Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor β signaling S Weissmueller, E Manchado, M Saborowski, JP Morris, E Wagenblast, ... Cell 157 (2), 382-394, 2014 | 525 | 2014 |
Asparagine bioavailability governs metastasis in a model of breast cancer SRV Knott, E Wagenblast, S Khan, SY Kim, M Soto, M Wagner, ... Nature 554 (7692), 378-381, 2018 | 470 | 2018 |
A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis E Wagenblast, M Soto, S Gutiérrez-Ángel, CA Hartl, AL Gable, AR Maceli, ... Nature 520 (7547), 358-362, 2015 | 434 | 2015 |
A computational algorithm to predict shRNA potency SRV Knott, AR Maceli, N Erard, K Chang, K Marran, X Zhou, A Gordon, ... Molecular cell 56 (6), 796-807, 2014 | 119 | 2014 |
Integrated stress response activity marks stem cells in normal hematopoiesis and leukemia P van Galen, N Mbong, A Kreso, EM Schoof, E Wagenblast, SWK Ng, ... Cell reports 25 (5), 1109-1117. e5, 2018 | 116 | 2018 |
Sphingolipid modulation activates proteostasis programs to govern human hematopoietic stem cell self-renewal SZ Xie, L Garcia-Prat, V Voisin, R Ferrari, OI Gan, E Wagenblast, ... Cell stem cell 25 (5), 639-653. e7, 2019 | 95 | 2019 |
TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate L García-Prat, KB Kaufmann, F Schneiter, V Voisin, A Murison, J Chen, ... Cell stem cell 28 (10), 1838-1850. e10, 2021 | 90 | 2021 |
Mapping the cellular origin and early evolution of leukemia in Down syndrome E Wagenblast, J Araújo, OI Gan, SK Cutting, A Murison, G Krivdova, ... Science 373 (6551), eabf6202, 2021 | 53 | 2021 |
Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation SZ Xie, KB Kaufmann, W Wang, M Chan-Seng-Yue, OI Gan, E Laurenti, ... Blood cancer discovery 2 (1), 32-53, 2021 | 40 | 2021 |
Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells E Wagenblast, M Azkanaz, SA Smith, L Shakib, JL McLeod, G Krivdova, ... Nature communications 10 (1), 1-11, 2019 | 34 | 2019 |
A stemness screen reveals C3orf54/INKA1 as a promoter of human leukemia stem cell latency KB Kaufmann, L Garcia-Prat, Q Liu, SWK Ng, SI Takayanagi, A Mitchell, ... Blood, The Journal of the American Society of Hematology 133 (20), 2198-2211, 2019 | 28 | 2019 |
Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo O Sonzogni, J Haynes, LA Seifried, YM Kamel, K Huang, MD BeGora, ... PLoS biology 16 (6), e2004049, 2018 | 26 | 2018 |
Characterization of universal features of partially methylated domains across tissues and species BE Decato, J Qu, X Ji, E Wagenblast, SRV Knott, GJ Hannon, AD Smith Epigenetics & chromatin 13, 1-14, 2020 | 23 | 2020 |
Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t (8; 21) AML G Krivdova, V Voisin, EM Schoof, SA Marhon, A Murison, JL McLeod, ... Cell reports 38 (10), 2022 | 8 | 2022 |
A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome H Boutzen, SA Madani Tonekaboni, M Chan-Seng-Yue, A Murison, ... Leukemia 36 (11), 2690-2704, 2022 | 7 | 2022 |
A hematopoietic stem cell subset that retains memory of prior inflammatory stress accumulates in aging and clonal hematopoiesis AG Zeng, MS Nagree, NA Jakobsen, S Shah, A Murison, J Cheong, I Lim, ... | 5 | 2023 |