| Low metformin causes a more oxidized mitochondrial NADH/NAD redox state in hepatocytes and inhibits gluconeogenesis by a redox-independent mechanism A Alshawi, L Agius Journal of Biological Chemistry 294 (8), 2839-5691, 2019 | 79 | 2019 |
| Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation T Moonira, SS Chachra, BE Ford, S Marin, A Alshawi, NS Adam-Primus, ... Journal of Biological Chemistry 295 (10), 3330-3346, 2020 | 30 | 2020 |
| Opposite effects of a glucokinase activator and metformin on glucose‐regulated gene expression in hepatocytes ZH Al‐Oanzi, S Fountana, T Moonira, SJ Tudhope, JL Petrie, A Alshawi, ... Diabetes, Obesity and Metabolism 19 (8), 1078-1087, 2017 | 26 | 2017 |
| Chronic glucokinase activator treatment activates liver Carbohydrate response element binding protein and improves hepatocyte ATP homeostasis during substrate challenge BE Ford, SS Chachra, A Alshawi, A Brennan, S Harnor, C Cano, DJ Baker, ... Diabetes, Obesity and Metabolism 22 (11), 1985-1994, 2020 | 14 | 2020 |
| Compromised chronic efficacy of a Glucokinase Activator AZD1656 in mouse models for common human GCKR variants BE Ford, SS Chachra, A Alshawi, F Oakley, RJ Fairclough, DM Smith, ... Biochemical Pharmacology 229, 116499, 2024 | | 2024 |
| The molecular mechanisms by which metformin inhibits gluconeogenesis AFO Alshawi Newcastle University, 2019 | | 2019 |
Loranne AgiusNewcastle University在 ncl.ac.uk 的电子邮件经过验证
