The application of isatin-based multicomponent-reactions in the quest for new bioactive and druglike molecules P Brandão, C Marques, AJ Burke, M Pineiro European Journal of Medicinal Chemistry 211, 113102, 2021 | 87 | 2021 |
Recent advances in the asymmetric catalytic synthesis of chiral 3-hydroxy and 3-aminooxindoles and derivatives: Medicinally relevant compounds P Brandão, AJ Burke Tetrahedron 74 (38), 4927-4957, 2018 | 39 | 2018 |
Engaging Isatins in Multicomponent Reactions (MCRs) – Easy Access to Structural Diversity P Brandão, CS Marques, EP Carreiro, M Pineiro, AJ Burke The Chemical Record, 2021 | 35 | 2021 |
Resolution and determination of enantiomeric purity of new chiral derivatives of xanthones using polysaccharide-based stationary phases C Fernandes, P Brandão, A Santos, ME Tiritan, C Afonso, QB Cass, ... Journal of Chromatography A 1269, 143-153, 2012 | 34 | 2012 |
Drug-like properties and ADME of xanthone derivatives: The antechamber of clinical trials A Sara Gomes, P Brandão, C Sofia Garcia Fernandes, ... Current medicinal chemistry 23 (32), 3654-3686, 2016 | 31 | 2016 |
Flow Chemistry: Towards A More Sustainable Heterocyclic Synthesis P Brandão, M Pineiro, TMVD Pinho e Melo European Journal of Organic Chemistry 2019 (43), 7188–7217, 2019 | 30 | 2019 |
Targeting the MDM2-p53 protein-protein interaction with prenylchalcones: Synthesis of a small library and evaluation of potential antitumor activity P Brandão, JB Loureiro, S Carvalho, MH Hamadou, S Cravo, J Moreira, ... European Journal of Medicinal Chemistry 156, 711-721, 2018 | 29 | 2018 |
Synthesis, Biological Evaluation, and In Silico Studies of Novel Aminated Xanthones as Potential p53-Activating Agents A Lemos, AS Gomes, JB Loureiro, P Brandão, A Palmeira, MMM Pinto, ... Molecules 24 (10), 1975, 2019 | 24 | 2019 |
A decade of Indium‐catalyzed multicomponent reactions (MCRs) P Brandão, AJ Burke, M Pineiro European Journal of Organic Chemistry, 2020 | 21 | 2020 |
Ugi Reaction Synthesis of Oxindole–Lactam Hybrids as Selective Butyrylcholinesterase Inhibitors P Brandão, Ó López, L Leitzbach, H Stark, JG Fernández-Bolaños, ... ACS Medicinal Chemistry Letters, 2021 | 17 | 2021 |
I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin P Brandão, D Pinheiro, JS Seixas de Melo, M Pineiro Dyes and Pigments 173, 2020 | 17 | 2020 |
Prenylated chalcone 2 acts as an antimitotic agent and enhances the chemosensitivity of tumor cells to paclitaxel J Fonseca, S Marques, P Silva, P Brandão, H Cidade, MM Pinto, ... Molecules 21 (8), 982, 2016 | 17 | 2016 |
DARK Classics in Chemical Neuroscience: Bucinnazine K Resnik, P Brandão, EA Alves ACS Chemical Neuroscience, 2021 | 14 | 2021 |
Repeated subcutaneous administrations of krokodil causes skin necrosis and internal organs toxicity in Wistar rats: putative human implications EA Alves, P Brandão, JF Neves, SM Cravo, JX Soares, JPC Grund, ... Human Psychopharmacology: Clinical and Experimental 32 (3), e2572, 2017 | 14 | 2017 |
Tryptanthrin from indigo: Synthesis, excited state deactivation routes and efficient singlet oxygen sensitization D Pinheiro, M Pineiro, J Pina, P Brandão, AM Galvão, JSS de Melo Dyes and Pigments 175, 108125, 2020 | 12 | 2020 |
Petasis adducts of tryptanthrin – synthesis, biological activity evaluation and druglikeness assessment P Brandão, C Marques, E Pinto, M Pineiro, AJ Burke New Journal of Chemistry, 2021 | 11 | 2021 |
Ugi adducts of isatin as promising antiproliferative agents with druglike properties MP Pedro Brandão, Adrián Puerta, José M Padrón, Maxim L Kuznetsov, Anthony J ... Asian Journal of Organic Chemistry, 2021 | 8 | 2021 |
Norhierridin B, a New Hierridin B-Based Hydroquinone with Improved Antiproliferative Activity P Brandão, J Moreira, J Almeida, N Nazareth, IE Sampaio-Dias, ... Molecules 25 (7), 1578, 2020 | 6 | 2020 |
Nanocarriers in Tuberculosis Treatment: Challenges and Delivery Strategies M Kumar, T Virmani, G Kumar, R Deshmukh, A Sharma, S Duarte, ... Pharmaceuticals 16 (10), 1360, 2023 | 5 | 2023 |
Tryptanthrin and Its Derivatives in Drug Discovery: Synthetic Insights P Brandão, M Pineiro, AJ Burke Synthesis, 2022 | 5 | 2022 |