关注
Andrew Tee
Andrew Tee
Professor of Cancer and Genetics
在 cardiff.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13120*2021
Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway
BD Manning, AR Tee, MN Logsdon, J Blenis, LC Cantley
Molecular cell 10 (1), 151-162, 2002
19302002
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
AR Tee, BD Manning, PP Roux, LC Cantley, J Blenis
Current biology 13 (15), 1259-1268, 2003
15052003
mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E
DC Fingar, CJ Richardson, AR Tee, L Cheatham, C Tsou, J Blenis
Molecular and cellular biology, 2004
11312004
Tuberous sclerosis complex-1 and-2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling
AR Tee, DC Fingar, BD Manning, DJ Kwiatkowski, LC Cantley, J Blenis
Proceedings of the National Academy of Sciences 99 (21), 13571-13576, 2002
10252002
Hypoxia-inducible factor 1α is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif
SC Land, AR Tee
Journal of Biological Chemistry 282 (28), 20534-20543, 2007
6122007
The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses
EM Smith, SG Finn, AR Tee, GJ Browne, CG Proud
Journal of Biological Chemistry 280 (19), 18717-18727, 2005
4792005
mTOR and autophagy: a dynamic relationship governed by nutrients and energy
EA Dunlop, AR Tee
Seminars in cell & developmental biology 36, 121-129, 2014
4702014
Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning
SL Cai, AR Tee, JD Short, JM Bergeron, J Kim, J Shen, R Guo, ...
The Journal of cell biology 173 (2), 279-289, 2006
4372006
mTOR, translational control and human disease
AR Tee, J Blenis
Seminars in cell & developmental biology 16 (1), 29-37, 2005
4312005
Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability.
A Beugnet, AR Tee, PM Taylor, CG Proud
Biochemical Journal 372 (Pt 2), 555, 2003
3752003
mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3
KM Dodd, J Yang, MH Shen, JR Sampson, AR Tee
Oncogene 34 (17), 2239-2250, 2015
3452015
Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms
EA Dunlop, AR Tee
Cellular signalling 21 (6), 827-835, 2009
3302009
Inactivation of the tuberous sclerosis complex-1 and-2 gene products occurs by phosphoinositide 3-kinase/Akt-dependent and-independent phosphorylation of tuberin
AR Tee, R Anjum, J Blenis
Journal of Biological Chemistry 278 (39), 37288-37296, 2003
2842003
A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS
J Zhang, J Kim, A Alexander, S Cai, DN Tripathi, R Dere, AR Tee, ...
Nature cell biology 15 (10), 1186-1196, 2013
2812013
mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action
GA Soliman, HA Acosta-Jaquez, EA Dunlop, B Ekim, NE Maj, AR Tee, ...
Journal of Biological Chemistry 285 (11), 7866-7879, 2010
2772010
Leucine and mTORC1: a complex relationship
KM Dodd, AR Tee
American Journal of Physiology-Endocrinology and Metabolism, 2012
2722012
Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2–mediated suppression of mTORC1
DN Tripathi, R Chowdhury, LJ Trudel, AR Tee, RS Slack, CL Walker, ...
Proceedings of the National Academy of Sciences 110 (32), E2950-E2957, 2013
2462013
ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding
EA Dunlop, DK Hunt, HA Acosta-Jaquez, DC Fingar, AR Tee
Autophagy 7 (7), 737-747, 2011
2412011
The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites
TP Herbert, AR Tee, CG Proud
Journal of Biological Chemistry 277 (13), 11591-11596, 2002
2292002
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