| TREM2 regulates microglial cholesterol metabolism upon chronic phagocytic challenge AA Nugent, K Lin, B Van Lengerich, S Lianoglou, L Przybyla, SS Davis, ... Neuron 105 (5), 837-854. e9, 2020 | 443 | 2020 |
| A core transcriptional network for early mesoderm development in Drosophila melanogaster T Sandmann, C Girardot, M Brehme, W Tongprasit, V Stolc, EEM Furlong Genes & development 21 (4), 436-449, 2007 | 359 | 2007 |
| Patients with proneural glioblastoma may derive overall survival benefit from the addition of bevacizumab to first-line radiotherapy and temozolomide: retrospective analysis of … T Sandmann, R Bourgon, J Garcia, C Li, T Cloughesy, OL Chinot, W Wick, ... Journal of clinical oncology 33 (25), 2735-2744, 2015 | 325 | 2015 |
| Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells O Voloshanenko, G Erdmann, TD Dubash, I Augustin, M Metzig, G Moffa, ... Nature communications 4 (1), 2610, 2013 | 278 | 2013 |
| A temporal map of transcription factor activity: mef2 directly regulates target genes at all stages of muscle development T Sandmann, LJ Jensen, JS Jakobsen, MM Karzynski, MP Eichenlaub, ... Developmental cell 10 (6), 797-807, 2006 | 272 | 2006 |
| Mapping of signaling networks through synthetic genetic interaction analysis by RNAi T Horn, T Sandmann, B Fischer, E Axelsson, W Huber, M Boutros Nature methods 8 (4), 341-346, 2011 | 211 | 2011 |
| Alzheimer’s-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia BJ Andreone, L Przybyla, C Llapashtica, A Rana, SS Davis, ... Nature Neuroscience 23 (8), 927-938, 2020 | 169 | 2020 |
| Anti-CD22 and anti-CD79B antibody drug conjugates are active in different molecular diffuse large B-cell lymphoma subtypes M Pfeifer, B Zheng, T Erdmann, H Koeppen, R McCord, M Grau, A Staiger, ... Leukemia 29 (7), 1578-1586, 2015 | 163 | 2015 |
| Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice JC Ullman, A Arguello, JA Getz, A Bhalla, CS Mahon, J Wang, T Giese, ... Science Translational Medicine 12 (545), eaay1163, 2020 | 149 | 2020 |
| The head-regeneration transcriptome of the planarian Schmidtea mediterranea T Sandmann, MC Vogg, S Owlarn, M Boutros, K Bartscherer Genome biology 12, 1-19, 2011 | 144 | 2011 |
| Randomized, double-blind, placebo-controlled, multicenter phase ii study of onartuzumab plus bevacizumab versus placebo plus bevacizumab in patients with recurrent glioblastoma … T Cloughesy, G Finocchiaro, C Belda-Iniesta, L Recht, AA Brandes, ... Journal of clinical oncology 35 (3), 343-351, 2017 | 137 | 2017 |
| Hypoxia and oxygenation induce a metabolic switch between pentose phosphate pathway and glycolysis in glioma stem-like cells A Kathagen, A Schulte, G Balcke, HS Phillips, T Martens, J Matschke, ... Acta neuropathologica 126, 763-780, 2013 | 132 | 2013 |
| ChIP-on-chip protocol for genome-wide analysis of transcription factor binding in Drosophila melanogaster embryos T Sandmann, JS Jakobsen, EEM Furlong Nature protocols 1 (6), 2839-2855, 2006 | 115 | 2006 |
| Mondo/ChREBP-Mlx-Regulated Transcriptional Network Is Essential for Dietary Sugar Tolerance in Drosophila E Havula, M Teesalu, T Hyötyläinen, H Seppälä, K Hasygar, P Auvinen, ... PLoS genetics 9 (4), e1003438, 2013 | 112 | 2013 |
| A map of directional genetic interactions in a metazoan cell B Fischer, T Sandmann, T Horn, M Billmann, V Chaudhary, W Huber, ... Elife 4, e05464, 2015 | 102 | 2015 |
| Design and evaluation of genome-wide libraries for RNA interference screens T Horn, T Sandmann, M Boutros Genome biology 11, 1-12, 2010 | 100 | 2010 |
| Temporal ChIP-on-chip reveals Biniou as a universal regulator of the visceral muscle transcriptional network JS Jakobsen, M Braun, J Astorga, EH Gustafson, T Sandmann, ... Genes & development 21 (19), 2448-2460, 2007 | 97 | 2007 |
| Mondo-Mlx mediates organismal sugar sensing through the Gli-similar transcription factor sugarbabe J Mattila, E Havula, E Suominen, M Teesalu, I Surakka, R Hynynen, ... Cell reports 13 (2), 350-364, 2015 | 89 | 2015 |
| Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter X Qu, T Sandmann, H Frierson, L Fu, E Fuentes, K Walter, K Okrah, ... Oncogene 35 (50), 6403-6415, 2016 | 77 | 2016 |
| A cysteine-clamp gene drives embryo polarity in the midge Chironomus J Klomp, D Athy, CW Kwan, NI Bloch, T Sandmann, S Lemke, ... Science 348 (6238), 1040-1042, 2015 | 48 | 2015 |
Richard BourgonVice President of Computational Science, Freenome在 freenome.com 的电子邮件经过验证
