH Yang, MM Lu, ... Developmental biology 313 (1), 210-224, 2008 | 451 | 2008 |
Genomic analysis of smoothened inhibitor resistance in basal cell carcinoma HJ Sharpe, G Pau, GJ Dijkgraaf, N Basset-Seguin, Z Modrusan, ... Cancer cell 27 (3), 327-341, 2015 | 408 | 2015 |
Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches SC Peterson, M Eberl, AN Vagnozzi, A Belkadi, NA Veniaminova, ... Cell stem cell 16 (4), 400-412, 2015 | 375 | 2015 |
Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development P Mill, R Mo, H Fu, M Grachtchouk, PCW Kim, AA Dlugosz, C Hui Genes & development 17 (2), 282-294, 2003 | 367 | 2003 |
Hedgehog/Ras interactions regulate early stages of pancreatic cancer MP Di Magliano, S Sekine, A Ermilov, J Ferris, AA Dlugosz, M Hebrok Genes & development 20 (22), 3161-3173, 2006 | 354 | 2006 |
Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle ME Hutchin, MST Kariapper, M Grachtchouk, A Wang, L Wei, ... Genes & development 19 (2), 214-223, 2005 | 338 | 2005 |
TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation X Cheng, J Jin, L Hu, D Shen, X Dong, MA Samie, J Knoff, B Eisinger, ... Cell 141 (2), 331-343, 2010 | 333 | 2010 |
The distinctive mutational spectra of polyomavirus-negative Merkel cell carcinoma PW Harms, P Vats, ME Verhaegen, DR Robinson, YM Wu, ... Cancer research 75 (18), 3720-3727, 2015 | 330 | 2015 |
Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase C. AA Dlugosz, SH Yuspa The Journal of cell biology 120 (1), 217-225, 1993 | 308 | 1993 |
Transient activation of β-catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice D Van Mater, FT Kolligs, AA Dlugosz, ER Fearon Genes & development 17 (10), 1219-1224, 2003 | 300 | 2003 |
The relationship between stress fiber-like structures and nascent myofibrils in cultured cardiac myocytes. AA Dlugosz, PB Antin, VT Nachmias, H Holtzer The Journal of cell biology 99 (6), 2268-2278, 1984 | 297 | 1984 |
Loss of functional ELOVL4 depletes very long-chain fatty acids (≥ C28) and the unique ω-O-acylceramides in skin leading to neonatal death V Vasireddy, Y Uchida, N Salem Jr, SY Kim, MNA Mandal, GB Reddy, ... Human molecular genetics 16 (5), 471-482, 2007 | 292 | 2007 |
Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin D DePianto, ML Kerns, AA Dlugosz, PA Coulombe Nature genetics 42 (10), 910-914, 2010 | 284 | 2010 |
Common activation of canonical Wnt signaling in pancreatic adenocarcinoma M Pasca di Magliano, AV Biankin, PW Heiser, DA Cano, PJA Gutierrez, ... PloS one 2 (11), e1155, 2007 | 279 | 2007 |
Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development. LA Hansen, N Alexander, ME Hogan, JP Sundberg, A Dlugosz, ... The American journal of pathology 150 (6), 1959, 1997 | 271 | 1997 |