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Daniel Simon Brewer
Daniel Simon Brewer
Professor of Medical Bioinformatics and Genomics, Norwich Medical School, University of East Anglia
在 uea.ac.uk 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1797*2020
The evolutionary history of lethal metastatic prostate cancer
G Gundem, P Van Loo, B Kremeyer, LB Alexandrov, JMC Tubio, ...
Nature 520 (7547), 353-357, 2015
14652015
A census of amplified and overexpressed human cancer genes
T Santarius, J Shipley, D Brewer, MR Stratton, CS Cooper
Nature Reviews Cancer 10 (1), 59-64, 2010
7122010
Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue
CS Cooper, R Eeles, DC Wedge, P Van Loo, G Gundem, LB Alexandrov, ...
Nature genetics 47 (4), 367-372, 2015
4842015
Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
JMC Tubio, Y Li, YS Ju, I Martincorena, SL Cooke, M Tojo, G Gundem, ...
Science 345 (6196), 1251343, 2014
4472014
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer
YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ...
elife 3, e02935, 2014
4092014
The landscape of viral associations in human cancers
M Zapatka, I Borozan, DS Brewer, M Iskar, A Grundhoff, M Alawi, N Desai, ...
Nature genetics 52 (3), 320-330, 2020
3402020
Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer
AHM Reid, G Attard, L Ambroisine, G Fisher, G Kovacs, D Brewer, J Clark, ...
British journal of cancer 102 (4), 678-684, 2010
3222010
Mutational signatures of ionizing radiation in second malignancies
S Behjati, G Gundem, DC Wedge, ND Roberts, PS Tarpey, SL Cooke, ...
Nature communications 7 (1), 1-8, 2016
2672016
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets
DC Wedge, G Gundem, T Mitchell, DJ Woodcock, I Martincorena, M Ghori, ...
Nature genetics 50 (5), 682-692, 2018
2342018
Ranked prediction of p53 targets using hidden variable dynamic modeling
M Barenco, D Tomescu, D Brewer, R Callard, J Stark, M Hubank
Genome biology 7, 1-18, 2006
1872006
Time-and concentration-dependent changes in gene expression induced by benzo (a) pyrene in two human cell lines, MCF-7 and HepG2
SL Hockley, VM Arlt, D Brewer, I Giddings, DH Phillips
BMC genomics 7, 1-23, 2006
1392006
Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study
D Olmos, D Brewer, J Clark, DC Danila, C Parker, G Attard, M Fleisher, ...
The lancet oncology 13 (11), 1114-1124, 2012
1332012
Prognostic value of PTEN loss in men with conservatively managed localised prostate cancer
J Cuzick, ZH Yang, G Fisher, E Tikishvili, S Stone, JS Lanchbury, ...
British journal of cancer 108 (12), 2582-2589, 2013
1272013
AHR- and DNA-Damage-Mediated Gene Expression Responses Induced by Benzo(a)pyrene in Human Cell Lines
SL Hockley, VM Arlt, D Brewer, R Te Poele, P Workman, I Giddings, ...
Chemical research in toxicology 20 (12), 1797-1810, 2007
1142007
TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer
JF Knight, CJ Shepherd, S Rizzo, D Brewer, S Jhavar, AR Dodson, ...
British journal of cancer 99 (11), 1849-1858, 2008
972008
Fitting ordinary differential equations to short time course data
D Brewer, M Barenco, R Callard, M Hubank, J Stark
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2008
892008
Detection of TMPRSS2-ERG translocations in human prostate cancer by expression profiling using GeneChip Human Exon 1.0 ST arrays
S Jhavar, A Reid, J Clark, Z Kote-Jarai, T Christmas, A Thompson, ...
The Journal of Molecular Diagnostics 10 (1), 50-57, 2008
842008
Integration of ERG gene mapping and gene‐expression profiling identifies distinct categories of human prostate cancer
S Jhavar, D Brewer, S Edwards, Z Kote‐Jarai, G Attard, J Clark, P Flohr, ...
BJU international 103 (9), 1256-1269, 2009
752009
Expression profiling of CD133+ and CD133—epithelial cells from human prostate
CJ Shepherd, S Rizzo, I Ledaki, M Davies, D Brewer, G Attard, J de Bono, ...
The Prostate 68 (9), 1007-1024, 2008
742008
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