Hematopoietic Stem Cell Quiescence Maintained by p21cip1/waf1 T Cheng, N Rodrigues, H Shen, Y Yang, D Dombkowski, M Sykes, ... Science 287 (5459), 1804-1808, 2000 | 1649 | 2000 |
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a V Janzen, R Forkert, HE Fleming, Y Saito, MT Waring, DM Dombkowski, ... Nature 443 (7110), 421-426, 2006 | 1305 | 2006 |
Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size S Stier, Y Ko, R Forkert, C Lutz, T Neuhaus, E Grünewald, T Cheng, ... The Journal of experimental medicine 201 (11), 1781-1791, 2005 | 841 | 2005 |
COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas X Ren, W Wen, X Fan, W Hou, B Su, P Cai, J Li, Y Liu, F Tang, F Zhang, ... Cell 184 (7), 1895-1913. e19, 2021 | 737 | 2021 |
CCAAT/enhancer binding protein α is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors HS Radomska, CS Huettner, PU Zhang, TAO Cheng, DT Scadden, ... Molecular and cellular biology 18 (7), 4301-4314, 1998 | 671 | 1998 |
Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome S Stier, T Cheng, D Dombkowski, N Carlesso, DT Scadden Blood, The Journal of the American Society of Hematology 99 (7), 2369-2378, 2002 | 576 | 2002 |
Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavage JP Zhang, XL Li, GH Li, W Chen, C Arakaki, GD Botimer, D Baylink, ... Genome biology 18, 1-18, 2017 | 542 | 2017 |
Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection X Xie, Q Shi, P Wu, X Zhang, H Kambara, J Su, H Yu, SY Park, R Guo, ... Nature immunology 21 (9), 1119-1133, 2020 | 541 | 2020 |
Stem cell repopulation efficiency but not pool size is governed by p27kip1 T Cheng, N Rodrigues, D Dombkowski, S Stier, DT Scadden Nature medicine 6 (11), 1235-1240, 2000 | 427 | 2000 |
Gasdermin D exerts anti-inflammatory effects by promoting neutrophil death H Kambara, F Liu, X Zhang, P Liu, B Bajrami, Y Teng, L Zhao, S Zhou, ... Cell reports 22 (11), 2924-2936, 2018 | 387 | 2018 |
Tracing haematopoietic stem cell formation at single-cell resolution F Zhou, X Li, W Wang, P Zhu, J Zhou, W He, M Ding, F Xiong, X Zheng, ... Nature 533 (7604), 487-492, 2016 | 366 | 2016 |
Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis R Qi, H An, Y Yu, M Zhang, S Liu, H Xu, Z Guo, T Cheng, X Cao Cancer research 63 (23), 8323-8329, 2003 | 361 | 2003 |
In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C Y Yuan, H Shen, DS Franklin, DT Scadden, T Cheng Nature cell biology 6 (5), 436-442, 2004 | 354 | 2004 |
New paradigms on hematopoietic stem cell differentiation H Cheng, Z Zheng, T Cheng Protein & cell 11 (1), 34-44, 2020 | 310 | 2020 |
Identification of functional cooperative mutations of SETD2 in human acute leukemia X Zhu, F He, H Zeng, S Ling, A Chen, Y Wang, X Yan, W Wei, Y Pang, ... Nature genetics 46 (3), 287-293, 2014 | 290 | 2014 |
A novel open-porous magnesium scaffold with controllable microstructures and properties for bone regeneration M Cheng, T Wahafu, G Jiang, W Liu, Y Qiao, X Peng, T Cheng, X Zhang, ... Scientific reports 6 (1), 24134, 2016 | 268 | 2016 |
Temporal mapping of gene expression levels during the differentiation of individual primary hematopoietic cells T Cheng, H Shen, D Giokas, J Gere, DG Tenen, DT Scadden Proceedings of the National Academy of Sciences 93 (23), 13158-13163, 1996 | 228 | 1996 |
The Wilms tumor suppressor WT1 directs stage‐specific quiescence and differentiation of human hematopoietic progenitor cells LW Ellisen, N Carlesso, T Cheng, DT Scadden, DA Haber The EMBO journal, 2001 | 226 | 2001 |
Efficiency of protein transduction is cell type-dependent and is enhanced by dextran sulfate JC Mai, H Shen, SC Watkins, T Cheng, PD Robbins Journal of Biological Chemistry 277 (33), 30208-30218, 2002 | 211 | 2002 |
Combinatorial single-cell analyses of granulocyte-monocyte progenitor heterogeneity reveals an early uni-potent neutrophil progenitor I Kwok, E Becht, Y Xia, M Ng, YC Teh, L Tan, M Evrard, JLY Li, HTN Tran, ... Immunity 53 (2), 303-318. e5, 2020 | 207 | 2020 |