Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes D Chiabrando, F Vinchi, V Fiorito, S Mercurio, E Tolosano Frontiers in pharmacology 5, 61, 2014 | 443 | 2014 |
Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position− 7007 of the FPN1 promoter S Marro, D Chiabrando, E Messana, J Stolte, E Turco, E Tolosano, ... haematologica 95 (8), 1261, 2010 | 291 | 2010 |
The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation D Chiabrando, S Marro, S Mercurio, C Giorgi, S Petrillo, F Vinchi, V Fiorito, ... The Journal of clinical investigation 122 (12), 4569-4579, 2012 | 212 | 2012 |
Heme and erythropoieis: more than a structural role D Chiabrando, S Mercurio, E Tolosano haematologica 99 (6), 973, 2014 | 191 | 2014 |
The multifaceted role of heme in cancer V Fiorito, D Chiabrando, S Petrillo, F Bertino, E Tolosano Frontiers in oncology 9, 1540, 2020 | 112 | 2020 |
Heme accumulation in endothelial cells impairs angiogenesis by triggering paraptosis S Petrillo, D Chiabrando, T Genova, V Fiorito, G Ingoglia, F Vinchi, ... Cell Death & Differentiation 25 (3), 573-588, 2018 | 99 | 2018 |
Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450 F Vinchi, G Ingoglia, D Chiabrando, S Mercurio, E Turco, L Silengo, ... Gastroenterology 146 (5), 1325-1338, 2014 | 76 | 2014 |
The heme exporter Flvcr1 regulates expansion and differentiation of committed erythroid progenitors by controlling intracellular heme accumulation S Mercurio, S Petrillo, D Chiabrando, ZI Bassi, D Gays, A Camporeale, ... haematologica 100 (6), 720, 2015 | 70 | 2015 |
Mutations in the Heme Exporter FLVCR1 Cause Sensory Neurodegeneration with Loss of Pain Perception D Chiabrando, M Castori, M di Rocco, M Ungelenk, S Gießelmann, ... PLoS genetics 12 (12), e1006461, 2016 | 64 | 2016 |
Unraveling the role of heme in neurodegeneration D Chiabrando, V Fiorito, S Petrillo, E Tolosano Frontiers in neuroscience 12, 712, 2018 | 56 | 2018 |
The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation V Fiorito, AL Allocco, S Petrillo, E Gazzano, S Torretta, S Marchi, ... Cell reports 35 (11), 2021 | 48 | 2021 |
Lack of haptoglobin affects iron transport across duodenum by modulating ferroportin expression S Marro, D Barisani, D Chiabrando, S Fagoonee, MU Muckenthaler, ... Gastroenterology 133 (4), 1261-1271. e3, 2007 | 39 | 2007 |
Fyn kinase is a novel modulator of erythropoietin signaling and stress erythropoiesis E Beneduce, A Matte, L De Falco, S Mbiandjeu, D Chiabrando, ... American journal of hematology 94 (1), 10-20, 2019 | 36 | 2019 |
Diamond Blackfan anemia at the crossroad between ribosome biogenesis and heme metabolism D Chiabrando, E Tolosano Advances in Hematology 2010 (1), 790632, 2010 | 36 | 2010 |
Mitochondrial targeting in neurodegeneration: a heme perspective V Fiorito, D Chiabrando, E Tolosano Pharmaceuticals 11 (3), 87, 2018 | 34 | 2018 |
Haptoglobin and hemopexin in heme detoxification and iron recycling D Chiabrando, F Vinchi, V Fiorito, E Tolosano Acute Phase Proteins-Regulation and Functions of Acute Phase Proteins, 261-288, 2011 | 29 | 2011 |
Posterior column ataxia with retinitis pigmentosa coexisting with sensory‐autonomic neuropathy and leukemia due to the homozygous p. Pro221Ser FLVCR1 mutation M Castori, S Morlino, M Ungelenk, D Pareyson, E Salsano, P Grammatico, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 174 …, 2017 | 28 | 2017 |
Alteration of heme metabolism in a cellular model of Diamond–Blackfan anemia S Mercurio, A Aspesi, L Silengo, F Altruda, I Dianzani, D Chiabrando European Journal of Haematology 96 (4), 367-374, 2016 | 26 | 2016 |
Cell-specific regulation of Ferroportin transcription following experimentally-induced acute anemia in mice D Chiabrando, V Fiorito, S Marro, L Silengo, F Altruda, E Tolosano Blood Cells, Molecules, and Diseases 50 (1), 25-30, 2013 | 26 | 2013 |
Heme and sensory neuropathy: insights from novel mutations in the heme exporter feline leukemia virus subgroup C receptor 1 F Bertino, K Firestone, E Bellacchio, KE Jackson, A Asamoah, J Hersh, ... Pain 160 (12), 2766-2775, 2019 | 23 | 2019 |