Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease AT Argaw, L Asp, J Zhang, K Navrazhina, T Pham, JN Mariani, S Mahase, ... The Journal of clinical investigation 122 (7), 2454-2468, 2012 | 694 | 2012 |
Astrocytic tight junctions control inflammatory CNS lesion pathogenesis S Horng, A Therattil, S Moyon, A Gordon, K Kim, AT Argaw, Y Hara, ... The Journal of clinical investigation 127 (8), 3136-3151, 2017 | 205 | 2017 |
Astrocytic TYMP and VEGFA drive blood–brain barrier opening in inflammatory central nervous system lesions C Chapouly, A Tadesse Argaw, S Horng, K Castro, J Zhang, L Asp, H Loo, ... Brain 138 (6), 1548-1567, 2015 | 171 | 2015 |
Adolescent C57BL/6J (but not DBA/2J) mice consume greater amounts of limited‐access ethanol compared to adults and display continued elevated ethanol intake into adulthood EM Moore, JN Mariani, DN Linsenbardt, LC Melón, SL Boehm Alcoholism: Clinical and Experimental Research 34 (4), 734-742, 2010 | 89 | 2010 |
Human ESC-derived chimeric mouse models of Huntington’s disease reveal cell-intrinsic defects in glial progenitor cell differentiation M Osipovitch, AA Martinez, JN Mariani, A Cornwell, S Dhaliwal, L Zou, ... Cell Stem Cell 24 (1), 107-122. e7, 2019 | 84 | 2019 |
Impaired Hedgehog signalling-induced endothelial dysfunction is sufficient to induce neuropathy: implication in diabetes C Chapouly, Q Yao, S Vandierdonck, F Larrieu-Lahargue, JN Mariani, ... Cardiovascular research 109 (2), 217-227, 2016 | 68 | 2016 |
The transcriptional activator Krüppel-like factor-6 is required for CNS myelination BM Laitman, L Asp, JN Mariani, J Zhang, J Liu, S Sawai, C Chapouly, ... PLoS biology 14 (5), e1002467, 2016 | 46 | 2016 |
Human glial progenitor cells effectively remyelinate the demyelinated adult brain MS Windrem, SJ Schanz, L Zou, D Chandler-Militello, NJ Kuypers, ... Cell reports 31 (7), 2020 | 35 | 2020 |
Cell-intrinsic glial pathology is conserved across human and murine models of Huntington’s disease A Benraiss, JN Mariani, M Osipovitch, A Cornwell, MS Windrem, ... Cell reports 36 (1), 2021 | 34 | 2021 |
Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination DJ Dutta, A Zameer, JN Mariani, J Zhang, L Asp, J Huynh, S Mahase, ... Development 141 (12), 2414-2428, 2014 | 31 | 2014 |
Promoting myelin repair and return of function in multiple sclerosis J Zhang, EG Kramer, L Asp, DJ Dutta, K Navrazhina, T Pham, JN Mariani, ... FEBS letters 585 (23), 3813-3820, 2011 | 26 | 2011 |
A TCF7L2-responsive suppression of both homeostatic and compensatory remyelination in Huntington disease mice A Benraiss, JN Mariani, A Tate, PM Madsen, KM Clark, KA Welle, R Solly, ... Cell Reports 40 (9), 2022 | 20 | 2022 |
Human glial chimeric mice to define the role of glial pathology in human disease JN Mariani, L Zou, SA Goldman Oligodendrocytes: Methods and Protocols, 311-331, 2019 | 19 | 2019 |
Young glial progenitor cells competitively replace aged and diseased human glia in the adult chimeric mouse brain R Vieira, JN Mariani, NPT Huynh, HJT Stephensen, R Solly, A Tate, ... Nature Biotechnology, 1-12, 2023 | 12 | 2023 |
Glial progenitor cell-based repair of the dysmyelinated brain: Progression to the clinic SA Goldman, JN Mariani, PM Madsen Seminars in Cell & Developmental Biology 116, 62-70, 2021 | 11 | 2021 |
Karyopherin alpha proteins regulate oligodendrocyte differentiation BM Laitman, JN Mariani, C Zhang, S Sawai, GR John Plos one 12 (1), e0170477, 2017 | 9 | 2017 |
CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance M Takasugi, N Ohtani, K Takemura, S Emmrich, FT Zakusilo, Y Yoshida, ... Cell Reports 42 (9), 2023 | 5 | 2023 |
Glial progenitor cells of the adult human white and grey matter are contextually distinct MJ Osorio, JN Mariani, L Zou, SJ Schanz, K Heffernan, A Cornwell, ... Glia, 2022 | 3 | 2022 |
Correction: Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination (doi: 10.1242/dev. 106492) DJ Dutta, A Zameer, JN Mariani, J Zhang, L Asp, J Huynh, S Mahase, ... Development 145 (13), dev168708, 2018 | 2 | 2018 |
Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease A Argaw, L Asp, J Zhang, K Navrazhina, T Pham, J Mariani, S Mahase, ... Multiple Sclerosis Journal 19 (11), 134-134, 2013 | 2 | 2013 |