Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13120* | 2021 |
Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway BD Manning, AR Tee, MN Logsdon, J Blenis, LC Cantley Molecular cell 10 (1), 151-162, 2002 | 1930 | 2002 |
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb AR Tee, BD Manning, PP Roux, LC Cantley, J Blenis Current biology 13 (15), 1259-1268, 2003 | 1505 | 2003 |
mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E DC Fingar, CJ Richardson, AR Tee, L Cheatham, C Tsou, J Blenis Molecular and cellular biology, 2004 | 1131 | 2004 |
Tuberous sclerosis complex-1 and-2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling AR Tee, DC Fingar, BD Manning, DJ Kwiatkowski, LC Cantley, J Blenis Proceedings of the National Academy of Sciences 99 (21), 13571-13576, 2002 | 1025 | 2002 |
Hypoxia-inducible factor 1α is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif SC Land, AR Tee Journal of Biological Chemistry 282 (28), 20534-20543, 2007 | 612 | 2007 |
The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses EM Smith, SG Finn, AR Tee, GJ Browne, CG Proud Journal of Biological Chemistry 280 (19), 18717-18727, 2005 | 479 | 2005 |
mTOR and autophagy: a dynamic relationship governed by nutrients and energy EA Dunlop, AR Tee Seminars in cell & developmental biology 36, 121-129, 2014 | 470 | 2014 |
Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning SL Cai, AR Tee, JD Short, JM Bergeron, J Kim, J Shen, R Guo, ... The Journal of cell biology 173 (2), 279-289, 2006 | 437 | 2006 |
mTOR, translational control and human disease AR Tee, J Blenis Seminars in cell & developmental biology 16 (1), 29-37, 2005 | 431 | 2005 |
Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability. A Beugnet, AR Tee, PM Taylor, CG Proud Biochemical Journal 372 (Pt 2), 555, 2003 | 375 | 2003 |
mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3 KM Dodd, J Yang, MH Shen, JR Sampson, AR Tee Oncogene 34 (17), 2239-2250, 2015 | 345 | 2015 |
Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms EA Dunlop, AR Tee Cellular signalling 21 (6), 827-835, 2009 | 330 | 2009 |
Inactivation of the tuberous sclerosis complex-1 and-2 gene products occurs by phosphoinositide 3-kinase/Akt-dependent and-independent phosphorylation of tuberin AR Tee, R Anjum, J Blenis Journal of Biological Chemistry 278 (39), 37288-37296, 2003 | 284 | 2003 |
A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS J Zhang, J Kim, A Alexander, S Cai, DN Tripathi, R Dere, AR Tee, ... Nature cell biology 15 (10), 1186-1196, 2013 | 281 | 2013 |
mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action GA Soliman, HA Acosta-Jaquez, EA Dunlop, B Ekim, NE Maj, AR Tee, ... Journal of Biological Chemistry 285 (11), 7866-7879, 2010 | 277 | 2010 |
Leucine and mTORC1: a complex relationship KM Dodd, AR Tee American Journal of Physiology-Endocrinology and Metabolism, 2012 | 272 | 2012 |
Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2–mediated suppression of mTORC1 DN Tripathi, R Chowdhury, LJ Trudel, AR Tee, RS Slack, CL Walker, ... Proceedings of the National Academy of Sciences 110 (32), E2950-E2957, 2013 | 246 | 2013 |
ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding EA Dunlop, DK Hunt, HA Acosta-Jaquez, DC Fingar, AR Tee Autophagy 7 (7), 737-747, 2011 | 241 | 2011 |
The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites TP Herbert, AR Tee, CG Proud Journal of Biological Chemistry 277 (13), 11591-11596, 2002 | 229 | 2002 |