The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption SA Anderson, CP Nizzi, YI Chang, KM Deck, PJ Schmidt, B Galy, ... Cell metabolism 17 (2), 282-290, 2013 | 230 | 2013 |
Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo X Gao, KD Johnson, YI Chang, ME Boyer, CN Dewey, J Zhang, ... Journal of Experimental Medicine 210 (13), 2833-2842, 2013 | 172 | 2013 |
Structure and function of a custom anticancer peptide, CB1a JM Wu, PS Jan, HC Yu, HY Haung, HJ Fang, YI Chang, JW Cheng, ... Peptides 30 (5), 839-848, 2009 | 92 | 2009 |
Cis-regulatory mechanisms governing stem and progenitor cell transitions KD Johnson, G Kong, X Gao, YI Chang, KJ Hewitt, R Sanalkumar, ... Science Advances 1 (8), 2015 | 72 | 2015 |
NrasG12D/+ promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions J Wang, G Kong, Y Liu, J Du, YI Chang, SR Tey, X Zhang, EA Ranheim, ... Blood, The Journal of the American Society of Hematology 121 (26), 5203-5207, 2013 | 62 | 2013 |
Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm G Kong, M Wunderlich, D Yang, EA Ranheim, KH Young, J Wang, ... The Journal of clinical investigation 124 (6), 2762-2773, 2014 | 56 | 2014 |
Mechanism governing a stem cell-generating cis-regulatory element R Sanalkumar, KD Johnson, X Gao, ME Boyer, YI Chang, KJ Hewitt, ... Proceedings of the National Academy of Sciences 111 (12), E1091-E1100, 2014 | 53 | 2014 |
PICK1, an anchoring protein that specifically targets protein kinase Cα to mitochondria selectively upon serum stimulation in NIH 3T3 cells WL Wang, SF Yeh, YI Chang, SF Hsiao, WN Lian, CH Lin, CYF Huang, ... Journal of Biological Chemistry 278 (39), 37705-37712, 2003 | 52 | 2003 |
Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis G Kong, YI Chang, A Damnernsawad, X You, J Du, EA Ranheim, W Lee, ... Leukemia 30 (7), 1542-1551, 2016 | 46 | 2016 |
Loss of Dnmt3a and endogenous Kras G12D/+ cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis YI Chang, X You, G Kong, EA Ranheim, J Wang, J Du, Y Liu, Y Zhou, ... Leukemia 29 (9), 1847-1856, 2015 | 46 | 2015 |
Notch1 gene mutations target KRAS G12D-expressing CD8+ cells and contribute to their leukemogenic transformation G Kong, J Du, Y Liu, B Meline, YI Chang, EA Ranheim, J Wang, J Zhang Journal of Biological Chemistry 288 (25), 18219-18227, 2013 | 36 | 2013 |
Protein-arginine methyltransferase 1 suppresses megakaryocytic differentiation via modulation of the p38 MAPK pathway in K562 cells YI Chang, WK Hua, CL Yao, SM Hwang, YC Hung, CJ Kuan, JS Leou, ... Journal of Biological Chemistry 285 (27), 20595-20606, 2010 | 36 | 2010 |
p53 −/− synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia J Zhang, G Kong, A Rajagopalan, L Lu, J Song, M Hussaini, X Zhang, ... Blood, The Journal of the American Society of Hematology 129 (3), 358-370, 2017 | 35 | 2017 |
Identification of the methylation preference region in heterogeneous nuclear ribonucleoprotein K by protein arginine methyltransferase 1 and its implication in regulating … YI Chang, SC Hsu, GY Chau, CYF Huang, JS Sung, WK Hua, WJ Lin Biochemical and biophysical research communications 404 (3), 865-869, 2011 | 29 | 2011 |
The ability of endogenous Nras oncogenes to initiate leukemia is codon-dependent G Kong, YI Chang, X You, EA Ranheim, Y Zhou, CE Burd, J Zhang Leukemia 30 (9), 1935-1938, 2016 | 27 | 2016 |
Protein arginine methyltransferase 1 interacts with and activates p38α to facilitate erythroid differentiation WK Hua, YI Chang, CL Yao, SM Hwang, CY Chang, WJ Lin PloS one 8 (3), e56715, 2013 | 19 | 2013 |
Downregulating Notch counteracts Kras G12D-induced ERK activation and oxidative phosphorylation in myeloproliferative neoplasm G Kong, X You, Z Wen, YI Chang, S Qian, EA Ranheim, C Letson, ... Leukemia 33 (3), 671-685, 2019 | 16 | 2019 |
Evaluation of allelic strength of human TET2 mutations and cooperation between Tet2 knockdown and oncogenic Nras mutation YI Chang, A Damnernsawad, LK Allen, D Yang, EA Ranheim, KH Young, ... British journal of haematology 166 (3), 461, 2014 | 16 | 2014 |
Loss of CD44 attenuates aberrant GM-CSF signaling in Kras G12D hematopoietic progenitor/precursor cells and prolongs the survival of diseased animals J Du, Y Liu, B Meline, G Kong, LX Tan, JC Lo, J Wang, E Ranheim, ... Leukemia 27 (3), 754-757, 2013 | 16 | 2013 |
Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation JL Chen, YH Ping, MJ Tseng, YI Chang, HC Lee, RH Hsieh, TS Yeh Scientific reports 7 (1), 1-15, 2017 | 12 | 2017 |