Whole-brain activity mapping onto a zebrafish brain atlas O Randlett, CL Wee, EA Naumann, O Nnaemeka, D Schoppik, ... Nature methods 12 (11), 1039-1046, 2015 | 474 | 2015 |
Applications of machine learning to diagnosis and treatment of neurodegenerative diseases MA Myszczynska, PN Ojamies, AMB Lacoste, D Neil, A Saffari, R Mead, ... Nature reviews neurology 16 (8), 440-456, 2020 | 450 | 2020 |
Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis N Bakkar, T Kovalik, I Lorenzini, S Spangler, A Lacoste, K Sponaugle, ... Acta neuropathologica 135, 227-247, 2018 | 176 | 2018 |
A convergent and essential interneuron pathway for Mauthner-cell-mediated escapes AMB Lacoste, D Schoppik, DN Robson, M Haesemeyer, R Portugues, ... Current Biology 25 (11), 1526-1534, 2015 | 111 | 2015 |
Zebrafish oxytocin neurons drive nocifensive behavior via brainstem premotor targets CL Wee, M Nikitchenko, WC Wang, SJ Luks-Morgan, E Song, JA Gagnon, ... Nature neuroscience 22 (9), 1477-1492, 2019 | 62 | 2019 |
Interpretable graph convolutional neural networks for inference on noisy knowledge graphs D Neil, J Briody, A Lacoste, A Sim, P Creed, A Saffari arXiv preprint arXiv:1812.00279, 2018 | 42 | 2018 |
Preclinical validation of therapeutic targets predicted by tensor factorization on heterogeneous graphs S Paliwal, A de Giorgio, D Neil, JB Michel, AMB Lacoste Scientific reports 10 (1), 18250, 2020 | 39 | 2020 |
Expert-augmented computational drug repurposing identified baricitinib as a treatment for COVID-19 DP Smith, O Oechsle, MJ Rawling, E Savory, AMB Lacoste, ... Frontiers in pharmacology 12, 709856, 2021 | 37 | 2021 |
Repurposing drugs to treat l-DOPA-induced dyskinesia in Parkinson's disease TH Johnston, AMB Lacoste, NP Visanji, AE Lang, SH Fox, JM Brotchie Neuropharmacology 147, 11-27, 2019 | 33 | 2019 |
Identifying drugs with disease‐modifying potential in Parkinson's disease using artificial intelligence and pharmacoepidemiology LC Maclagan, NP Visanji, Y Cheng, M Tadrous, AMB Lacoste, LV Kalia, ... Pharmacoepidemiology and drug safety 29 (8), 864-872, 2020 | 29 | 2020 |
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans KS Chen, K Menezes, JB Rodgers, DM O’Hara, N Tran, K Fujisawa, ... Molecular Neurodegeneration 16, 1-25, 2021 | 17 | 2021 |
Identification of pharmacodynamic biomarker hypotheses through literature analysis with IBM Watson S Hatz, S Spangler, A Bender, M Studham, P Haselmayer, AMB Lacoste, ... PloS one 14 (4), e0214619, 2019 | 17 | 2019 |
Graph neutral networks with attention P Creed, SIM Aaron, A Alamdari, J Briody, D Neil, A Lacoste US Patent App. 17/041,625, 2021 | 15 | 2021 |
Using artificial intelligence to identify anti‐hypertensives as possible disease modifying agents in Parkinson's disease NP Visanji, P Madan, AMB Lacoste, I Buleje, Y Han, S Spangler, LV Kalia, ... Pharmacoepidemiology and Drug Safety 30 (2), 201-209, 2021 | 14 | 2021 |
Rate of pathogenic germline variants in patients with lung cancer S Sorscher, J LoPiccolo, B Heald, E Chen, SL Bristow, ST Michalski, ... JCO Precision Oncology 7, e2300190, 2023 | 11 | 2023 |
Machine learning for ranking candidate subjects based on a training set AM Lacoste, WS Spangler US Patent 11,182,692, 2021 | 4 | 2021 |
Classification of cardiovascular proteins involved in coronary atherosclerosis and heart failure using Watson’s cognitive computing technology CT Ruff, A Lacoste, F Nordio, CL Fanola, MG Silverman, E Argentinis, ... Circulation 136 (suppl_1), A16678-A16678, 2017 | 4 | 2017 |
Using artificial intelligence to identify drugs for repurposing to treat l-DOPA-induced dyskinesia TH Johnston, AMB Lacoste, P Ravenscroft, J Su, S Tamadon, M Seifi, ... Neuropharmacology 248, 109880, 2024 | 1 | 2024 |
Computation of longitudinal phenotypes in 466 individuals with a developmental and epileptic encephalopathy enables clinical trial readiness E Brimble, J Kim, RL Martin, D McKnight, AMB Lacoste medRxiv, 2023.03. 02.23286645, 2023 | 1 | 2023 |
Ranking biological entity pairs by evidence level DL Neil, AMB LaCoste, A DeGiorgio, I Churcher, RD Sutherland, Y Gao US Patent App. 17/625,113, 2022 | 1 | 2022 |