| Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody W Yin, Y Xu, P Xu, X Cao, C Wu, C Gu, X He, X Wang, S Huang, Q Yuan, ... Science 375 (6584), 1048-1053, 2022 | 148 | 2022 |
| Structural insights into the lipid and ligand regulation of serotonin receptors P Xu, S Huang, H Zhang, C Mao, XE Zhou, X Cheng, IA Simon, DD Shen, ... Nature 592 (7854), 469-473, 2021 | 106 | 2021 |
| Structural insights into the human D1 and D2 dopamine receptor signaling complexes Y Zhuang, P Xu, C Mao, L Wang, B Krumm, XE Zhou, S Huang, H Liu, ... Cell 184 (4), 931-942. e18, 2021 | 98 | 2021 |
| Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy J Duan, D Shen, XE Zhou, P Bi, Q Liu, Y Tan, Y Zhuang, H Zhang, P Xu, ... Nature communications 11 (1), 4121, 2020 | 94 | 2020 |
| Structures of the human dopamine D3 receptor-Gi complexes P Xu, S Huang, C Mao, BE Krumm, XE Zhou, Y Tan, XP Huang, Y Liu, ... Molecular Cell 81 (6), 1147-1159. e4, 2021 | 44 | 2021 |
| Structures of full-length glycoprotein hormone receptor signalling complexes J Duan, P Xu, X Cheng, C Mao, T Croll, X He, J Shi, X Luan, W Yin, E You, ... Nature 598 (7882), 688-692, 2021 | 39 | 2021 |
| Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors F Zhao, Q Zhou, Z Cong, K Hang, X Zou, C Zhang, Y Chen, A Dai, A Liang, ... Nature Communications 13 (1), 1057, 2022 | 32 | 2022 |
| Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor Y Wang, S Guo, Y Zhuang, Y Yun, P Xu, X He, J Guo, W Yin, HE Xu, X Xie, ... Nature Communications 12 (1), 5064, 2021 | 29 | 2021 |
| Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor Z Cong, LN Chen, H Ma, Q Zhou, X Zou, C Ye, A Dai, Q Liu, W Huang, ... Nature communications 12 (1), 3763, 2021 | 28 | 2021 |
| Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors J Duan, DD Shen, T Zhao, S Guo, X He, W Yin, P Xu, Y Ji, LN Chen, J Liu, ... Nature Communications 13 (1), 1364, 2022 | 17 | 2022 |
| Hormone-and antibody-mediated activation of the thyrotropin receptor J Duan, P Xu, X Luan, Y Ji, X He, N Song, Q Yuan, Y Jin, X Cheng, ... Nature 609 (7928), 854-859, 2022 | 16 | 2022 |
| Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3 Z Shao, Y Tan, Q Shen, L Hou, B Yao, J Qin, P Xu, C Mao, LN Chen, ... Cell Discovery 8 (1), 44, 2022 | 12 | 2022 |
| Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody: mechanisms for the high infectivity, immune evasion and antibody drug discovery W Yin, Y Xu, P Xu, X Cao, C Wu, C Gu, X He, X Wang, S Huang, Q Yuan, ... bioRxiv, 2021.12. 27.474273, 2021 | 11 | 2021 |
| GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors S Huang, P Xu, DD Shen, IA Simon, C Mao, Y Tan, H Zhang, K Harpsøe, ... Molecular cell 82 (14), 2681-2695. e6, 2022 | 10 | 2022 |
| Structural identification of lysophosphatidylcholines as activating ligands for orphan receptor GPR119 P Xu, S Huang, S Guo, Y Yun, X Cheng, X He, P Cai, Y Lan, H Zhou, ... Nature Structural & Molecular Biology 29 (9), 863-870, 2022 | 8 | 2022 |
| Structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-HT1F–G protein complex S Huang, P Xu, Y Tan, C You, Y Zhang, Y Jiang, HE Xu Cell Research 31 (9), 1036–1038, 2021 | 8 | 2021 |
| Structural insights into the peptide selectivity and activation of human neuromedin U receptors C You, Y Zhang, P Xu, S Huang, W Yin, H Eric Xu, Y Jiang Nature Communications 13 (1), 2045, 2022 | 5 | 2022 |
| Structural insights into the ligand binding and Gi coupling of serotonin receptor 5-HT5A Y Tan, P Xu, S Huang, G Yang, F Zhou, X He, H Ma, HE Xu, Y Jiang Cell Discovery 8 (1), 50, 2022 | 3 | 2022 |
| Structural basis for the therapeutic advantage of dual and triple agonists at the human GIP, GLP-1 or GCG receptors F Zhao, Q Zhou, Z Cong, K Hang, X Zou, C Zhang, Y Chen, A Dai, A Liang, ... bioRxiv, 2021.07. 29.454286, 2021 | 3 | 2021 |
| Universal mechanism of hormone and allosteric agonist mediated activation of glycoprotein hormone receptors as revealed by structures of follicle stimulating hormone receptor J Duan, P Xu, H Zhang, X Luan, J Yang, C Mao, DD Shen, Y Ji, X He, ... BioRxiv, 2022.08. 01.502312, 2022 | 2 | 2022 |
