Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes D Chiabrando, F Vinchi, V Fiorito, S Mercurio, E Tolosano Frontiers in pharmacology 5, 61, 2014 | 418 | 2014 |
Heme scavenging and the other facets of hemopexin E Tolosano, S Fagoonee, N Morello, F Vinchi, V Fiorito Antioxidants & redox signaling 12 (2), 305-320, 2010 | 301 | 2010 |
The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation D Chiabrando, S Marro, S Mercurio, C Giorgi, S Petrillo, F Vinchi, V Fiorito, ... The Journal of clinical investigation 122 (12), 4569-4579, 2012 | 206 | 2012 |
The multifaceted role of heme in cancer V Fiorito, D Chiabrando, S Petrillo, F Bertino, E Tolosano Frontiers in oncology 9, 1540, 2020 | 108 | 2020 |
Heme accumulation in endothelial cells impairs angiogenesis by triggering paraptosis S Petrillo, D Chiabrando, T Genova, V Fiorito, G Ingoglia, F Vinchi, ... Cell Death & Differentiation 25 (3), 573-588, 2018 | 92 | 2018 |
Haemopexin affects iron distribution and ferritin expression in mouse brain N Morello, E Tonoli, F Logrand, V Fiorito, S Fagoonee, E Turco, L Silengo, ... Journal of cellular and molecular medicine 13 (10), 4192-4204, 2009 | 60 | 2009 |
Unraveling the role of heme in neurodegeneration D Chiabrando, V Fiorito, S Petrillo, E Tolosano Frontiers in neuroscience 12, 712, 2018 | 55 | 2018 |
Hypoxia controls Flvcr1 gene expression in Caco2 cells through HIF2α and ETS1 V Fiorito, F Neri, V Pala, L Silengo, S Oliviero, F Altruda, E Tolosano Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (4), 259-264, 2014 | 44 | 2014 |
The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation V Fiorito, AL Allocco, S Petrillo, E Gazzano, S Torretta, S Marchi, ... Cell reports 35 (11), 2021 | 41 | 2021 |
Crucial role of FLVCR1a in the maintenance of intestinal heme homeostasis V Fiorito, M Forni, L Silengo, F Altruda, E Tolosano Antioxidants & redox signaling 23 (18), 1410-1423, 2015 | 35 | 2015 |
Mitochondrial targeting in neurodegeneration: a heme perspective V Fiorito, D Chiabrando, E Tolosano Pharmaceuticals 11 (3), 87, 2018 | 32 | 2018 |
Haptoglobin and hemopexin in heme detoxification and iron recycling D Chiabrando, F Vinchi, V Fiorito, E Tolosano Acute Phase Proteins-Regulation and Functions of Acute Phase Proteins, 261-288, 2011 | 28 | 2011 |
Cell-specific regulation of Ferroportin transcription following experimentally-induced acute anemia in mice D Chiabrando, V Fiorito, S Marro, L Silengo, F Altruda, E Tolosano Blood Cells, Molecules, and Diseases 50 (1), 25-30, 2013 | 26 | 2013 |
Assessment of iron absorption in mice by ICP-MS measurements of 57Fe levels V Fiorito, S Geninatti Crich, L Silengo, F Altruda, S Aime, E Tolosano European journal of nutrition 51, 783-789, 2012 | 24 | 2012 |
Heme and sensory neuropathy: insights from novel mutations in the heme exporter feline leukemia virus subgroup C receptor 1 F Bertino, K Firestone, E Bellacchio, KE Jackson, A Asamoah, J Hersh, ... Pain 160 (12), 2766-2775, 2019 | 20 | 2019 |
Lack of plasma protein hemopexin results in increased duodenal iron uptake V Fiorito, S Geninatti Crich, L Silengo, S Aime, F Altruda, E Tolosano PLoS One 8 (6), e68146, 2013 | 18 | 2013 |
Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis S Petrillo, F De Giorgio, F Bertino, F Garello, V Bitonto, DL Longo, ... Angiogenesis 26 (3), 365-384, 2023 | 12 | 2023 |
Hemopexin and cancer V Fiorito, E Tolosano International journal of molecular sciences 23 (2), 997, 2022 | 12 | 2022 |
Investigating the connection between endogenous heme accumulation and COX2 activity in cancer cells F Destefanis, V Fiorito, F Altruda, E Tolosano Frontiers in Oncology 9, 162, 2019 | 12 | 2019 |
Inhibition of heme export and/or heme synthesis potentiates metformin anti-proliferative effect on cancer cell lines AL Allocco, F Bertino, S Petrillo, D Chiabrando, C Riganti, A Bardelli, ... Cancers 14 (5), 1230, 2022 | 9 | 2022 |