Prodrug strategies for targeted therapy triggered by reactive oxygen species JP Cadahía, V Previtali, NS Troelsen, MH Clausen MedChemComm 10 (9), 1531-1549, 2019 | 81 | 2019 |
Structure-activity relationships of new Organotin (IV) anticancer agents and their cytotoxicity profile on HL-60, MCF-7 and HeLa human cancer cell lines H Ullah, V Previtali, HB Mihigo, B Twamley, MK Rauf, F Javed, A Waseem, ... European Journal of Medicinal Chemistry 181, 111544, 2019 | 71 | 2019 |
Synthesis and evaluation of hydrogen peroxide sensitive prodrugs of methotrexate and aminopterin for the treatment of rheumatoid arthritis J Peiró Cadahía, J Bondebjerg, CA Hansen, V Previtali, AE Hansen, ... Journal of Medicinal Chemistry 61 (8), 3503-3515, 2018 | 59 | 2018 |
Methotrexate prodrugs sensitive to reactive oxygen species for the improved treatment of rheumatoid arthritis NS Andersen, JP Cadahía, V Previtali, J Bondebjerg, CA Hansen, ... European Journal of Medicinal Chemistry 156, 738-746, 2018 | 29 | 2018 |
A tomato tocopherol-binding protein sheds light on intracellular α-tocopherol metabolism in plants L Bermúdez, T Del Pozo, B Silvestre Lira, F de Godoy, I Boos, C Romano, ... Plant and Cell Physiology 59 (11), 2188-2203, 2018 | 23 | 2018 |
Theoretical Investigation of Cyano‐Chalcogen Dimers and Their Importance in Molecular Recognition V Previtali, G Sánchez‐Sanz, C Trujillo ChemPhysChem 20 (23), 3186-3194, 2019 | 14 | 2019 |
A theoretical model of the interaction between phosphates in the ATP molecule and guanidinium systems C Trujillo, V Previtali, I Rozas Theoretical Chemistry Accounts 135, 1-12, 2016 | 12 | 2016 |
Auxiliary in vitro and in vivo biological evaluation of hydrogen peroxide sensitive prodrugs of methotrexate and aminopterin for the treatment of rheumatoid arthritis V Previtali, K Petrovic, JP Cadahía, NS Troelsen, MH Clausen Bioorganic & medicinal chemistry 28 (2), 115247, 2020 | 11 | 2020 |
Effect of isouronium/guanidinium substitution on the efficacy of a series of novel anti-cancer agents V Previtali, C Trujillo, R Amet, DM Zisterer, I Rozas MedChemComm 9 (4), 735-743, 2018 | 6 | 2018 |
Sulochrins and alkaloids from a fennel endophyte Aspergillus sp. FVL2 M Shaaban, AS Abdel-Razek, V Previtali, MH Clausen, CH Gotfredsen, ... Natural Product Research 37 (8), 1310-1320, 2023 | 5 | 2023 |
Novel Insights into RAD52’s Structure, Function, and Druggability for Synthetic Lethality and Innovative Anticancer Therapies B Balboni, F Rinaldi, V Previtali, A Ciamarone, S Girotto, A Cavalli Cancers 15 (6), 1817, 2023 | 4 | 2023 |
Exploring the anti-cancer mechanism of novel 3, 4′-substituted diaryl guanidinium derivatives V Previtali, HB Mihigo, R Amet, AM McElligott, DM Zisterer, I Rozas Pharmaceuticals 13 (12), 485, 2020 | 4 | 2020 |
Development of the first model of a phosphorylated, ATP/Mg 2+-containing B-Raf monomer by molecular dynamics simulations: a tool for structure-based design V Previtali, C Trujillo, JC Boisson, H Khartabil, E Hénon, I Rozas Physical Chemistry Chemical Physics 19 (46), 31177-31185, 2017 | 3 | 2017 |
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic … SH Myers, L Poppi, F Rinaldi, M Veronesi, A Ciamarone, V Previtali, ... European Journal of Medicinal Chemistry 265, 116114, 2024 | 2 | 2024 |
Isolation and characterization of monomeric human RAD51: a novel tool for investigating homologous recombination in cancer F Rinaldi, F Schipani, B Balboni, F Catalano, R Marotta, SH Myers, ... Angewandte Chemie 135 (51), e202312517, 2023 | 2 | 2023 |
A Concise Total Synthesis of the Fungal Isoquinoline Alkaloid TMC-120B AK Haidar, ND Kjeldsen, NS Troelsen, V Previtali, KP Lundquist, ... Molecules 27 (2), 521, 2022 | 2 | 2022 |
Preomic profile of BxPC-3 cells after treatment with BRC4 V Previtali, SH Myers, L Poppi, K Wynne, I Casamassima, S Girotto, ... Journal of Proteomics 288, 104983, 2023 | 1 | 2023 |
Synthesis and evaluation of hydrogen peroxide sensitive tofacitinib prodrugs V Previtali, UB Keiding, AH Olsen, JP Cadahía, AS Clausen, A Kjaer, ... European Journal of Medicinal Chemistry Reports 4, 100019, 2022 | 1 | 2022 |
A novel aryl-guanidinium derivative, VP79s, targets the signal transducer and activator of transcription 3 signaling pathway, downregulates myeloid cell leukaemia-1 and … R Amet, V Previtali, HB Mihigo, E Sheridan, S Brophy, NK Hante, ... Life Sciences 290, 120236, 2022 | 1 | 2022 |
New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives V Previtali, G Bagnolini, A Ciamarone, G Ferrandi, F Rinaldi, SH Myers, ... Journal of Medicinal Chemistry, 2024 | | 2024 |