| Mutations in U6 snRNA that alter splice site specificity: implications for the active site CF Lesser, C Guthrie Science 262 (5142), 1982-1989, 1993 | 372 | 1993 |
| Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes A Sandstrom, PS Mitchell, L Goers, EW Mu, CF Lesser, RE Vance Science 364 (6435), eaau1330, 2019 | 339 | 2019 |
| Mutational analysis of pre-mRNA splicing in Saccharomyces cerevisiae using a sensitive new reporter gene, CUP1. CF Lesser, C Guthrie Genetics 133 (4), 851-863, 1993 | 207 | 1993 |
| The phi 80 and P22 attachment sites. Primary structure and interaction with Escherichia coli integration host factor. JM Leong, S Nunes-Düby, CF Lesser, P Youderian, MM Susskind, ... Journal of Biological Chemistry 260 (7), 4468-4477, 1985 | 201 | 1985 |
| Expression of microbial virulence proteins in Saccharomyces cerevisiae models mammalian infection CF Lesser, SI Miller The EMBO journal, 2001 | 133 | 2001 |
| Identification and Characterization of ZapC, a Stabilizer of the FtsZ Ring in Escherichia coli JM Durand-Heredia, HH Yu, S De Carlo, CF Lesser, A Janakiraman Journal of bacteriology 193 (6), 1405-1413, 2011 | 127 | 2011 |
| GEF-H1 mediated control of NOD1 dependent NF-κB activation by Shigella effectors A Fukazawa, C Alonso, K Kurachi, S Gupta, CF Lesser, BA McCormick, ... PLoS Pathog 4 (11), e1000228, 2008 | 127 | 2008 |
| Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions M Kutsch, L Sistemich, CF Lesser, MB Goldberg, C Herrmann, J Coers The EMBO journal 39 (13), e104926, 2020 | 117 | 2020 |
| Yeast functional genomic screens lead to identification of a role for a bacterial effector in innate immunity regulation RW Kramer, NL Slagowski, NA Eze, KS Giddings, MF Morrison, ... PLoS Pathog 3 (2), e21, 2007 | 117 | 2007 |
| The yeast Saccharomyces cerevisiae: a versatile model system for the identification and characterization of bacterial virulence proteins KA Siggers, CF Lesser Cell host & microbe 4 (1), 8-15, 2008 | 113 | 2008 |
| The type III secretion system apparatus determines the intracellular niche of bacterial pathogens J Du, AZ Reeves, JA Klein, DJ Twedt, LA Knodler, CF Lesser Proceedings of the National Academy of Sciences 113 (17), 4794-4799, 2016 | 105 | 2016 |
| Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility AS Piro, D Hernandez, S Luoma, EM Feeley, R Finethy, A Yirga, ... MBio 8 (6), 10.1128/mbio. 01979-17, 2017 | 101 | 2017 |
| Disseminated sporotrichosis associated with treatment with immunosuppressants and tumor necrosis factor-α antagonists GS Gottlieb, CF Lesser, KK Holmes, A Wald Clinical Infectious Diseases 37 (6), 838-840, 2003 | 92 | 2003 |
| The C-Terminal Tail of Yersinia pseudotuberculosis YopM Is Critical for Interacting with RSK1 and for Virulence MW McCoy, ML Marré, CF Lesser, J Mecsas Infection and immunity 78 (6), 2584-2598, 2010 | 88 | 2010 |
| A functional genomic yeast screen to identify pathogenic bacterial proteins NL Slagowski, RW Kramer, MF Morrison, J LaBaer, CF Lesser PLoS Pathog 4 (1), e9, 2008 | 87 | 2008 |
| Structural and regulatory divergence among site-specific recombination genes of lambdoid phage JM Leong, SE Nunes-Düby, AB Oser, CF Lesser, P Youderian, ... Journal of molecular biology 189 (4), 603-616, 1986 | 84 | 1986 |
| The essential role of the CopN protein in Chlamydia pneumoniae intracellular growth J Huang, CF Lesser, S Lory Nature 456 (7218), 112-115, 2008 | 83 | 2008 |
| NAIP–NLRC4-deficient mice are susceptible to shigellosis PS Mitchell, JL Roncaioli, EA Turcotte, L Goers, RA Chavez, AY Lee, ... Elife 9, e59022, 2020 | 80 | 2020 |
| Requirement for Formin-Induced Actin Polymerization during Spread of Shigella flexneri JE Heindl, I Saran, C Yi, CF Lesser, MB Goldberg Infection and immunity 78 (1), 193-203, 2010 | 73 | 2010 |
| Sequences beyond the cleavage site influence signal peptide function. DW Andrews, E Perara, C Lesser, VR Lingappa Journal of Biological Chemistry 263 (30), 15791-15798, 1988 | 73 | 1988 |
